15791250 151 IvgwggaiaasgggggwtwaPAWSSAVFPGTEIVPVVAVGgaLLAAwsgasahagfgaegrqagayalvgAVVVGTLSVL 230 Halobacterium sp. N... 15594562 27 Ek------------------LIKGKEKWVNLISKDIKLKI--IKYLdqee----------------niiqTIEKTEGALA 70 Lyme disease spiroc... 1709881 332 Vk------------------KIKVNNINERSLFFKERLQS--VVWI------------------------KLNYFLKIFQ 367 Mycoplasma genitalium 20095124 279 tgvivlayryrrrtgrirvrkrkshharLNPVIVSKLMTG--LMVL------------------------AGVIAAAALV 332 Methanopyrus kandle... 2501387 332 Vk------------------KITAANVEQRATFFKERMQT--NHLN------------------------KVYTSWKILQ 367 Mycoplasma pneumoniae 15679722 1 -----------------------MSFRIISPKTSQKIMTG--IFWA------------------------SGIVTVLILL 31 Methanothermobacter... 15901902 1 --------------------------------MSKYLLKL--LVYC------------------------FSALTFGSLF 22 Streptococcus pneum... 15644018 1 --------------------------------MRKDLIAS--YVFR------------------------AVSYVAFAVV 22 Thermotoga maritima 15600843 1 -------------------mTMDRVKLKQARVLKDNILRT--FIWI------------------------SAALTVGFLF 35 Vibrio cholerae 22125298 205 lnqqfealrlqkkrlqiagdldsksqdridaelgelqrrhqtlidklrslqtekhrytllwqdmngqihplplseinraw 284 Yersinia pestis KIM
15791250 231 VLLVGFVVsKGITPVLTGasltggtlgLPFVDAAVPWPTLpfvt-nqtGglyvtiPGVFPALVGTLWLVFGAIVAAVPLG 309 Halobacterium sp. N... 15594562 71 IVPWHYFQnFKAPFIKMHyidkssplnLNFILSIPRDSGA--------Y------GGISYLILNTFYVILLTTAISICIG 136 Lyme disease spiroc... 1709881 368 ELICTFLA-FGFVLAILLf---------VFINGSVAINNNgstvfsfeA------DSTGRALVNTLVIILITITITFPLA 431 Mycoplasma genitalium 20095124 333 GITGYIFA-NGVGALSWN----------ILFGPINIGDPVh--------------SSLYPALLGTLALMFYSTVFAALIG 387 Methanopyrus kandle... 2501387 368 EIFCAVLA-FGFVLGILLf---------VFINGSQAIQRSgstvfsfgV------DTTGRALVNTLVIILVAIGITFPIA 431 Mycoplasma pneumoniae 15679722 32 IIIGYILM-KGLPAVN-----------LEFLLSEPVDSGR--------A------GGIAPMIVSSLYVTLLAGIIATPLG 85 Methanothermobacter... 15901902 23 LIIGFILI-KGLPHLSLS-----------LFS--WTYTSE--------N------ISLMPAIISTVILVFGALLLALPIG 74 Streptococcus pneum... 15644018 23 VIMFVLVLaGGVKYFSP-----------SFFLDYPKNGMTe--------------GGIFPAILGSFYLMVLTFLISIPLG 77 Thermotoga maritima 15600843 36 WIIWYILS-NGLQHVNWK-----------FITDNYTHTGD--------E------HGIFPMIVSTVYMVVASIAVAAPIG 89 Vibrio cholerae 22125298 285 ypndmsfgqklrhwAAQTk---------KFLTDNPYNASS--------E------GGVFPAIFGTVLMVILMSIVVMPLG 341 Yersinia pestis KIM
15791250 310 IGAAVFLTEYA-ERGRFTQLVEVATNGLWSTPSIVFGLFGLAFLVPRLSG----------GNSILVG-------QLVLGC 371 Halobacterium sp. N... 15594562 137 IGTGIMLAEYT-SSKIFYKILSMSVDILSSIPAIIFGLFGLIFFVPILG------------IGILSG-------AITSSL 196 Lyme disease spiroc... 1709881 432 LLIAIWLNEYN-NSKVVKNVFNFVIDSLSSMPSIIYGLFGLSFFLRVLQLsag----ganGTSLIAG-------ILTISV 499 Mycoplasma genitalium 20095124 388 IPTALYLAEFA-GDTAFTRAVRFAIDTLAGVPSIVYGLFGATLFVVYMKM----------GYSVLAG-------ALTLAV 449 Methanopyrus kandle... 2501387 432 LLIAIWLNEYT-KSRIAKNTFSFVIDSLSSMPSIIYGLFGLSFFLRTLQLsag----ganGTSLMAG-------ILTISV 499 Mycoplasma pneumoniae 15679722 86 VGAAVYMTEYA-TEERIVKLIKFGAETLASIPSIVFGLFGLSFFVVFLGl----------GWSILSG-------GLVLAL 147 Methanothermobacter... 15901902 75 IFAGFYLVEYTkKDSLCVKIMRLASDTLSGIPSIVFGLFGMLFFVVFLGF----------QYSLLSG-------ILTSVI 137 Streptococcus pneum... 15644018 78 IFTGVFLSEYG--NNVIAKWIDISLTALSGIPSVVYGLFGLAFFCVALQF----------GTSMLAA-------ALTLSL 138 Thermotoga maritima 15600843 90 IMTAIYLTEYAkVGSRLVKIIRFCTESLAGIPSIIFGLFGMTFFVAILGL----------GFSILSG-------ALTLSI 152 Vibrio cholerae 22125298 342 VIAAVYLHEYA-GKNWLTRLIRISVVNLAGVPSIVYGVFGLGFFVYLIGGsldklfyaesLPNPTFGtpgvlwaALTLAL 420 Yersinia pestis KIM
15791250 372 MLLPLVLLTCREALLAVPDAHRDASAALGVTKWQTIRSVVVPAAMPGTITGVILGVGRIAGETAPLLLVFGGAPypsNTP 451 Halobacterium sp. N... 15594562 197 MILPMIVKTTEEAFKTIPKSYKYASFALGANKTETIIKVMVPAAIPGILTGIVLAIGRALGETAVLLFTMG------TNL 270 Lyme disease spiroc... 1709881 500 VILLFLIRTCQQALNNVSWDLRISAFALGISKREVIFKIVLPSALKGLIVALILSINRIIAETAPFFITSGLSSsnlFHL 579 Mycoplasma genitalium 20095124 450 MNLPVMVRTAEEAFRSVPREYVEAARGMGASWFHVVRDVLLPMAKPGITAGITLSMCRAAEEAAPIILTAVMIG---LIS 526 Methanopyrus kandle... 2501387 500 VVLPFLIRTCQEALNNVSWDLRVSAYALGVSKREVIWKIVLPGALKGLIIALILTINRIIAETAPFFITAGLASsnlFDL 579 Mycoplasma pneumoniae 15679722 148 MALPTIFQVAQVSVETVPQSYREGSLALGATKWETIYRVVIPAAIPGITTGVILGMARAISEAAAVMFVVG------SAL 221 Methanothermobacter... 15901902 138 MVLPVIIRSTEEALLSVSDSMRQASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTST-----N 212 Streptococcus pneum... 15644018 139 MTLPVIASSTRETLKAIPVEIREAALALGATKEEVIFKVLLPAARKGIITAVLVGGGRALGETAPVLLTGAVF----YST 214 Thermotoga maritima 15600843 153 LILPVIIRTTEEALMAVPQTYREGSYGVGASKIYTIRRLILPSAMPGILTSVILSIGRVIGESAPVFLTAGMVA-----R 227 Vibrio cholerae 22125298 421 LTLPVVIVATEEGLARIPTSLRQGSQALGASKAETLWHIVLPMAAPAMLTGLILAVARAAGETAP-LMLVGVVK---SAP 496 Yersinia pestis KIM
15791250 452 DVLGSFsltaqppFVtndallaPASALPYQLYTTITAGVFPkdEFTtaAFGWGTALVLLAVVIGLYAVGIASRRYFRRKL 531 Halobacterium sp. N... 15594562 271 GLATNL-------NE-------PSRTLTVHLLMLFQEGH------L--DKGFGTASILVIMVLIINLTSKFLINKLYRIK 328 Lyme disease spiroc... 1709881 580 SLPGQT-------LTtriygqlFSINSNAISVMLETSLVSVv--FL--ILLIFFSSYLIPSLFLLNKQKWLVIKSKFQSF 648 Mycoplasma genitalium 20095124 527 TNPFVHvl-------------qPTDALAFRIYLIAKEYLMEp-GAR--ATAFAAATVLVAVTLGLNLLAIYMRDKFERKI 590 Methanopyrus kandle... 2501387 580 SLPGQT-------LTtriygqlFSTNSTAVDVMLETALVSIv--FL--MFLIFLSSYLIPYLFSFNKQKWLQIKSKLQlw 648 Mycoplasma pneumoniae 15679722 222 SMPVSI-------FD-------PGRPLPLHLYVLATEGIS-----L--KNAYGTAAVLVIIVLLITVLTNTLVDRYRRKM 280 Methanothermobacter... 15901902 213 tpss---------------lmsSGRSLALHMYMLSSEGLHV-------NEAYATGVILIITVLMINTLSSLLSRKLVKGA 270 Streptococcus pneum... 15644018 215 QLPKSLl--------------sPVMTLPTHIYYITAAYGES---AQ--WMAKGTAAFLMIVVALIYGTAFFLRRRKNGAH 275 Thermotoga maritima 15600843 228 ipds---------------lldSGRTLTVHLYKLTTELFTIe--EW--NQAYGTATVLIVVVLLINMITKLIAKRFNTAT 288 Vibrio cholerae 22125298 497 VLPVDG-------IFpflhlerKFMHLSFQIYDMAFQSPNVe-AAR--PLVFATALLLVIIVVGLNLAAMGIRHHLREKY 566 Yersinia pestis KIM
Jiyao W et al.(2023). "The conserved domain database in 2023.",