Conserved Protein Domain Family
Asp_protease

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pfam09668: Asp_protease 
Aspartyl protease
This family of eukaryotic aspartyl proteases have a fold similar to retroviral proteases which implies they function proteolytically during regulated protein turnover.
Statistics
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PSSM-Id: 312981
Aligned: 10 rows
Threshold Bit Score: 200.656
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q17569       221 KELIDEQYLHSMTHHPEDMIAVTMLYINLTINGVPVKAFIDSGAQKSIMSMACAERCGLNGLIDRRFQSMARGVgGTEKI 300 Caenorhabditis ...
NP_001040314 200 QKNIEANMEAAMEYNPETFGTVVMLYINCHVNGFPVKAFIDSGAQTTIMSAACAERCNIMRLVDTRWAGIAKGV-GVQRI 278
P0CS14       172 MEAVLENMQHAMEYSPESFGNVTMLYINVEVNGHPVKAFVDSGAQTTIISPECAEQCGIMRLLDTRFAGMAEGV-GTARI 250 Cryptococcus ne...
Q0U3Y6       180 QERVVENLEKAYNENPEVFVRVHMLYINTEVNGVPVKAFVDSGAQATIMSPDCAERCGIMRLMDTRYAGMARGV-GTARI 258 Parastagonospor...
Q5AY89       172 QNAVTENLHNAMEHHPESFGRVTMLYIPVEVNGHKLNAFVDSGAQVTIMSPDCATACNIMRLVDSRYGGIAKGV-GTANI 250 Aspergillus nid...
Q10256        87 QNAVTENMQSAIENHPEVFGQVYMLFVNVEINGHKVKAFVDSGAQATILSADCAEKCGLTRLLDTRFQGVAKGV-GMAKI 165 Schizosaccharom...
Q4E0H2       208 WENVNENLESAYEFMPELFVRVPMLFVNCEVNKVMVKAFIDSGAQRSIMNLRTAEKCGLMRLLDTRAKGIMRGV-GVRRT 286 Trypanosoma cruzi
CBZ11866      18 QQQIDENLANALEYTPEAFAKVTMLYVPCTINQVLVKAFVDSGAQNSIMNKRTAERCGLMRLVDVRMRGVAVGV-GRQEI 96 
Q7RA33       228 KNQINSNLALAQEHFPEAFGLVYMLYIPVEINKNVIHAFVDSGAQTSIISKRCAEKCNILRLMDTRFTGIAKGV-GTKSI 306 Plasmodium yoel...
Q54JB0       180 QQNIEKNMQHAMEHTPEVFASVYMLYIECSINGHPLKAFVDTGAQQSIMSEKCAERCEISRIIDTRFHGIAKGV-GTSKI 258 Dictyostelium d...
Q17569       301 EGKIHLCDVKVEDAHFSCPFEVMARREMDLLIGLNVLRKHGCCIN 345 Caenorhabditis elegans
NP_001040314 279 IGRIHMVQMRIEQDFLTTSFSVLEEQPMDMLLGLDMLKRHQCNID 323
P0CS14       251 LGRIHSAQIKLGSLYLPCAFSVLEGRSVDLLFGLDMLKRHQCCID 295 Cryptococcus neoformans var. neoformans JEC21
Q0U3Y6       259 LGRVHHAEIKIGGAVMPCAFTVMEGKDVDLLFGLDMLKRYKAKID 303 Parastagonospora nodorum SN15
Q5AY89       251 LGRVHSAQIKIGDMFLPCSFTVMEGKHIDLLLGLDMLRRHQACID 295 Aspergillus nidulans FGSC A4
Q10256       166 LGCVHSAPLKIGDLYLPCRFTVIEGRDVDMLLGLDMLRRYQACID 210 Schizosaccharomyces pombe 972h-
Q4E0H2       287 LGVVHMAMVNLGGLHIPLSLSIIDDDKMEFIIGLDQMKLHRMIID 331 Trypanosoma cruzi
CBZ11866      97 CGRIHMTPVNLAGMYIPFAFYVIEDQAMDLIIGLDQLKRHQMMID 141
Q7RA33       307 LGKIHMIDIKIGNYFYAVALTIIDDYDIDFIFGLDLLKRHQCSID 351 Plasmodium yoelii yoelii
Q54JB0       259 IGRVHSTDLKLGNSLFSVSLSILQNQDVDFILGLDMLKRHQVILD 303 Dictyostelium discoideum
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