Conserved Protein Domain Family
BUD22

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pfam09073: BUD22 
BUD22
BUD22 has been shown in yeast to be a nuclear protein involved in bud-site selection. It plays a role in positioning the proximal bud pole signal. More recently it has been shown to be involved in ribosome biogenesis.
Statistics
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Aligned: 69 rows
Threshold Bit Score: 55.9866
Threshold Setting Gi: 187029941
Created: 3-May-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ERS97129             52 YtDVLRMLKKARGFERQRLVRRIaeeKTQSKtgkkskgkkakksaadnvdgdgdgdtDQRSERLQRLE------------ 119 Sporothr...
EED82280             25 K-EMRKVVKKEKTFETQKIVKKL---KTLRAkd-----------------------pERNAKMILDFE------------ 65  Postia p...
EMD39958             37 R-EVRKAAKKAKIFEVQKLVKRL---KSLRAk-------------------------DPAADAIAGLE------------ 75  Gelatopo...
EDR13697             22 K-EVHKASKKAKVFETQKLVKRL---KDLRRk-------------------------GDDPKAIEEHE------------ 60  Laccaria...
WGS:AACS:CC1G_12320  34 Q-EVYQACKKAKTFETQKLVKKL---KGLRKd-------------------------SSDTNAVQEHE------------ 72  Coprinop...
EGN98387              7 R-EVRKAAKKAKTFETQKLLKKL---KDLRRk-------------------------AEKPNEITDAE------------ 45  Serpula ...
EKM51531             24 K-ELKKAAKKAKDFEIRKLVKRL---KGLRVk-------------------------KPAPPELRDLE------------ 62  Phaneroc...
XP_016273365         50 K-VLHKAVKKSKTFELQKLTRKL---KSTREpk----------------------egAVDSALLADLE------------ 91  Rhodotor...
KDE07903             49 K-LLHKVVKKSKTFELQKLTRKL---KRAGEt------------------------eGVATTVVADLE------------ 88  Microbot...
NP_492224           116 V-ALRATCLTAKNQLMSRIVRQK---KQLE---------------------------SKKSQKVDGKSkeerdrkiarlv 164 Caenorha...
ERS97129            120 REVEVLK-------TL-----------DYEVTAR-VHLANAMLRTRGLAEAPgplgahlqLASEVLS-------QRTKAY 173 Sporothr...
EED82280             66 SQLEVIKvhtpirhSIslhvlttdqhlDHEPIAN-LAFKTKLNKDRLLLQNEh-------MQTAISTeltpnll--tsad 135 Postia p...
EMD39958             76 AELEALK-------HV-----------DHEPVAK-SALKSKLKKDRILASNTh-------AQAAIAAelttdll--tpsa 127 Gelatopo...
EDR13697             61 EQLTLLK-------SV-----------DHDTIGN-TAFKTKILKDNSLRENDf-------VQAALSSevgenvt--tpak 112 Laccaria...
WGS:AACS:CC1G_12320  73 AQLTALK-------EL-----------DIHSIAR-TAFKTKVLKDRTLRDSEl-------IMSGLEKeitnti---ipsp 123 Coprinop...
EGN98387             46 AQLDAIK-------HI-----------TLDVIAD-TALRTKMNKDHILSTNEd-------LQHALSMellpspi--asaa 97  Serpula ...
EKM51531             63 EQLVLLK-------EI-----------DHKTIAS-MALKTKLKKDKQLSENEn-------LVAAISQelscli---vpaq 113 Phaneroc...
XP_016273365         92 AQLAALK-------KV-----------DLNSIPV-HILASRLPKIHSLRSAPf-------YPSVTAAipp-spsKWVDLD 144 Rhodotor...
KDE07903             89 AQLDALK-------GL-----------PIDPLAT-HILHTRLGKISSPTLSKh-------LPTLTASlpaqvppTTTETD 142 Microbot...
NP_492224           165 EEILGLK-------TF-----------DKDSVAKfAALNTKSLAELKINGKT---------------------------- 198 Caenorha...
ERS97129            174 RTDDIHNVTSALYNRPFVRDAVAKAVA-GM---CQLLGLPP----------PEKSVSRVRKQRKEEDEEED--------- 230 Sporothr...
EED82280            136 pgTAARKVQDRLLSSKTLAVEVLSVLT-AL---KELVDPSLrkgpe-qapgAEGSDNESPSKVKKTKAPSR--------- 201 Postia p...
EMD39958            128 agTPAARVESRLLSSKTLAAEVHAVVD-SL---KEVIVPTKkakke-aqteEKEGDGEDDDDNADVERPAKa-------- 194 Gelatopo...
EDR13697            113 pgTPLAKVQSRLLSSKLLAAQIVVSIE-NL---RMLLDPTLrgpka-egteEDTAVPAPKRKKAPTLSGEQsvah----- 182 Laccaria...
WGS:AACS:CC1G_12320 124 asTPLGKVQSRLLSSKHLSSQISISID-GL---KVILDPEYapqqkkqrttSAEPPNAASIASSKRTRTQRhskegs--- 196 Coprinop...
EGN98387             98 agSHLAKVQSRLLSSKVLASEISIVIG-GI---KATINPAFaaaqd-aaseGESDADVPAVPRKTKRVSADkst------ 166 Serpula ...
EKM51531            114 pgSNLAKVQGRLLSHKVIAAEVHTIVE-DV---RTTVFPELkltavteasdGELHEDVPLRPTKKVKMVSAgp------- 182 Phaneroc...
XP_016273365        145 AQSAEGKARNRVMANKAIAESWDEVVR-AV---RKRLGEEV----------EAPGKDVKGKAKAKEQDEQGgffeeeekr 210 Rhodotor...
KDE07903            143 ATSTPGKARNRVLANKTVHEGWEEIVR-AI---KKRLGEEV----------APRPVAIKAVPAKSPSKDKKslvqdgvgv 208 Microbot...
NP_492224           199 --EVAERLMYKLVCQSIIVEKIQSIREkYTewnKTAAFFMQrlgqq-yankPEKKSKKSTEKKELNIENLEd-------- 267 Caenorha...
ERS97129            231 -----------------------------------EEEEKDSVDddtrrhtqantpkdktIAWRSESSEDEEADDDNDED 275 Sporothr...
EED82280            202 -------------------------------------------------------------PVGGSGDEHESGDESIALE 220 Postia p...
EMD39958            195 ------------------------------------------------------------KKRESAAKLHVEAADDSDAE 214 Gelatopo...
EDR13697            183 --------------------------------aamEDCESDGDE------------------WKGVDDENQDMADAAIGD 212 Laccaria...
WGS:AACS:CC1G_12320 197 -----------------------------lqaadvGSESEDSED--------------------DDLRDEEGADDESEDG 227 Coprinop...
EGN98387            167 ---------------------------------------------------------hghSMSVPEKNEEDGGNAEEDEN 189 Serpula ...
EKM51531            183 ----------------------------------eKTDEGDSDD---------------------ESSLNNRVTISDEEE 207 Phaneroc...
XP_016273365        211 eapkskgitmdpgrlaaieaasmensadeaeeaeaAEQAEGAGEdvs-----------evSPDKLAALEAAFLQGRGDDD 279 Rhodotor...
KDE07903            209 assstngtkldaspgpavvgerrlskraerklkgeLKAKQPREMtidpq-------rlkaMQRASERERGDDEEDGGDED 281 Microbot...
NP_492224           268 ----------------------------------lNNEDEDSEN---------------------EKEEEIEENEEDydq 292 Caenorha...
ERS97129            276 TEDnmeyneaddkaie-----------------------------------------relakfesrlgsDEDDDEDesde 314 Sporothr...
EED82280            221 VDAagwesgtvrgdddedgwesgsvddan--------------prgqsiaggadsdgseaddsgnedenSDDEEEEe--- 283 Postia p...
EMD39958            215 VDDagwesgsihgenededqpadd------------------------gwesgsvdggrpggtallgdeSSDEDEDe--- 267 Gelatopo...
EDR13697            213 GVDdgwesgtvgegdd-----------------------------------------vagsdgwesssiGNDDDVSedgd 251 Laccaria...
WGS:AACS:CC1G_12320 228 DGAdgwesgsisgdedyvgrl-------------------------------apsspvgsdeensgseqDDDDDSD---- 272 Coprinop...
EGN98387            190 ILDdgwesgtisggdqas-------------------------------------edewesgsvddvhhGTKEDGD---- 228 Serpula ...
EKM51531            208 VADdgwdsgtvhgesdseeeed-----------------------------nkaedngvasevktkdgeSDDEDTvsrs- 257 Phaneroc...
XP_016273365        280 DGEmseddgpvlgisedegepaqqeaeeevedeeegsddedevdedeairrelaaledgegsegawsdsAEEEDAD---- 355 Rhodotor...
KDE07903            282 GGEfgidddevrreleal------------------------------------ggdggtdwsgsesgaEDEADDD---- 321 Microbot...
NP_492224           293 sd--------------------------------------------------------------iemldSDEEEAGee-- 308 Caenorha...
ERS97129            315 ndseddglgsgsdddsdgdldddavvaklrakyaaavakglwqdddrdrddfsgedsdgadfeeeqddeqgEGGEEEEEF 394 Sporothr...
EED82280            284 ----------------------------------------------------------------------eEDDDDDYDV 293 Postia p...
EMD39958                -------------------------------------------------------------------------------- Gelatopo...
EDR13697            252 rlel---------------------------------------------------------------------------- 255 Laccaria...
WGS:AACS:CC1G_12320     -------------------------------------------------------------------------------- Coprinop...
EGN98387                -------------------------------------------------------------------------------- Serpula ...
EKM51531                -------------------------------------------------------------------------------- Phaneroc...
XP_016273365        356 -------------------------------------------------------------------------DDGASVA 362 Rhodotor...
KDE07903            322 -------------------------------------------------------------------------DDGASIA 328 Microbot...
NP_492224               -------------------------------------------------------------------------------- Caenorha...
ERS97129            395 GGFSDDGEVDDESESESDED-----------------LRPRKRKATSATTFDgTSHFLPSLMGGYVSd--GGDDa----- 450 Sporothr...
EED82280            294 DGGDNAAVAIASATKRASQQaekg----------kkvALPAKDTKGKSKATA-ESTFLPSLSVGFTR---GDSDasdl-s 358 Postia p...
EMD39958            268 --------dPSASDSEVQPPprkv----------akpSTATHDAKGKSKATSaESTFLPSLSVGFTR---GDSDasdl-s 325 Gelatopo...
EDR13697            256 ------------------------------hakpavkKSATAALKAKASASGlQSTFLPSLSVGFVR---GGSEesdwse 302 Laccaria...
WGS:AACS:CC1G_12320 273 --------------PESDEDtkpmkkanaggstssktPKVASGASSKPAKIN-ESTFLPSLQVAYIS---GSDDsd---- 330 Coprinop...
EGN98387            229 ----------YSSGSEGNLAapss----------pplPNESKPHQGKAKTVGsQSTFLPSLAVGFAR---GDSDsdw--s 283 Serpula ...
EKM51531            258 ----------------------------------kqpPRKTPPPRASTSKKG-ESTFFPSLAVGFTR---GDSDasdl-s 298 Phaneroc...
XP_016273365        363 SDSSFPTKSAKRRQpsls----------------ptpPPRPAKKAKASKPLT-SSAFLPTLASGYIGydsDDEDakwl-k 424 Rhodotor...
KDE07903            329 SDSSFPVVAASKATTPKVKAkstpv--------dtklDKQPKKESTTTRPIT-SSAFLPSLAAGYVSysdSDDDdakwvk 399 Microbot...
NP_492224           309 ------------------------------------aAKNRRNLLLGLIGVQ-EDKNRPSL------------------- 332 Caenorha...
ERS97129            451 -dGVADDE--------EAAArmlggpRKNRRGQRARQAIWEK-------KYKQLAKHvLE---------------QEKKG 499 Sporothr...
EED82280            359 deEVKVADm-----------------RKNRRGQRARRAIWEK-------KYGGNANH-VK---------------KEREA 398 Postia p...
EMD39958            326 dsEAKAADn----------------gRKNRRGQRARRAIWEK-------KYGRNANH-VK---------------KEHET 366 Gelatopo...
EDR13697            303 egRVADIDv-----------------KKNRRGQRARRAIWEK-------KYGRNANH-KK---------------KESEE 342 Laccaria...
WGS:AACS:CC1G_12320 331 -aEAEVAEp-----------------RKNRRGQRARRAIWEK-------KYGRNANH-KK---------------AEAKA 369 Coprinop...
EGN98387            284 esEAKDADg----------------iKKNRRGQRARRAIWEK-------KFGKNANH-VK---------------RYQDD 324 Serpula ...
EKM51531            299 daEVARAEgg---------------aRKNRRGQRARRAIWEK-------KYGKNANHfKK---------------RETFG 341 Phaneroc...
XP_016273365        425 qaEKEDAKdr---------------aRKNRPGQRARRAMWEK-------EYGEKANHiVVanggkplsakemkalQEKEA 482 Rhodotor...
KDE07903            400 daERQDKRee---------------kRKNRRGQRARQAIWEK-------KYGSGANHvVK---------------ET--- 439 Microbot...
NP_492224           333 --APKKRKlveeedeeVETV----------KNQKKMKQIFEKelkskevKNPKKSNKsTK---------------KPTKS 385 Caenorha...
ERS97129            500 TDAGGKDGGKDKKank---------------------------------------ngkQKDggGGWD------AKRGAVD 534 Sporothr...
EED82280            399 MAQEPRNQRRGDPhgrnrthppggs---------------------rkggppsafrapPSD--KGWMkk----------- 444 Postia p...
EMD39958            367 TAQNPRQKG------------------------------------------------------AGWNqkggprNAGPPGR 392 Gelatopo...
EDR13697            343 STKFGSVRGEPPRprqlhnhppssga--------------------srkikptsqqrqPPD--MGWG------------- 387 Laccaria...
WGS:AACS:CC1G_12320 370 Apttavkqn-----------------------------------------pegrsfahPKQprGG--------VRRGPLV 400 Coprinop...
EGN98387            325 PSRRERPTERRRGsqplgqrnsdrp---------------------rkrdtsnqqhqqPPD--AGWNrrepsnSHTKSIV 381 Serpula ...
EKM51531            342 AVKGYPNKTSDRDvngsrdnprgns----------------------qankrphaqaqSRN--VTYSqr----------- 386 Phaneroc...
XP_016273365        483 ARRKDGRDGRPRQqqdrqqgfkrdanaqrpqggr----pprpdrpqqqqrdrpardaqPRAqdQGWQ------------- 545 Rhodotor...
KDE07903            440 ----------------------------------------------------------------------------GGAA 443 Microbot...
NP_492224           386 APIVKKVEEKKVEenevsddesdqktlvmkvdlskggkiakaqkfsttapksakivapVSE------------------D 447 Caenorha...
ERS97129            535 ASDK--------PRWLrrkmgllgrvgp-----------------------------------vggggkgagsnATPPAG 571 Sporothr...
EED82280            445 ------------------------------------------------------------------------geAPNVPS 452 Postia p...
EMD39958            393 RGPPpsqvrpnvPHQ-----------------------------------------------------------GHASEG 413 Gelatopo...
EDR13697            388 --------------------------------------------------------------------------QRRIGP 393 Laccaria...
WGS:AACS:CC1G_12320 401 SGPNsaaiqgkqRAF-----------------------------------------------------------GQKPPT 421 Coprinop...
EGN98387            382 GT------------------------------------------------------------------------RSTIVS 389 Serpula ...
EKM51531            387 -------------------------------------------------------------------------aSSSHVS 393 Phaneroc...
XP_016273365            -------------------------------------------------------------------------------- Rhodotor...
KDE07903            444 AAQKggkasskkAITKaalnhtvtpydptktpgaannpnaapvgqrkivrptvtyktstpivpieivnlsssgiRPADST 523 Microbot...
NP_492224           448 ENDDdesssfflPKSGvvaprkiipkkpse------------------------------nvekvdkrfqkgtqKKSEAV 497 Caenorha...
ERS97129            572 AKKEIPNANAQVSGTLHPSWEAARKAKD--KAQTA-AFEGKKIVFD 614 Sporothrix schenckii ATCC 58251
EED82280            453 HASLPPKAKSKDDKPLHPSWEAKKRLNEklKPVIL-PPQGKKIIFs 497 Postia placenta Mad-698-R
EMD39958            414 RPQPRPTKTEVQDKPLHPSWEAKKRLKEkqNPTIM-APQGKKITFs 458 Gelatoporia subvermispora B
EDR13697            394 NKIPPSKSETKADQSLHPSWEAKRKLKLkeSAGII-PSQGTKIKFs 438 Laccaria bicolor S238N-H82
WGS:AACS:CC1G_12320 422 GAAAPSTNSNPSNKPLHPSWEAKKKLKEk-QSGIV-PSQGKKIKF- 464 Coprinopsis cinerea okayama7#130
EGN98387            390 SAGSSQRNDRHDERPLHPSWEAKKKQK---TAGIV-PSQGKKIVFs 431 Serpula lacrymans var. lacrymans S7.3
EKM51531            394 SVQTGPTTRKERDKPLHPSWEAKRKLKEkqNPALI-APRGKKIVFe 438 Phanerochaete carnosa HHB-10118-sp
XP_016273365        546 ---TAPKKADAPAEKMHPSWEAKRKAAEalKLSAVsKPAGKKIVFD 588 Rhodotorula toruloides NP11
KDE07903            524 RSAPVVRGKPLVEEGMHPSWEAKRRAQEalLNSAN-APKGKKITFs 568 Microbotryum lychnidis-dioicae p1A1 Lamole
NP_492224           498 VEKKKGSSKSAVSGEMHPSWIASQLKKK--ELASA-KPCGKKITFg 540 Caenorhabditis elegans
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