Conserved Protein Domain Family
NIF

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pfam03031: NIF 
NLI interacting factor-like phosphatase
This family contains a number of NLI interacting factor isoforms and also an N-terminal regions of RNA polymerase II CTC phosphatase and FCP1 serine phosphatase. This region has been identified as the minimal phosphatase domain.
Statistics
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PSSM-Id: 397254
Aligned: 116 rows
Threshold Bit Score: 63.024
Threshold Setting Gi: 149938638
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ESA41793     163 LSLVVDLDQTII------HACIDPTVGEWqkdpsnpnypsvRNVKSFqldDGPrgvannCWYYIKMRPGLEDFLKK-IST 235 Neurospora cras...
Q5KIE0       288 KLLVLDLDYTIV------DTK-----------------------SLL---NGT------LPSSECARPGLHDFLEL-VYP 328 Cryptococcus ne...
XP_001415855 141 KCLVLDIDYTLFd-----HRTT----------------------------AEN--------PSEIMRPFLHEFLSRaYAA 179 Ostreococcus lu...
Q01GE0       143 KCLVLDIDYTLFd-----HRTT----------------------------AET--------PEEIMRPHLHEFLTRaYEA 181 Ostreococcus tauri
Q17FW8       145 RLLVLDIDYTLFd-----HRSA----------------------------AEN--------GAELMRPYLHEFLTS-AYQ 182 yellow fever mo...
Q28EX9       138 KLLVLDVDYTLFd-----HRSC----------------------------AET--------GQELMRPYLHEFLTS-AYE 175 tropical clawed...
Q9SJQ4        49 KLLVLSLSGLLL------HRV------HKk-----------ELRKKP---KNRspdascGPNLVYKRPFAEEFMKF-CLE 101 thale cress
Q8LKU4        20 KLLILDLNGLLAdinedyHNA-HMADA-----------------KVR---GKL------GEISIFRRPYCDDFLNF-CAL 71  sorghum
XP_003722543  57 FLLVLDLNGVLV------ARG---------------------------------------RGSFILRPNVSDFLKF-VFS 90  Leishmania majo...
Q5AYR8       284 LLVILDLNGTLI------YRK-----------------------------TRK------FPPSFSRRVGLDDFLKV-LVE 321 Aspergillus nid...
ESA41793     236 MYELHVYTMGTRAYAQNVARIV----DPDKKl--FGNRv---ISRDEN---------GN----MYA-KSLQR-------- 284 Neurospora cras...
Q5KIE0       329 HYDIVIWSQTSWRWLETKLVEL----DLFNNs--RGYKisfvIDRTCMfpvf--sqrNGqpykHEV-KPLAY-------- 391 Cryptococcus ne...
XP_001415855 180 NFDIFIWSATSLKWIELKMTELg---VLTHNdykIVGL----IDSSAMit-----veTAkygvFNC-KPLGY-------- 238 Ostreococcus lu...
Q01GE0       182 GYDLVIWSATSLKWIELKMTELg---VLTSEs--FKVV----GLIDSTamitvetakYG----LFNcKPLGF-------- 240 Ostreococcus tauri
Q17FW8       183 DYDIAIWSATSMKWIVEKMKLLgvttHPDYKl--VFMLdseaMITVHCp-------vRGv---IEV-KPLGV-------- 241 yellow fever mo...
Q28EX9       176 DYDIVIWSATSMKWIEAKMKELgvstNSNYK---ITFM----LDSAAMit-----vhTPrrglVDV-KPLGV-------- 234 tropical clawed...
Q9SJQ4       102 RFEVGIWSSACELVSSLNILIV----TGPREctdSGYK----TLENRY---------KP----LFF-KDLSK-------- 151 thale cress
Q8LKU4        72 NFELGIWSSRKKENVDSVVNIV----MNE-FkprLLFC----WDLSKCtftg-hktlENkhkpLVL-KELRK-------- 132 sorghum
XP_003722543  91 NFVVAVWTSGLQRSSNPIIDHVf---GNYRDl--LLFM----LFRDACvp-----kpSAenpyGTE-KNLQV-------- 147 Leishmania majo...
Q5AYR8       322 KYKVMIWSSSQPPTVAAVCEQLf--sESHRKk--LVAE----WGRDKLgl------sKS----EYN-TKVQVyktletvw 382 Aspergillus nid...
ESA41793     285 --L-------------F------PVSt--kMVVIIDDRADVWPRNRP-NLIKVSPYdfFkGigDINSGFLP----K-QQG 335 Neurospora cras...
Q5KIE0       392 --Lw------------Asfp-qwSAK----NTIHIDDLSRNFALNPG-EGLKIRAFnkAgSpdGRRDRELI----K-LGT 446 Cryptococcus ne...
XP_001415855 239 --Lf------------AqdwceyDSK----TTLMFDDLSRNFIMNPQ-LGLKIRPFrnA-HtsRATDRELL----R-LSE 293 Ostreococcus lu...
Q01GE0       241 --Lf-----------aKlp--qyTPK----NTLMFDDLSRNFVMNPQ-LGLKIRPFrnA-HthRATDRELL----G-LAR 294 Ostreococcus tauri
Q17FW8       242 --Iw------------Rkys-qySSK----NTIMFDDLRRNFLMNPK-SGLRIKPFaeA-HlnRHKDKELL----K-LTK 295 yellow fever mo...
Q28EX9       235 --Iw------------GkygefyNKN----NTIMFDDIGRNFLMNPQ-NGLKIRPFmkA-HlnRDKDKELL----K-LSQ 289 tropical clawed...
Q9SJQ4       152 --Vfk----------cFkg---fSAS----NTIFIDDEPYKALRNPDnTGLFPMSY----DasNIKDN-LLdpegE-LCS 206 thale cress
Q8LKU4       133 --Lwnmeep--dlpweEgd---ySPS----NTLLVDDSPYKALRNPP-YTAIFPRS--Y-SylNWNDNSLGpg-gD-LRV 195 sorghum
XP_003722543 148 --If-----------dRy-----PHSfhsvNTIIIDDSPDKCS-HPDiALCPIP-F--KdPvaQMQDEGLL----Q-TME 200 Leishmania majo...
Q5AYR8       383 ssKqiqashpgrvnkgKkkgprwDQS----NTVLIDDSRLKAVSEPY-NLIEIPEF--T-NnpNVDESAIF----PkVLQ 450 Aspergillus nid...
ESA41793     336 LLTpSAAatTNgGLAR 351 Neurospora crassa OR74A
Q5KIE0       447 YLI-GIA--ASeSDFT 459 Cryptococcus neoformans
XP_001415855 294 YLE-EIA--SL-DDFS 305 Ostreococcus lucimarinus CCE9901
Q01GE0       295 YVE-AIS--KL-EDFS 306 Ostreococcus tauri
Q17FW8       296 YLK-DIA--DNcNDFN 308 yellow fever mosquito
Q28EX9       290 YLK-EIA--QL-DDLS 301 tropical clawed frog
Q9SJQ4       207 YLE-GLA--KS-SDVQ 218 thale cress
Q8LKU4       196 YLQ-NLA--AA-DDVE 207 sorghum
XP_003722543 201 VLK-EVL--LLdSGVP 213 Leishmania major strain Friedlin
Q5AYR8       451 RLE-ILA--MC-DDVS 462 Aspergillus nidulans
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