Conserved Protein Domain Family
SpoIIM

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pfam01944: SpoIIM 
Stage II sporulation protein M
SpoIIM is on e of four stage II sporulation proteins that is necessary for the forespore inside the mother-cell to be properly internalized through the breakdown of peptidoglycans trapped between the membranes of the septum separating the forespore and the mother-cell. The four proteins working in sequence are SpoIIB, pfam05036, SpoIIM, SpoIIP, pfam07454, and finally SpoIID, pfam08486. D, M and P are in a complex with each other and the complex assembles in a hierarchical manner such that M, which serves as a membrane anchor, recruits P to the septum and P, in turn, recruits D to the septum.
Statistics
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PSSM-Id: 426524
Aligned: 356 rows
Threshold Bit Score: 36.4899
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_009508245   130 AVTLM--IAGMIF---------GGAAMAldpeakavimpfshlldspservakeerragnpgrdrlaGRKATFAGELMTH 198 Opitutaceae b...
WP_015171917    52 GLV----IIGFVA---------AMVFPNlnatqvaiqed-----------------ngtadlvrslfNNPWLFSLTILGV 101 Geitlerinema ...
Q67ND5          25 HTALF--VVGLLF---------GALALRslevetqlelarqisg-------------alqalregeppapgpLLREALFR 80  Symbiobacteri...
jgi:Theco_1942  20 IAVLT--AAGIVF---------GVLASRtltldqqdnlasdla-----------ryaltaeagqmadaGD--TLSDRAML 75 
WP_015843927    20 VAVLF--VVGAIF---------GGLMVNaltleqqqdlaadvn-----------qyirlvndgvtpdaAQ--SFWDSFIF 75  Paenibacillus...
CDC28824        19 VCLSF--LLGTIG---------GAVAANlagrsgeetl--------------------vrflqehltAGGDSSFWYTFWK 67 
CCX39900        19 VCLSF--LLGTAG---------GALLANllpqgqqgql--------------------saflqqalaDGDEIGFAAIFWK 67 
EQB67104       173 FFILL--IIYTFIdpssplassGVKSKSa--------------------------------------FHYWVFFKSILNN 212
Q6KZW0           9 FIIFFvlEIAIYLgvssipynnPGLYNAfkleq-----------------------------ssivsQPFIPMWLSIFPH 59  Picrophilus t...
EQB71475        19 fLVVFlvEIGIFIaisslsihnQVLLSAfkneq-----------------------------qsivtLSLPDMILEIFPH 69 
WP_009508245   199 NTKV-TIFLMALG-I-TW-GVGTVVLL-FYNGVI--LG----------AVIVDYVLGgq---tvFLAGWLLPHGS---VE 255 Opitutaceae b...
WP_015171917   102 NLATgALWIVLPSlIvPFaGIATF----AYKTFT--LGlvmapttktmAV------------------ALIPHSLtilIE 157 Geitlerinema ...
Q67ND5          81 QART-VALMWVLG-VsLV-GSVAVMALpLVRGFT--SGf---------AVAYLTAELgar-gvlLAAAGHLPQTV---LE 142 Symbiobacteri...
jgi:Theco_1942  76 HGKW-LLAVWLLG-VtVI-GAPFVLVLdFLKGVL--IGf---------SLGVLVQAYgwk-gmlFALAAMVPGNL---LV 137
WP_015843927    76 HGKW-LFLLWFLG-IsVV-GIPFVLALdFLKGAL--VGf---------AVGSLISQHawk-gvmFSLASVAPPNL---IV 137 Paenibacillus...
CDC28824        68 YMKY-DLLIWAGG-WlSM-GVFISGCVcLFRGIS--LGf---------TAAMLMASYggk-gvwLTILGILPQNL---LL 129
CCX39900        68 YLKY-DIIIWLGG-WmQL-GLFFAGAAfLFRSVC--VGf---------TSAMMMAAYgmk-gvlLSATAFLPQNL---LL 129
EQB67104       213 NLTL-DISEYMIG------------------GFSlfVGtfielfssniYEAVIISSMdsthgfsSFVKFILPQFF---PE 270
Q6KZW0          60 NLLI-ATIEFIVP-V--I-GVIFFVYSiTETSLVlaAEg---------TVHYHVSGLf-----lAISLFLLPDTW---LE 117 Picrophilus t...
EQB71475        70 NLLV-ATIEF----IpVI-GQLFFLLSsIETSIIisIE----------GTSLHTSGLv-----vFFSLAILPHTW---LE 125
WP_009508245   256 IPAVLIGGQAGLVL-------AGALlgseggagrrgglrrPGLRMRLRAVTPDLVTLCLGAGV---MLVWAGVVEAF 322 Opitutaceae bact...
WP_015171917   158 LQAYALLMFGAYIL-------GRSWvrp----------atIGTRNHRQGYVRGLQQLGWLSLStlpLFIVGAIWEAF 217 Geitlerinema sp....
Q67ND5         143 VPGVILAASASVGF-------AVEVltswrv------------rrrlsgYYDALARYSNTLLCaavLLAAAALVEGY 200 Symbiobacterium ...
jgi:Theco_1942 138 LPALLFASVSSVAF-------ALHVfryrlv-------------qpsgsLREPLLAHTSAALIllaVMTGGAFIEAY 194
WP_015843927   138 VPAIMITSVAAITF-------STYViknrll-------------qqkgtLAPQIAAFTSTALLmllLLAGASLLEAY 194 Paenibacillus sp...
CDC28824       130 IPAYVAMTTVAVYYlfaw------------------geegSRKGASKREKRRRQTEYCILLVAsilPIVVASGVEVg 188
CCX39900       130 IPCYILMMSACVYYllsw-------------------qeeGGKRTLKREKRRKQLEYCILFGGsvlLLAAASGVErm 187
EQB67104       271 TMGYVFGMSIALIItdiilsfIQSLvk------------nEKSEYFTKRVHDLSYNLVFYFLLsvsLLIVGALIESs 335
Q6KZW0         118 IPSYAIASAMNIYI-------IYYL---------------ITLRKRNYSTKRLFTRLIEMYLFivlELAIAGAVETW 172 Picrophilus torr...
EQB71475       126 LPSYAVATSTSIYL-------IYLL------------------AKRGQILHSNIMKVVYMYLFvvlELAIAGTFESt 177
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