2ARY,2P0R,6BJD


Conserved Protein Domain Family
Peptidase_C2

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pfam00648: Peptidase_C2 
Calpain family cysteine protease
Statistics
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PSSM-Id: 459889
Aligned: 152 rows
Threshold Bit Score: 278.231
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2ARY_A         47 FRDEAFPPVPQSLGYkdl-----gpnSSKtyGIKWKRPTELLS----------NPQ-FiVD-GATRTDICQGALGDCWLL 109 
XP_002663893  526 FVDDSFPPGPRSVGfpen----dsvqQRI---KKWLRPHEINCnnfk--drgvKWSvFrt---pRPSDILQGLLGNCWFL 593 
CAF92120        5 FVDDSFPPSPKSIGfppd----dgvqHRV---KKWLRPGEISScnlr--eqaaEWSvFcs---pRPSDIQQGLLGNCWFL 72  
EKC20180      502 FVDDSFPPAPTSVFlnen----kpftKSY---IQWLRPTEIAAprhg--dekvKWAvCrt---pLPDDISQGLLGNCWFL 569 
EFX89537      382 FVDDSFLPTGRSLHnst---------qeG---VQWLRPSQIVSsaa----shvKWAvFrt---pLPSDISQGILGDCWLL 442 
XP_001945127  366 FVDDSFPPAAKSLYytek-----hesCRV---TQWLRPESIICseld---kesCWTvFrk---pKPSDIIQGVLGNCWLL 431 
XP_001018608   95 FTDSEFPAGITQLVGenishsntitiqkdqnDIVWKRSTEF-Lk--------iQKSiF-GKnGIQIHKIKQGTLKNCYLL 164 
EGR29348      276 YDDRDFPPDRNSIAPpdylg-eyrdvVNN----KWRRLKECLP----------NYKlFlg--nIEPNDIQQGALGDCYLL 338 
KAE9444158    613 FVDDSFPPAPKSLYynss----evkdNRV---VHWLRPHQINTdcd----snlSWAvFrt---pLPSDISQGVLGNCWLL 678  Apolygus lucorum
FAA00210       76 FVDDQFPPTENALYfpss-----ssrPNK---CQWLRPQQITFssndtdwrnrEWSvFsn---pSPTDIKQGVLGNCWFL 144  vase tunicate
2ARY_A        110 AAIASLTLNDTLLHRVVPHGqsfqNgyAGIFHFQLWQFGEWVDVVVDDLLPI----KdgKLVF--VHSAEgnEFWSALLE 183 
XP_002663893  594 SALAVLAERPELVERVMITRs---IcqEGAYQVRLCKDGMWTTVLVDDMLPCdeygF---LLFsqAQR-R--QLWVALIE 664 
CAF92120       73 SALTVLAERPELLERVMVTRw---LcpEGAYQVRLCKDGSWTTVLVDDMLPCddsdH---LLFsqAQR-K--QLWVPLIE 143 
EKC20180      570 SALAVLAERPELVESIILTKd---YcpQGAYQVRLCKDGKWQIVLIDDLLPCdhhkR---LVFsqAKR-K--QLWVPLIE 640 
EFX89537      443 SALAVLAERDELVQNVMVTRe---VcnEGAYQIRLCKDGMWRTVLVDDLLPCdqrgH---LLYsqAKR-K--QLWVPLIE 513 
XP_001945127  432 SALTVLAEREDLVRHVMVTKd---YcqQGAYQVRLCKDGKWTTVLVDDLLPCdhrgN---LVYsqAKR-K--QLWVPLIE 502 
XP_001018608  165 SSLSCLAERPKRIAKLFKSRl---IsrYGLYSVFLYVNGEQREVIIDDLFPVyhqtG--LFLFggQLK-Q--DLWILLVE 236 
EGR29348      339 STIAAISEYPNRIKRIFVSQq---EnnVGVYAVKLVWRGELKEVIVDDYVPVdrqgN---PYFlkSKG-A--EAWVIILE 409 
KAE9444158    679 SALAVLAEREDLVRKVMVMRe---YcpQGAYQVRLCKDGRWITVLVDDLLPCdkrgN---LVYsqAKR-K--QLWVPLIE 749  Apolygus lucorum
FAA00210      145 SALAVLAERPDLLKRVMVTKn---YnkEGVYVVRLCKAGVWQTVFVDDLLPCdekrR---LIYs-hARGK--QLWVPLVE 215  vase tunicate
2ARY_A        184 KAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYElr--------------kAPSdLYQIIL-KALErGSLLGcsidissv 248 
XP_002663893  665 KALAKLHGSYFALQAGRAIEGLATLTGAPCESLMlqvsstn---preepidTDL-IWAKMLsSKEA-GFLMGascgggnm 739 
CAF92120      144 KALAKVHGSYFSLQAGRAIEGLATLTGAPCESLAlqlsatn---pkeepidPDL-TWAKMLsSKEA-GFLMGascgggnm 218 
EKC20180      641 KAMAKLHGSYESLVAGKCLEGLATLTGAPCDNIElqpgpq------keeidPNL-IWAKLLsCRES-RFLMGascgggnm 712 
EFX89537      514 KAMAKIHGGYGALVSGRSIEGLASLTGAPCESISlqpstngsnreeaevldEDL-IWARLLsSRTA-GFLMGascgggtm 591 
XP_001945127  503 KAIAKLHGCYEALVSGRAIEGLATLTGAPCESVPlqpssvp----tedeldRDL-IWAQLLsSRLA-GFLMGascgggnm 576 
XP_001018608  237 KAWAKIHGGYMYLDMGTMREALHDLTGAPCDNYFlene-------------kedeIWILITqALQK-GYCITcgtk--si 300 
EGR29348      410 KSWAKLHKCYHFIDGQLTKEALHDFTGAPTRSFptd-------------rnQNE-LWQKILqADQK-QYIMTsgtygedt 474 
KAE9444158    750 KAVAKIHGCYEALVSGRAIEGLATLTGAPCESVPlqpsslp----sedeldKDL-IWAQLLsSRQA-RYLMGascgggnm 823  Apolygus lucorum
FAA00210      216 KALAKLHGCYEALQAGRSIEGLATLTGYPCESLAlqqscp------eteveEDM-VWVKLLsSMEA-GYLMGascgggnm 287  vase tunicate
2ARY_A        249 ldMEAit----------fkKLVKGHAYSVTGAKQ-VnyrgqvVSLIRMRNPWGEvEWTGAWSDSSSE-WNNVDP---YER 313 
XP_002663893  740 k---------vddavyeslGLRPRHAYSILDVRD-Vq----gYRLLRLRNPWGRfSWNGSWSDEWSD-W---PQ---HLR 798 
CAF92120      219 k---------vddleyeclGLRPRHAYSVLDVRV-In----rHRLLQLRNPWGRfSWTGPWSDHWPN-W---PP---HLK 277 
EKC20180      713 k---------tedkvyeekGLRPRHAYSILDVKD-Id----gNRLLRLRNPWGRfSWNGDWSDDSAR-WANIST---RAK 774 
EFX89537      592 k---------ideeeyrqkGLRPRHAYSLLDVLD-Fssk-ggPRLLRMRNPWGHfSWRGDWADDSKL-W---NP---ELR 653 
XP_001945127  577 k---------vdedayqnkGLRPRHAYSVLDVRD-Id----sHRLLKLRNPWGHfSWNGDWSDDSDM-W---SE---KLK 635 
XP_001018608  301 nnKLLpnntrmqdhilnemGLVSSHAYSLLGAYI-Leda-skTKIIKLRNPWGKdEWNGKFSRKDEKfW---ESinkELK 375 
EGR29348      475 g---------gsgdpkqklGLVSGHAYSLIGASE-InvdgqtHKLVQVRNPWGEfEWNGKWNDNDPI-W---NRvsqSDK 540 
KAE9444158    824 k---------vdeeeyqtkGLRPRHAYSVLDVRD-Lng---gIRLLRLRNPWGHySWKGDWSDDSPI-W---TP---QLR 883  Apolygus lucorum
FAA00210      288 d---------tndeeynqiGLRPRHAYSVLRVTseYnik-fiFRLVQLRNPWGHfSWKGDWSNESVL-WQQ-NP---QLA 352  vase tunicate
2ARY_A        314 DQL---RV-KmEDGEFWMSFRDFMREFTRLEICN 343 
XP_002663893  799 HELm-aHg-S-SEGVFWMEYGDFIKYFDSVDICK 829 
CAF92120      278 RELc-tQr-A-EDGLFWMDFSDFIRLEMFGKASE 308 
EKC20180      775 QDLm-lYg-H-TSGVFWMALDDVLKYFDSVDICK 805 
EFX89537      654 AICm-pHg-D-VEGVFWISFQDTLVFFDCIDVCK 684 
XP_001945127  636 IMLm-pDg-C-CEGVFWISYDDVLKYFDCIDICK 666 
XP_001018608  376 KKLgyqKSkD-DEGIIFMQFEDFFKNFADLQVCM 408 
EGR29348      541 NRIq-fTKe--DDGTFFIDYQSLIEHFDAVQICY 571 
KAE9444158    884 EVLm-pHg-A-SDGVFWISFEDVLKYFDCIDICk 914  Apolygus lucorum
FAA00210      353 NQLf-qRn-A-DNGTFWMCLEDMMKYFDSVDICK 383  vase tunicate
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