RMA97819               1 MIIRKEHALALLNAKSQEEKGLA-CQIRV-KA--EEEp--YVELELQNLLEQg--sSPIEFTLTYWGRNLVYLMEEMIQK 72 
Q9X0A7                 1 MIVTKRHAIVLKKLYE--KGEEFsVKEWE-DF--DREt--LWHLELAGLVKPv---GVEMYDLTFSGNILGELLTDMIRE 70  Thermot...
BAT71239               1 MVVTGEGVRILKSIAEGKEITKEtEE--------------ARVLELAGILRYd---LPGKYSLTYTGESLVDLIRSIEEK 63 
GCE22002               1 MLLTTAHLIALRTLSDSEIAGHTaYVPEEsDDqnHI----YRELELQGLAVLv---pPRAYQITFTGHEALGIFDGMQKS 73 
RAQ94616               1 MLLTGAHVAALRELASSEEAGQAaYELAE-DDr-RALt--YRALELQGLAALe---LPRSYRLTYAGREALQLLEEMRRD 73 
PRJNA61347:EYM_06845   1 MLLKREYLEMLEEVGDKELDINEfVKGE--YEerERLiknLLALELQDLIRPkdarNPRIFVLTEHGKKVLDIWKRL--- 75 
jgi:Igni_0126          1 MLLKREYMQVLEKFKGKDEVDVAeVATGE-YEeaENVlfiLLALEVQGLIEPvskeRPRSFRLTEAGKKVLEAWEEA--- 76 
Q8TZ95                 1 MLLLKDHAEVLLTVEELGTREEArEIAEEaEAvtEIIpqrLLELELQGLMKRv---gPNEWELTDAGKTAAKAVAEA-VD 76  Methano...
Q5JFF3                 1 MYLKKRHIEILREMKNTESQAEIeAKLPE-DFqiR-----AIELYILGFAEL----EGGKIKLTDAGRKLLEITDKLSLE 70  Thermoc...
BAF69133               1 MVIKKEAAKILLALHRSDDKTINvEKLNK-EA--------VEELNLSGLVRFp---IPAKIELTYSGSIVAQILADI--E 66 

RMA97819              73 GLIKHP--------------SEWDERFRWIGSEVIAMIEASIRSGDLTGEEIFDALKERGFAEEVHeekk-gwfkKINDY 137
Q9X0A7                71 GVLKNP--------------EEWDDSFRWIGSEVISMIRYSKLAQSRVRGEVAKALEERGFAKEGN----------LTPY 126 Thermot...
BAT71239              64 GVDT----------------SKWEDNFRFVGSEVIAMIDSVIRAKGRVFEDFVKPLEERGFVKDGE----------LTPE 117
GCE22002              74 SSIPPI--------------DQLKKDWRLLGSDIQAALHAAAQNKMHVGPLTEDVLNTRGMTEKKHdtlekrtftNLNTF 139
RAQ94616              74 WQAGSLrldergqlllagehENGEQNWRFLGSDILAALQAAEHAGGRVGPATAGLLQARGLTEEATdplhksvvqRLNRH 153
PRJNA61347:EYM_06845  76 GKPQVE---------------------RWLDSRIHMMLWTLWKTKSEAPKDWKTPLLERNFVNEEG---------KLRDE 125
jgi:Igni_0126         77 GRPEAE---------------------RWFDSSIHAAVWSLWRTSAKAPKDWFTPLRERGLVDEEG---------FLTDA 126
Q8TZ95                77 ILEQPP--------------QEWAHD-RWVGSDTVLALKHAALSFV--PERWEELLSERGLSEDGE----------LTKA 129 Methano...
Q5JFF3                71 ELPDVI-----------------------ADTEIIKMMELLEETGKIP-ESWMEKLRERKLADENG----------LTPF 116 Thermoc...
BAF69133              67 NSIEKI--------------DEWKENFKWVSSEVIAMIDAAIKGKNKTTKVTNDELERRGFAKSGE----------LTSA 122

RMA97819             138 AKAVYEIYQ--NAKPRLEISKELASYITGMPTGPA-ETKMLPE------HGRFPLLLESMRLISFSVP--NSDVYTLSGL 206
Q9X0A7               127 AYTLDEIYH--ASHPRLVVNLKVAEYLRKMVEGPG-ESSTLPV------GGDELLQLEAMRMIAFSVP--RSDVYALTGL 195 Thermot...
BAT71239             118 GEELWEIYR--LAKPHLTIDQELAKLVKKLPVGPVrKTGVIDM------DDRQVKFLEAQRLIAFSMP--PADFFTFTGL 187
GCE22002             140 GEAWEDFDQ--RHHPLLEINQDLANGMRHMHPSYT-ARPDLTL------SAEHLSLLEAMDLLTWSSP--DRTTYALTTL 208
RAQ94616             154 GRAWLDFAR--RHRPRLEIDGELANAIQRMIPGYS-GRPAPGL------SGDFIDLLEAMELITWSLP--DGRFYALTAL 222
PRJNA61347:EYM_06845 126 AIELLKVFEpgIRARKIRITRDLGGVLARIAPGPAtTAALKNH------PEDALDLLEAMDVIVYSAP--DGGYYALTRL 197
jgi:Igni_0126        127 AKKLVEQFEpkVRPVKVRVTRDLGWTLARVPPGPAaVAPLSKF------PEEHIDLLEAMGVIVFTSP--DRKYYALTRF 198
Q8TZ95               130 GELVLEAYF--KATPKLYVTQDVAGRIARLPPGPGtLKTFIRYretidiPDNIFHALEAMRLLVISPPadGGRTYTLTAL 207 Methano...
Q5JFF3               117 GKALLEVYR--ETHPVVYLTPEIASFLRGMPKIGT-LDELVTYknsklyGDNIVNALQAMRLLLISPPteKGRAFATTPA 193 Thermoc...
BAF69133             123 ALELFNAYA--ITEPELSIDAKLAEYIRKSPMGPT-DAHYLPI------EGNSKDLLEAMRLIAYSVP--HGDFFTFTEL 191

RMA97819             207 GQAVQKALQTMAPAYE--TVINEDYMYSLLKVLDSGieALSEQEKEILESLALIDDEGELLPAGEALLEVYKLWSEKIYR 284
Q9X0A7               196 GQQIRAALRKGLVVTDe-LILDELILDTVAKAYEGN--QLSDFERNALLERGLIDWTGELHPMAEHLYLAWKIYKKGPYL 272 Thermot...
BAT71239             188 GQKVKEALEKGAQPFP--IAVSVDIMLAVKRAKESPe-HLSENDIVALQAMAYIDENLELLPAGEALYMAYKLYNEGALL 264
GCE22002             209 GQAAYEAVLKEGYPVLd-EVLNKAIMTVLAQFIDQGrdALTPEQLFNLQMLGYVDGEEKITAAGQAAMRAYSLLQQEVEE 287
RAQ94616             223 GEAVYEALRKGGYTLGa-VVLDEPTLKLLALLVDRGseALTADQRERLQELGFMGLDSYLTPAGEAALRAYALLQSERPV 301
PRJNA61347:EYM_06845 198 GRYLRMAIRELRPVAMeyILVNMKIIELVKKLIEGK--ELTDQEKFVLMNLGYM-TVSEPTKAAKLLYKAIEELERGKYW 274
jgi:Igni_0126        199 GRFLREAIRELRPVAMeyVLVNMKIAEMVKKLVEGG--ELTEEEKYWLMNLGYY-RDGKPTRAAKWLYLALKELERGEWW 275
Q8TZ95               208 GREVKYAIEKAIPAMH--LVLSPGIMEDVKAVSEGE----EPEDMERLERLGYA-WKGSLTRAGEHVLRAYEMVGED-FP 279 Methano...
Q5JFF3               194 AKLALKALNMIPVFARa-IVLRKEDFEMLK----------AGKRNAELESMGLADEKGT-TEFGKAIMDTYEAMGRVEEK 261 Thermoc...
BAF69133             192 GQAVKETLTLGGWANEg-SVLDISILESIALVADGE--DVDVDRLMQLEALGYVSDVDTLTKAGEKALEVYRIFKDKTEK 268

RMA97819             285 PVKTFNLETLDEELLIGIEKVWEK-HKENPEIVPTDEEIVHFLLEKPLKEYKHLKEYYGRMLNQAMgyQKKEELNKKWSE 363
Q9X0A7               273 MTPAFQISEDEARLLEVIVKLWKR-HEKEDDVFPEPKQIEKAVDW----------------------------------- 316 Thermot...
BAT71239             265 LTPSIVLSDDDVEVLFAADELWKK-YQQNPEIMPTPTQIREYIA------------------------KVRPAIEKE--- 316
GCE22002             288 PSRTFAITEPELELLATLHSISDP-SSTRPQPPPDKQALHKIFVDRMVQHYQQFIGRYGRDFKGKL--AKKQRAVAMLEQ 364
RAQ94616             302 SVRTFALTEAEVEVLLTLHQLAAR-Q-ENGGPSPDLERLRKTLVEQLAERYREIVGRYGRRLEERS--ALKRRAVELLGE 377
PRJNA61347:EYM_06845 275 ETFTIGLTRVDQWVMKMIDYLWKK-AETNPELKPTKSLIVDWF----------------ERHWKDIgmDEETRKELLFSD 337
jgi:Igni_0126        276 DTFPIGLTRVDEWVLKTIDHLWKK-AENNPELKPTKKLIQYWI----------------EKHRDELgmDEETYKELEFSD 338
Q8TZ95               280 GVPPISIRPSELRLLEIIDHLYRP--DENPNVAPTLKRIKRVLVEE---------------------------------- 323 Methano...
Q5JFF3               262 VLPMYLLED-ELSVLKAIQEIEKK-YETNPDILPTEKEIERRV------------------------------------- 302 Thermoc...
BAF69133             269 PLRSFAIEKEEVETLKTIDRIWKEkYTSNPEETANFDEIKKELVDRKVREYKRILEKYGRRLDEMP--KKKQEIAKKFGE 346

RMA97819             364 LKNIEelfkhfwekgnEWYEKLFDtIKESLYSLEAFNLIKAELDEk---TGK--TVYKFTKHGIEVLKDIKErGVREIKS 438
Q9X0A7               317 ----------------EWKRKDLT-VKLALYNLEGFGLLKSREHKh---GARrtLVYELTSYGEEVLEDQRK-SLRSVTA 375 Thermot...
BAT71239             317 -------------------------VMKILYSLECFGILTSE-EGp---KGR--LVYTFTDWGKKVLADQKE-ARRPISS 364
GCE22002             365 LKDHD-----------KWFNTFWD-LDELLVSLAAFDLVRPERMDq---K----TVYIITPNGQRIVEAVGR-GTNDISA 424
RAQ94616             378 LRSRD-----------EWFDSLWD-LEELIASLEALALVRTESDGe-----R--TLYRLTPYGQRVVEEQQQeQIRAISS 438
PRJNA61347:EYM_06845 338 YT-----------------------VGISLYRLEALELVDSYEEKs---K----LIYQLTDYGKQLLEVIEKgKIVEIPT 387
jgi:Igni_0126        339 YT-----------------------IGLALYRLEAVRLVDSY--Ee---KGK--LVYELTEYGKRLLEVLG--QITEVPA 386
Q8TZ95               324 ------------------YGEADPdPTTDLKELEAHGFVEKTVCDygkeKGK--PIWVLTEEGERLLHGLGA----PVRA 379 Methano...
Q5JFF3               303 ---------------------DVKdLGAILHLLESKELIERRLVKe---K----DTYWLTEWGKEAI------NFGTVSP 348 Thermoc...
BAF69133             347 AKDMV-----------QWFEENFD-LREYLYSLETFGLIQEGVDSk----GR--AVYYVTENGQKVIQDQA--DERSIHS 406

RMA97819             439 TAVKAISITKTQFGVPNYEWYEEAVNEHLVGG-GYPTKAGQLYENLAYNIYRLPHLTRFELMVLHK-IP-EYGMFLNDLF 515
Q9X0A7               376 VGVKSITMTKKEFAAPNMEWYEQARKEGLVSD-AAPTSSGRLYARLSVEAERRPLITNTEMKVLRK-VPyKAGVFIEDM- 452 Thermot...
BAT71239             365 PAVKCITITRKEFSAPGVDWYEEAVEQKLVGS-YGPTKSGTMYADLAVSIDRLPHITDYEMEVLSR-ISdENPLYLKEYM 442
GCE22002             425 TGVKVLTSAITRLHSPADLWVEQARDEGLIGTkGGITKEGHLFADLAEHCTRLPALTRDEAEMLKN-LP----QIINDIA 499
RAQ94616             439 TAVKAVSMAVTRWTGLATSWVERAREEGLVGSgGGVTRAGRLYSWLAEHCPRQPMLTRVEAEVLAN-LP-ETE--PGPFV 514
PRJNA61347:EYM_06845 388 YAIRPLVYADR-GLPPFRSWIEEAAKEGLLGP-GGMGRKGRKLAHLARVVKRRPLLTRMELLVLQKmLPsGQVQKIEELV 465
jgi:Igni_0126        387 HAVKTLVYADK-GIPPFRLWIEEAIRWGLMGP-QGAGTKARVLMWISRRVKRLPLITKLEHLVLQKtLPsRRAEPLEELV 464
Q8TZ95               380 EGVKAVTVSMG-FESPSPEWLEEAHRAGLVSQ-AAITTKGLMAAKIARRVERAPFLTGDEAKLIYR-MP-NGSIDRGKLI 455 Methano...
Q5JFF3               349 DAMKAVTYAES-GDVPIAEWVLKAQEENVVK--AGVTDKGRFYLRLSREIKRKPFITRYDAAILAK-TPrKKYIHRDELV 424 Thermoc...
BAF69133             407 WSVKTLTISNKIFSSPNREWVEEARKERILGT-YEPSSSGLLYEELANG-EKLPFMTRYEMDIFKM-IP-DHGVSCEVIL 482

RMA97819             516 KEFD---ETLKEEVQYAVNKLEARYILDVLPNKAIVLTEAGKLIKKALSGVPE----GIANPINPVLVRILQAIKE---- 584
Q9X0A7               453 --------NLSEEERIALDSLEAKNLVEILPTDVVTLTEAGQLMKRALSAVSD----DVEAPVTPLVIRLLQAIRT---- 516 Thermot...
BAT71239             443 KGD----EEEQRRIRKAIEMLDAKGFVEILPTGIVVLTEAGVYMKRALAGVTS----GFGNPVTPHLVRVLEAIRE---- 510
GCE22002             500 PPAEkktQQDEEKQRWALEKIEARGFIECLVDGQIVRTPIGQLLAKAISGAMH-----LGHPVTPSIVRLVAAIRQ---- 570
RAQ94616             515 SEYQa--SLEGERLAWALDKLEAHGLIDRLADGQIVRTEAGRLLARAVAGATK-----LAHPITPRIVRLLEAMRQ---- 583
PRJNA61347:EYM_06845 466 KKFE-----NPDEARAALYWLEMWGAVNFYDNDYVEITEIGENLKKALVATPP----GIATPVHPHFLRVLEVIKE---- 532
jgi:Igni_0126        465 KRVSa-lGYDEEEVRAAIYWLEMWGALEVYGNGYVELTEIGDMIKHALVATPP----GVATPVHPHFIRVLQAVKE---- 535
Q8TZ95               456 EDVCdryGLEEHQVLESLSKLESRGIVEELLTGGVILTRAGQHLKTAIHRGQTmeilKLRHPITPVATRLLKAVYD---- 531 Methano...
Q5JFF3               425 ALVQdyvGGDEKEIIRAIGEAEAKGFVVELQNGMVKLTELGDKVKTAIENAKLqeivKVKFSVTPTLYNVLKVIYDniet 504 Thermoc...
BAF69133             483 DKTl--hEDEYMHRKEALDKLEAKGFIEILPDGHIIETEYGKLMDEALSGVPE----GFGVPVNPTIYRVVKAIAQ---- 552

RMA97819             585 VGNLYVKERKVRILPKNWEEA-IKKSGVDKETFEKEIAVARLAGYIGKTSLHESALEILEAV 645
Q9X0A7               517 HGGLQMREKRIRINPESWKVV-ERELGVDPETFDDTVNLARISKFITENALTEAGVALLQAV 577 Thermotoga maritima
BAT71239             511 VGTLYEKEKKIRVRPDRWKKV-EKLSGLDAETFAEVLRIARMTKFIGTNSLTQAGYYLLQSL 571
GCE22002             571 VGTLYVKERKVRIVPENWAEV-ERLTGLGPQEFKEARHVARMGQYIGDVTITEAGLDLLMVM 631
RAQ94616             584 VGTLYVKEQKVRLQPEQWKEV-ERLTGLGPQEFLETRHVARMGHYIGEVTLNEAGLEVLEAA 644
PRJNA61347:EYM_06845 533 LGSY-----------EDIAEI-VNRTRLTLGIVKDAIVVAREAKLLGKKDLTGEGELLLETV 582
jgi:Igni_0126        536 LGSY-----------EDLAEI-VNRTRLTLGIVKDALVVAREAKLLGAKDLTGEGELLLEAV 585
Q8TZ95               532 LKREGVSAKKLSKFPKTL----LKRADVTLDQAKKAVGLLRRTKMMSGWKITEAGEELLRAF 589 Methanopyrus kandleri
Q5JFF3               505 FNRIWKEKGEARDYKMEEVDAiRKHLSLSDDEIKKALTMLRELGFLGTKSLTEAGKVLVEAY 566 Thermococcus kodakarensis...
BAF69133             553 TGSMYVKEQKVRIMPENIKEA-IQKSGLSKESFEKAYIAAREAKFLGKNSVNEAGLKMLQAV 613