Conserved Protein Domain Family
BUD22

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pfam09073: BUD22 
BUD22
BUD22 has been shown in yeast to be a nuclear protein involved in bud-site selection. It plays a role in positioning the proximal bud pole signal. More recently it has been shown to be involved in ribosome biogenesis.
Statistics
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PSSM-Id: 401132
View PSSM: pfam09073
Aligned: 65 rows
Threshold Bit Score: 59.8481
Threshold Setting Gi: 268562776
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ERS97129              52 YtDVLRMLKKARGFERQRLVRRIaeeKTQSKtgkkskgkkakksaadnvdgdgdgdtDQRSERLQRLE------------ 119  Sporot...
EKD01031             688 RtKLHQLFKQAKREESQRLIKKI---KFLSK--------------------------KGSSSEADELD------------ 726  Tricho...
Q5KCW5                93 K-SLHPVFKQAKTFETRRLIKKI---KFLRN--------------------------KDVKDETADLE------------ 130  Crypto...
XP_001876195          22 K-EVHKASKKAKVFETQKLVKRL---KDLRRk-------------------------GDDPKAIEEHE------------ 60   Laccar...
WGS:AACS:CC1G_12320   34 Q-EVYQACKKAKTFETQKLVKKL---KGLRKd-------------------------SSDTNAVQEHE------------ 72   Coprin...
EGN98387               7 R-EVRKAAKKAKTFETQKLLKKL---KDLRRk-------------------------AEKPNEITDAE------------ 45   Serpul...
XP_007399343          24 K-ELKKAAKKAKDFEIRKLVKRL---KGLRVk-------------------------KPAPPELRDLE------------ 62   Phaner...
NP_492224            116 V-ALRATCLTAKNQLMSRIVRQK---KQLE---------------------------SKKSQKVDGKSkeerdrkiarlv 164  Caenor...
XP_006959516          44 NvDLRRATKDAKTSERQRLQKKI---TQAEKksa--------------------kgeEIDRVQLEETQ------------ 88   Wallem...
EOQ99199             122 HvDLRRAVKDARVSEHKRLQKKL---TQLEKmss--------------------kgeKVDSQQQEEAQ------------ 166  Wallem...
ERS97129             120 REVEVLKTLDYEVTAR-VHLANAMLRTRGLAEAPgplgahlqLASEVLS-----------QRTKAYRTDDIHNVTSALYN 187  Sporot...
EKD01031             727 TQLKLLGAVDLHILSA-NHLKLKLRKHYLLKKDG--------MPSDVESviggg--qtvkASGSNATPEVIAKVENRLCS 795  Tricho...
Q5KCW5               131 SQLKIIHDIQLQPLAK-SHLLVKLRKHPLFKQTP--------LPSEISSllsppsattasFAGTSATPALINKAENRLCS 201  Crypto...
XP_001876195          61 EQLTLLKSVDHDTIGN-TAFKTKILKDNSLRENDf-------VQAALSSevgenvt------tpakpgTPLAKVQSRLLS 126  Laccar...
WGS:AACS:CC1G_12320   73 AQLTALKELDIHSIAR-TAFKTKVLKDRTLRDSEl-------IMSGLEKeitnti-------ipspasTPLGKVQSRLLS 137  Coprin...
EGN98387              46 AQLDAIKHITLDVIAD-TALRTKMNKDHILSTNEd-------LQHALSMellpspi------asaaagSHLAKVQSRLLS 111  Serpul...
XP_007399343          63 EQLVLLKEIDHKTIAS-MALKTKLKKDKQLSENEn-------LVAAISQelscli-------vpaqpgSNLAKVQGRLLS 127  Phaner...
NP_492224            165 EEILGLKTFDKDSVAKfAALNTKSLAELKINGKT----------------------------------EVAERLMYKLVC 210  Caenor...
XP_006959516          89 NQLNETKDYDGLIAAQ-HTFFSKLSKH-----SSgayktreeVILALKNlnfdfpni------aqasnapeGKLAARFMS 156  Wallem...
EOQ99199             167 NQLIETKEYDGLPAAQ-HTFFSKLSKH-----NQgafksreeVIHALNKlsfnwpai------slpsnapqGKVAARFMS 234  Wallem...
ERS97129             188 RPFVRDAVAKAVA-GM---CQLLGLPP----------PEKSVSRVRKQRKEEDEEED------------EEEEKDSVDdd 241  Sporot...
EKD01031             796 AKNVADGVKGIVSwCLaepGSSLNLDKmkekknkknaKPESDEDSDDASEGDDEREDdva-------nvVGELDSDDEvv 868  Tricho...
Q5KCW5               202 AKIVAERMKNVVSwTVcegGAKLVIEKkpatisagkgGSKKAAESTDEEDDEQEEGEeanv-----gdiSRSMVNGSD-- 274  Crypto...
XP_001876195         127 SKLLAAQIVVSIE-NL---RMLLDPTLrgpka-egteEDTAVPAPKRKKAPTLSGEQsvah-----aamEDCESDGDE-- 194  Laccar...
WGS:AACS:CC1G_12320  138 SKHLSSQISISID-GL---KVILDPEYapqqkkqrttSAEPPNAASIASSKRTRTQRhskegslqaadvGSESEDSED-- 211  Coprin...
EGN98387             112 SKVLASEISIVIG-GI---KATINPAFaaaqd-aaseGESDADVPAVPRKTKRVSADkst-------------------- 166  Serpul...
XP_007399343         128 HKVIAAEVHTIVE-DV---RTTVFPELkltavteasdGELHEDVPLRPTKKVKMVSAgp---------eKTDEGDSDD-- 192  Phaner...
NP_492224            211 QSIIVEKIQSIREkYTewnKTAAFFMQrlgqq-yankPEKKSKKSTEKKELNIENLEd----------lNNEDEDSEN-- 277  Caenor...
XP_006959516         157 IEQVSKVAKAGVD-SV---SSILGDSA----------AEKQKQSEQLEDSKESAEDDevd-------dkLESNTTSDKpa 215  Wallem...
EOQ99199             235 IEQISSVAKSAVD-SV---VSILGDGA-------------------------KKENEvnvqa--eqvpaDDKQIKNDKtl 283  Wallem...
ERS97129             242 trrhtqantpkdktIAWRSESSEDEEADDDNDEDTEDnmeyneaddkaie------------------------------ 291  Sporot...
EKD01031             869 ve--------ekaaDAAGWESGDLGGEGSDEDDEEGEdgwesgsvggee------------------------------- 909  Tricho...
Q5KCW5               275 ---------------SEEDSDDERVLQDRAAD----Aagwes-------------------------------------- 297  Crypto...
XP_001876195         195 ----------------WKGVDDENQDMADAAIGDGVDdgwesgtvgegdd------------------------------ 228  Laccar...
WGS:AACS:CC1G_12320  212 ------------------DDLRDEEGADDESEDGDGAdgwesgsisgdedyvgrl-----------------------ap 250  Coprin...
EGN98387             167 -----------hghSMSVPEKNEEDGGNAEEDENILDdgwesgtisggdqas---------------------------- 207  Serpul...
XP_007399343         193 -------------------ESSLNNRVTISDEEEVADdgwdsgtvhgesdseeeed---------------------nka 232  Phaner...
NP_492224            278 -------------------EKEEEIEENEEDydqsd-------------------------------------------- 294  Caenor...
XP_006959516         216 p-----------reQKATPTIDSSALIAKLTGALGGVvrddededndaqsdagsdisaplsgytsgeasneedalkdwpe 284  Wallem...
EOQ99199             284 qp--------ptqiKKERPATDNSALIAKLTNSLGGTvrddddeeeedqeadsdaplsgytsgeasddalqnwpdpdads 355  Wallem...
ERS97129             292 ---relakfesrlgsDEDDDEDesdendseddglgsgsdddsdgdldddavvaklrakyaaavakglwqdddrdrddfsg 368  Sporot...
EKD01031             910 ----gtgedawiasaSDSDAPDyaalanl--------------------------------------------------- 934  Tricho...
Q5KCW5               298 ----------gsvsgFDSEGGE---------------------------------------------------------- 309  Crypto...
XP_001876195         229 ---vagsdgwesssiGNDDDVSedgdrlel-------------------------------------------------- 255  Laccar...
WGS:AACS:CC1G_12320  251 sspvgsdeensgseqDDDDDSD---------------------------------------------------------- 272  Coprin...
EGN98387             208 -edewesgsvddvhhGTKEDGD---------------------------------------------------------- 228  Serpul...
XP_007399343         233 edngvasevktkdgeSDDEDTvsrs------------------------------------------------------- 257  Phaner...
NP_492224            295 ----------iemldSDEEEAGee-------------------------------------------------------- 308  Caenor...
XP_006959516         285 peeevdesneeeeeeSDDEDEG---------------------------------------------------------- 306  Wallem...
EOQ99199             356 dgdddnddinnddinNDDDDAD---------------------------------------------------------- 377  Wallem...
ERS97129             369 edsdgadfeeeqdDEQGEGGEEEEEFGGFSDDGEVDDESESESDED-----------------LRPRKRKATSATTFDgT 431  Sporot...
EKD01031             935 -------kggageDWSSGSEGDSDAGSASDSSSGSSVAVERPPAKKvkaevskkaekpvkaekKPEKKAAKAEKPKPDgT 1007 Tricho...
Q5KCW5               310 ----------------VDIASESESESDNSDAIAVPSAKRAKTAVPplppk--------skplKSEKADKPPKSAKDLtS 365  Crypto...
XP_001876195         256 --------------------------------------------------------hakpavkKSATAALKAKASASGlQ 279  Laccar...
WGS:AACS:CC1G_12320  273 ----------------------------------------PESDEDtkpmkkanaggstssktPKVASGASSKPAKIN-E 311  Coprin...
EGN98387             229 ------------------------------------YSSGSEGNLAapss----------pplPNESKPHQGKAKTVGsQ 262  Serpul...
XP_007399343         258 ------------------------------------------------------------kqpPRKTPPPRASTSKKG-E 276  Phaner...
NP_492224            309 --------------------------------------------------------------aAKNRRNLLLGLIGVQ-E 325  Caenor...
XP_006959516         307 -------------------------------------------------------------------------------G 307  Wallem...
EOQ99199             378 -----------------------------------------------------------------------------N-G 379  Wallem...
ERS97129             432 SHFLPSL-MG-GYVSdGGDDa------dGVADDE--------EAAArmlggpRKNRRGQRARQAIWEK-------KYKQL 488  Sporot...
EKD01031            1008 SMFLPSL-AA-GFTA-GDSD--------SDPDMDydpdgvigNKAAp-----RKNRRGQRARQAIWEK-------KYGKN 1064 Tricho...
Q5KCW5               366 SIFLPSL-SV-GFTR-GDDDd-------SDPDLDddpngvagKQPVv-----RKNRRGQRARQAIWEK-------KYGKN 423  Crypto...
XP_001876195         280 STFLPSL-SV-GFVR-GGSEesdwseegRVADIDv-----------------KKNRRGQRARRAIWEK-------KYGRN 332  Laccar...
WGS:AACS:CC1G_12320  312 STFLPSL-QV-AYIS-GSDDsd-----aEAEVAEp-----------------RKNRRGQRARRAIWEK-------KYGRN 359  Coprin...
EGN98387             263 STFLPSL-AV-GFAR-GDSDsdw--sesEAKDADg----------------iKKNRRGQRARRAIWEK-------KFGKN 314  Serpul...
XP_007399343         277 STFFPSL-AV-GFTR-GDSDasdl-sdaEVARAEgg---------------aRKNRRGQRARRAIWEK-------KYGKN 330  Phaner...
NP_492224            326 DKNRPSL---------------------APKKRKlveeedeeVETV----------KNQKKMKQIFEKelkskevKNPKK 374  Caenor...
XP_006959516         308 NTILDSLnAGvGYIS-GSDD--------DISDAEe------kVAP-------RKNRMGQRARRAILEK-------KYGRG 358  Wallem...
EOQ99199             380 NALLNSLnTGvGYIS-GGSD--------DISDAEe------kVAP-------RKNRMGQRARRMIHEK-------KFGRG 430  Wallem...
ERS97129             489 AKHvLEQEKKGTDAGGKDGGKDKKank---------------------------------------ngkQKDggGGWD-- 527  Sporot...
EKD01031            1065 AKHiVKQREEEKKKAAKKEGRVGGsnf---------------------------------------vppSRD--SGYK-- 1101 Tricho...
Q5KCW5               424 AKH-VVKAHEEEKLQAQKTREKAEak-----------------------------------------grTRD--SGWG-- 457  Crypto...
XP_001876195         333 ANH-KKKESEESTKFGSVRGEPPRprqlhnhppssga--------------------srkikptsqqrqPPD--MGWG-- 387  Laccar...
WGS:AACS:CC1G_12320  360 ANH-KKAEAKAApttavkqn-----------------------------------------pegrsfahPKQprGG---- 393  Coprin...
EGN98387             315 ANH-VKRYQDDPSRRERPTERRRGsqplgqrnsdrp---------------------rkrdtsnqqhqqPPD--AGWNrr 370  Serpul...
XP_007399343         331 ANHfKKRETFGAVKGYPNKTSDRDvngsrdnprgns----------------------qankrphaqaqSRN--VTYSqr 386  Phaner...
NP_492224            375 SNKsTKKPTKSAPIVKKVEEKKVEenevsddesdqktlvmkvdlskggkiakaqkfsttapksakivapVSE-------- 446  Caenor...
XP_006959516         359 ANH-IQKK--FEEQKQLERAKKFGk-------------------------------------------nKLD--SGWKgr 390  Wallem...
EOQ99199             431 ANH-VQKK--FEEDKQLERAKRMGr-------------------------------------------nKLD--SGWKgr 462  Wallem...
ERS97129             528 ----AKRGAVDASDK--------PRWLrrkmgllgrvgp-----vggggkgagsnATPPAGAKKEIPNANAQVSGTLHPS 590  Sporot...
EKD01031            1102 ----TYRPAPESAPVlakpggtfGSSApar-----------------------tpGAATAGGASGPGAGGDEKKGKNHPS 1154 Tricho...
Q5KCW5               458 ----AKSGKAVGPAVaagpaqtaA-------------------------------VSHTQKVYSEPKQSQTEQKKSLHPS 502  Crypto...
XP_001876195         388 -------------------------------------------------------QRRIGPNKIPPSKSETKADQSLHPS 412  Laccar...
WGS:AACS:CC1G_12320  394 ----VRRGPLVSGPNsaaiqgkqRAF-----------------------------GQKPPTGAAAPSTNSNPSNKPLHPS 440  Coprin...
EGN98387             371 epsnSHTKSIVGT------------------------------------------RSTIVSSAGSSQRNDRHDERPLHPS 408  Serpul...
XP_007399343         387 ------------------------------------------------------aSSSHVSSVQTGPTTRKERDKPLHPS 412  Phaner...
NP_492224            447 ----------DENDDdesssfflPKSGvvaprkiipkkpsenvekvdkrfqkgtqKKSEAVVEKKKGSSKSAVSGEMHPS 516  Caenor...
XP_006959516         391 qqqqsggykeaerkdfk-------------------rdfkkfdknakqdgksgsgRPPPRNNKPPQKPTKAEDEGPLHPS 451  Wallem...
EOQ99199             463 qqrqsedqkpnkdlnggykkdf---------kkdnktdsnhsskhdrgyknhskpHSKPSVPIKPGTDAAADDQGQLHPS 533  Wallem...
ERS97129             591 WEAARKAKD--KAQTAAFEGKKIVFD 614  Sporothrix schenckii ATCC 58251
EKD01031            1155 WEAARRRKEaeQKLKNAPKATKIVFD 1180 Trichosporon asahii var. asahii CBS 8904
Q5KCW5               503 WEAAKLRKQkmGVVQTEIKAQKIVFD 528  Cryptococcus neoformans
XP_001876195         413 WEAKRKLKLkeSAGIIPSQGTKIKFs 438  Laccaria bicolor S238N-H82
WGS:AACS:CC1G_12320  441 WEAKKKLKEk-QSGIVPSQGKKIKF- 464  Coprinopsis cinerea okayama7#130
EGN98387             409 WEAKKKQK---TAGIVPSQGKKIVFs 431  Serpula lacrymans var. lacrymans S7.3
XP_007399343         413 WEAKRKLKEkqNPALIAPRGKKIVFe 438  Phanerochaete carnosa HHB-10118-sp
NP_492224            517 WIASQLKKK--ELASAKPCGKKITFg 540  Caenorhabditis elegans
XP_006959516         452 WAAKKAQAKaiENAPAP---TKITFD 474  Wallemia mellicola CBS 633.66
EOQ99199             534 WAAKKAQAEaiANAPAP---TKITFD 556  Wallemia ichthyophaga EXF-994
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