Conserved Protein Domain Family
SpoIIM

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pfam01944: SpoIIM 
Stage II sporulation protein M
SpoIIM is on e of four stage II sporulation proteins that is necessary for the forespore inside the mother-cell to be properly internalized through the breakdown of peptidoglycans trapped between the membranes of the septum separating the forespore and the mother-cell. The four proteins working in sequence are SpoIIB, pfam05036, SpoIIM, SpoIIP, pfam07454, and finally SpoIID, pfam08486. D, M and P are in a complex with each other and the complex assembles in a hierarchical manner such that M, which serves as a membrane anchor, recruits P to the septum and P, in turn, recruits D to the septum.
Statistics
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Aligned: 415 rows
Threshold Bit Score: 29.9305
Threshold Setting Gi: 524101653
Created: 3-Jun-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_009508245     130 AVTLM--IAGMIF---------GGAAMAldpeakavimpfshlldspservakeerraGNPG-------------RDRLA 185 Opitutaceae...
jgi:GEI7407_1869  52 GLV----IIGFVA---------AMVFPN------------------------------LNATqvaiqedngtadlVRSLF 88  Geitlerinem...
jgi:Cphy_2594      4 AMVLF--FASVIL---------GCIFSKvsqgllqnsvdslns---------------------------ryfntiksme 45  Lachnoclost...
EQB67104         173 FFILL--IIYTFIdpssplassGVKSKS---------------------------------------------------A 199 Thermoplasm...
EQB65803          17 FFILLvlEFLIYIivssipfkdPSLLASf-----------------------------KSEQ-------------SSITS 54  Thermoplasm...
EQB71475          19 fLVVFlvEIGIFIaisslsihnQVLLSAf-----------------------------KNEQ-------------QSIVT 56  Thermoplasm...
WP_022024130      18 friILcsGISLVL---------GAVLGH---------------------------------------------------- 36  Clostridium...
CDE54912          35 IILLF--LLGVTA---------GTFFINif---------------------------cKGGYeelgtystyfidrFSECT 76  Roseburia s...
CCX39900          19 VCLSF--LLGTAG---------GALLANllpqgqqgq---------------------------------lsaflqqaLA 54  Firmicutes ...
CDC28824          19 VCLSF--LLGTIG---------GAVAAN---------------------------------LagrsgeetlvrflQEHLT 54  Firmicutes ...
WP_009508245     186 GRKATFAGELMTH-NTKv-TIFLMALG-----------------I-TW-----------GVGTVVLL-FYNGVI--LG-- 229 Opitutaceae...
jgi:GEI7407_1869  89 NNPWLFSLTILGV-NLAtgALWIVLPSl----------------IvPFa----------GIATF----AYKTFT--LGlv 135 Geitlerinem...
jgi:Cphy_2594     46 inygdFFRYIFTS-KLKp-FFLFWTLS-----------------LtFL-----------GLPYMGWYlLSRGFQ--VGy- 92  Lachnoclost...
EQB67104         200 FHYWVFFKSILNN-NLTl-DISEYMIG--------------------------------------------GFSlfVGtf 233 Thermoplasm...
EQB65803          55 QSIPVMFMDIFLN-NFRv-ASIEI--------------------IpII-----------GPFFYLASgIATALIisLE-- 99  Thermoplasm...
EQB71475          57 LSLPDMILEIFPH-NLLv-ATIEF--------------------IpVI-----------GQLFFLLSsIETSIIisIE-- 101 Thermoplasm...
WP_022024130      37 ----LLRTELFADiNAEf-EQILLALDtksihypslfrlctstqFkQLfllcffsltnaWVFYLTFYcLYTGFR--CG-- 107 Clostridium...
CDE54912          77 VNKKDLFFYSFAE-RSRe-ILVLLILA-----------------FtTL-----------GNLVCNVYlLYKGLT--VGi- 123 Roseburia s...
CCX39900          55 DGDEIGFAAIFWK-YLKy-DIIIWLGG-----------------WmQL-----------GLFFAGAAfLFRSVC--VGf- 101 Firmicutes ...
CDC28824          55 AGGDSSFWYTFWK-YMKy-DLLIWAGG-----------------WlSM-----------GVFISGCVcLFRGIS--LGf- 101 Firmicutes ...
WP_009508245     230 --------AVIVDYVLGg---qTVFLAGWLLPHGS---VEIPAVLIGGQAGLVL-------AGALlgseggagrrgglrr 288 Opitutaceae...
jgi:GEI7407_1869 136 mapttktmAV------------------ALIPHSLtilIELQAYALLMFGAYIL-------GRSWvrp----------at 180 Geitlerinem...
jgi:Cphy_2594     93 --------LMMTLWMHYgm-kgGLLYLTYLFPQEL---IFVPVVLISIKNCFALymeanheSTAG--------------- 145 Lachnoclost...
EQB67104         234 ielfssniYEAVIISSMdsthgFSSFVKFILPQFF---PETMGYVFGMSIALIItdiilsfIQSLvk------------n 298 Thermoplasm...
EQB65803         100 --------GGSYNISGL-----FVFITLLLFPHSW---LELPSYAVAVSISIYL-------TYTL--------------- 141 Thermoplasm...
EQB71475         102 --------GTSLHTSGL-----VVFFSLAILPHTW---LELPSYAVATSTSIYL-------IYLL--------------- 143 Thermoplasm...
WP_022024130     108 --------LLLSFCLTHnvhsgFFDFLCFLLPHCL---LYIPAYLLLINMLQQI-------------------------- 150 Clostridium...
CDE54912         124 --------LISVYVMQYgs-ggMLLYGISIFPHYI---TYIVMIIILVSFVKEI-------QKEVrvenvsk-------- 176 Roseburia s...
CCX39900         102 --------TSAMMMAAYgm-kgVLLSATAFLPQNL---LLIPCYILMMSACVYYllsw-------------------qee 150 Firmicutes ...
CDC28824         102 --------TAAMLMASYgg-kgVWLTILGILPQNL---LLIPAYVAMTTVAVYYlfaw------------------geeg 151 Firmicutes ...
WP_009508245     289 PGLRMRLRAVTPDLVTLCLGAGV---MLVWAGVVEAFFSQ 325 Opitutaceae bacterium TAV5
jgi:GEI7407_1869 181 IGTRNHRQGYVRGLQQLGWLSLStlpLFIVGAIWEAFslr 220 Geitlerinema sp. PCC 7407
jgi:Cphy_2594    146 -------LQNVLLLKKYIKLIIIlivCILIGACMEAFVgs 178 Lachnoclostridium phytofermentans ISDg
EQB67104         299 EKSEYFTKRVHDLSYNLVFYFLLsvsLLIVGALIESslgi 338 Thermoplasmatales archaeon E-plasma
EQB65803         142 IKIKEGKEKLKYRLIKSLLLYGFvavELAVAAIFESieiy 181 Thermoplasmatales archaeon E-plasma
EQB71475         144 ---AKRGQILHSNIMKVVYMYLFvvlELAIAGTFESteiy 180 Thermoplasmatales archaeon A-plasma
WP_022024130     151 ----RDQKAKKQSLLQGLPILLLsicLLFAGCLCEAFINP 186 Clostridium sp. AM49-4BH
CDE54912         177 --keiasriMKKKLGIYLRCLLLifaLNILTAYLEAFVnf 214 Roseburia sp. CAG:303
CCX39900         151 GGKRTLKREKRRKQLEYCILFGGsvlLLAAASGVErmlll 190 Firmicutes bacterium CAG:102
CDC28824         152 SRKGASKREKRRRQTEYCILLVAsilPIVVASGVEVglip 191 Firmicutes bacterium CAG:466
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