5HZZ


Conserved Protein Domain Family
PRA-PH

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pfam01503: PRA-PH 
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Phosphoribosyl-ATP pyrophosphohydrolase
This enzyme catalyzes the second step in the histidine biosynthetic pathway.
Statistics
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PSSM-Id: 426294
Aligned: 37 rows
Threshold Bit Score: 64.5624
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5HZZ_B           19 LHEFHRAIGAATPERPTPPPPELLRLRQTLLDEASAEVRAeidhllarqaageALSag---------------------- 76  Deinococcus ...
Q9CHJ4          296 VKDFHRLMDGKTQEIPKAFSPTEASFRADFKVEEIVEFLY-------------ASAdgnqekftelvnnlhqa--vdkaa 360 Lactococcus ...
Q8DSF8          302 VKDFHQLMDGETCEIPRIYDIVEGGHRSAFKAEEIVEFLY-------------ATSngdkeefaqalarlhka--vdkaa 366 Streptococcu...
Q5M2T0          297 VKDFHHLMDGSTTDMPRVYGIEEASHRSDFKLEEIVEFLY-------------ASSggdkrvfgqavldlhaa--ldkaa 361 Streptococcu...
Q8DY16          297 VKSFHLLMDGETIETPRLYDSKEAGFRSDFKVEEIVEFLY-------------AASqgnqkvfdqsirnlhla--idkar 361 Streptococcu...
bgi:05SSU0347    16 VKDFHFLMDGETQELPSVYDGQTALYRAGFKLEELVEFLH-------------AASesevefhdfiqqlhqdl---dtaa 79 
Q8DNC5          305 VKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR-------------AASpseedfgqavsqlhqal---dkaa 368 Streptococcu...
Q5HMX0           81 VKKFHETFGHPVAEVPQPISKERAVQRADYLVEELVEFLW-------------SSVagneheteklvdelihsihkaknk 147 Staphylococc...
jgilanl:CHU2001  10 VAEFHRTFKHPILDTPAIPAIERAKLRVALLAEELKELEE-------------AIAqn---------------------- 54 
Q0VSG3           13 VAEFHRAFSLPVEPQPVVPDDATVRLRLALLLEEFYELVE-------------ATCqevsegqrkflmtla------qar 73  Alcanivorax ...
5HZZ_B           77 -----------dLAPLAHELADLLYVTYGALDQLGI--DADAVFAEVHRAN 114 Deinococcus radiodurans R1
Q9CHJ4          361 nkvtlkehnedsLTGQVDAMIDLLYFTYGSLVLSGI--DPYEIFNAVHRAN 409 Lactococcus lactis subsp. lactis
Q8DSF8          367 ekvlskphpetpLVGQVDALIDLLYLTYGSFVLMGV--DPKPFFDTVHEAN 415 Streptococcus mutans
Q5M2T0          362 lkvsskehsestMVGQVDALTDLLYLTYGSFVLMGV--DPKPFFDTVHEAN 410 Streptococcus thermophilus LMG 18311
Q8DY16          362 dkviskdhpetpLVGEVDALTDLLYLTYGSFVLMGV--DPKPLFDTVHEAN 410 Streptococcus agalactiae serogroup V
bgi:05SSU0347    80 akvsgkrgfgvsMQDQVDALLDILYFTYGSFVLMGV--DPEPIFQIVHTAN 128
Q8DNC5          369 gkvakktpaqqdLIGQVDALIDTLYFTYGSFVLMGV--DPERIFDIVHQAN 417 Streptococcus pneumoniae R6
Q5HMX0          148 cfnkgefpkeeiLLNQTDALNDINYINYGSIVETGV--NPKPIFEIIQKAN 196 Staphylococcus epidermidis RP62A
jgilanl:CHU2001  55 -----------dIVEAADALCDLQYVLAGAVLEFGLgeKFKDLFDEVQRSN 94 
Q0VSG3           74 eqleelegfqvdLVEVADALTDINYVTYGAGHTFGI--DLNACCKEVHRSN 122 Alcanivorax borkumensis SK2
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