4EVQ


Conserved Protein Domain Family
PBP1_RPA0668_benzoate-like
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cd20014: PBP1_RPA0668_benzoate-like 
type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the active transport of lignin-derived benzoate derivative compounds, and its close homologs
This group includes RPA0668 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0668 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Links
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Statistics
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PSSM-Id: 380667
Aligned: 31 rows
Threshold Bit Score: 356.546
Created: 14-Dec-2017
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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ligand bindingdimer interface
Conserved site includes 13 residues -Click on image for an interactive view with Cn3D
Feature 1:ligand binding site [chemical binding site]
Evidence:
  • Structure:4EVQ; Rhodopseudomonas palustris solute binding protein of ABC transporter (RPA0668) binds 4-hydroxybenzoate, contacts at 4A
Download Cn3D for Viewing 3D StructureScroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                   #                                                         ###     
4EVQ_A     18 KVGLLLPYSGtyaPLGEAITRGLELYVQsqggklgGRSISFVKVDDesapPKATELTTKLIQseKADVLIGTVHSgvAXA 97  Rhodopseudomonas p...
ADD43787   37 DVGLLTPLSGalkEVGADAKDAFDRYIDvndgklgGRKINLSIRDEgddpKTSLPSAKKLMQddNVDVIVGAASSanYIA 116 Stackebrandtia nas...
SCL73590   41 RIGLLVPQSGpykAIGDDLVKGWQLYLDthdgklgGHRVQVVTADEaegkQSALNAARKLLDkdKVAVIAGTGSAdaVES 120 Micromonospora peu...
OLE25232   50 RIGMIVPQAGgnkPIGDDLIAGFQLYLNlhgsrlgGHPIQLIMAEEgdsaETGRAAVDKLIKehAVQVMSGVAGStvMTA 129 Actinobacteria bac...
OIV37447   35 TVGFLASQTGiyqPVGEDMINGFRLYLAlhgnrlgGHRVHLVVGDEglgpDKAVPATTTMVKkdRISLLAGGVGGgtVTA 114 Streptomyces sp. M...
SDK68791   38 SIGLVVPTSGvhkSIGTDMARGFDLYLDqhggklgGRLIDVVEADEgdrtEIGVAAVTRLIQddEVQAVVGVVSSetALA 117 Nocardioides sp. Y...
ACU74045   63 PVGLLLDLSGangSAGADARDGFQLYVRqhggrlgGRPAQLTISNEgptpAATATTMQDLLAh-GVQAVVGPIDYagYES 141 Catenulispora acid...
SEG98401   31 KVGAIISQMGvyaMLGDDMEAAMRLYLDdhggrlgGRPAELLVADDagspERGQKEARRFIDdeGVDVITGLIAS--PVA 108 Nonomuraea solani
EGP08590   20 KIGLMLPYKGvyaLPAESIDRGFQLALEefgnksnGRPIEVIRADDeltpSVGVQKFNKLVQgdKVDIVAGIIGSnvGIA 99  Bradyrhizobiaceae ...
KQW61776   30 KIGLVLPYRGvwaQLSEPMERGFQLAIDeyg-palGRPIEIIRADDeltpSVAVQRFNKLVSsdQVDLIAGVIGSnvAIA 108 Variovorax sp. Roo...

Feature 1                    ###                 #                            # #   #         
4EVQ_A     98 XVKIAREDGIPTIVPNAGADiitraxcapnVFRTSFANGQIGRATGDAXIkag-lkKAVTVTWKYaAGEEXVSGFKKSFT 176 Rhodopseudomonas p...
ADD43787  117 VAPEATKAEVPLLGYGGQPPlddagidfkwLWQTSFSTSQLGASIAPYIKdkv-dgSVYTIAPDYeGGKAVMGSFIKPFM 195 Stackebrandtia nas...
SCL73590  121 IKTLVTERKTPFVGTGGRPStltd---vsyIWHTSWLSRETGQAIAEHVRttv-dgPVYVIGPDYqGGYDQIGGFVDTFV 196 Micromonospora peu...
OLE25232  130 IRDQVEAAQVPLLGSNASPNtlgs---vkyIWRTSYVNDEAGRALGGYLAtrr-nqSVYVVSDDSePAREQVSGFLRTFN 205 Actinobacteria bac...
OIV37447  115 VQDLTRQAQIPFLAANAGPDkpk----leyLWQTSYLSTDPGTALAPQVLkdv-rgPVYAVGPDYqGGWDELRGFTAEFA 189 Streptomyces sp. M...
SDK68791  118 AKDVAKNSETPLIVTGAGADgfad--gsdyLWRTSSTNAGLGSALGKAVAqgtdrgSAYVIGSDDaAGHEFSDSFMISLE 195 Nocardioides sp. Y...
ACU74045  142 AAPLADAAHVPLVGVVARPDvtd----isyVWNVAFLSTEPGAALAPFIYnhv-ksPVYAIGGNYpGDWEQVRGFTDAYY 216 Catenulispora acid...
SEG98401  109 VSVVKESGRTPVVIANAGADelg----ganVFRVSYTNHAHGHAAGRYAAeryggqRVVLMASDYsAGTETLQGFVDGYG 184 Nonomuraea solani
EGP08590  100 ISELAEKNKVPLVFANAFADeitgkfcspyIARTSFSANGFEYASGKYWAskg-ikTAVTMGPDYtAGRAFIDGFKRGFE 178 Bradyrhizobiaceae ...
KQW61776  109 LSELADRAKKPIVFSGSFADevtgkycspyVARTSFSANGFQFNAGKYWAskg-ikTAFILGPDYaAGHAWLGAFRRGFQ 187 Variovorax sp. Roo...

Feature 1                                                      #                              
4EVQ_A    177 ag--kGEVVKDITIafp-----------dveFQSALAEIASLkpdCVYAFfsggGALKFIKDYAAAnl--gIPLWGPGfl 241 Rhodopseudomonas p...
ADD43787  196 ea--gGKLANAEKEpawtpw------pktmdFSKYFEEAAASdakAIFAYyggaPAIEFVKQYAKSpa-kdIPLYGAFlt 266 Stackebrandtia nas...
SCL73590  197 ka--gGKLANDDGKpawtpw------pgttnFLPYLNKITSSgakAVYCFyagtMAVDFVKQYEQAglkgkVPLYGAGfl 268 Micromonospora peu...
OLE25232  206 glpghPDVVGDPVQiplvs-------spnlpLGSYLNAIHASgarTVFAAfsadTAIPFFKAWRAAgm--sTPIYAPGfv 276 Actinobacteria bac...
OIV37447  190 ki--gGKLANPGGKtlfid-------mkvtdFTPYFARIQASgakAVYAFfaggAAIAFVKQYRQSpl-ahLPLYGPGfl 259 Streptomyces sp. M...
SDK68791  196 as--gSNVAGQSYTpagv----------teeWSGLFEKVEESgadAIFAAyagkEAEAFVKQYRESglarsTRLYGPGfl 263 Nocardioides sp. Y...
ACU74045  217 al--gGRLANPENLptftpaasfgpanattdFAPYLQAIKASgakAVYCAftgdEAVRFVQQYARSvv-knIPLYAVGlv 293 Catenulispora acid...
SEG98401  185 ae-plKRILTPYGRvt--------------dLEPYFERIPPEa-gLLFAFyaggEAITFARAFKRLgydtkVKLLTCMnl 248 Nonomuraea solani
EGP08590  179 en--gGKVVEQIWTpfqk----------tkdYSAALTQAANAnaeIIYAFyagaEAIQVVKQHADFglrskVPLIGDHwv 246 Bradyrhizobiaceae ...
KQW61776  188 aa--gGKVVQEAWTpfqk----------tkdWGPALTQASTSgaqMIYSIyagnEAAQVVKQHAEFglrekLPLIGDQwv 255 Variovorax sp. Roo...

Feature 1                                                       #                             
4EVQ_A    242 tdg--veaaaGPAGDGIKTVLHYvsdldnAENQAFVKSFEAAykip-pdvFAVQGWDAGQLLDAGVKavggd---vakrK 315 Rhodopseudomonas p...
ADD43787  267 ega--vleaqGEAAEGVQTVMNYapdidnAANRRFVSEWSEInsdrptslYSMVGWDAALVLDQAISriplde-evtpaK 343 Stackebrandtia nas...
SCL73590  269 tegs-vlaaqGAAADGVQTVLNYaanldnAANRAFAPAYQQKhqta-pnlYNVTGYDAALVLAAAIAaagdk---ptseS 343 Micromonospora peu...
OLE25232  277 tegptalrdlGDSVSGLYTAMNYapdldnGANRTFASAFQQLynml-pstYAMASYDAAAVLDKALAlagsd---lspqS 352 Actinobacteria bac...
OIV37447  260 tegtptlnaeGSAALGVTTSLNYsadldtAANRAFVAAWSARhpgtlpttYAMASYDAAAVADRAIAaatkdgnvptpqQ 339 Streptomyces sp. M...
SDK68791  264 tegd-vlsalGGAASGVRTALHYsdtmdsLMNDAFVKDYRKAydat-ptvYSVQAYDAAAALDKALGlsdd----vdrnE 337 Nocardioides sp. Y...
ACU74045  294 tdgp-llqqeGAAATNITSVLDYspdvdtAANRAFVSAWAAGhdgrepsvYSLTGYDAAALLDQAVAqagpk---adaaS 369 Catenulispora acid...
SEG98401  249 tded-vllatRADVEGITSVGMYspalvnPDNTAFVARWQALtgrd-psaMAVQGWDAMRLIDEAVArg---------gD 317 Nonomuraea solani
EGP08590  247 ydea-lwpalGDLVINARHVATHypgvptEVNRKFVKAYQDKfkie-pdvSAELGYDNGKAIMLTLEklggk--ipedrA 322 Bradyrhizobiaceae ...
KQW61776  256 ydeg-lwpalGDLVYGAKFIASYfpelenSENKKFVAAYQKKygkv-peiNAALGYDNGKAIMLALGktagv--mpadgA 331 Variovorax sp. Roo...

Feature 1                                                   
4EVQ_A    316 ELNAAXaaasfasPRGPFKLSAa-HNPVQ--NFYLRELkggKSVNL 358 Rhodopseudomonas palustris CGA009
ADD43787  344 INKAMGelgtinsSRGSWQFDEelHIPIQ--RWYLRTVakdGPSLT 387 Stackebrandtia nassauensis DSM 44728
SCL73590  344 INAAIGklgaidsPRGQWRFGAs-HSPIQ--PWYLRKVqndGRARA 386 Micromonospora peucetia
OLE25232  353 INTALSelgeidsPRGSWQFNQt-RTPLQ--RWYLRQVrreGVVLT 395 Actinobacteria bacterium 13_1_20CM_3_71_11
OIV37447  340 INTAIGglgqlpsPRGTWQFNKttHAPAQ--PWYLRTVvkdGNSLA 383 Streptomyces sp. MUSC26T
SDK68791  338 IADSLGsvgtivsPRGNWSFDPn-HNPDQ--PYFLRVVrgtADGPR 380 Nocardioides sp. YR527
ACU74045  370 INAAIGalgridsPRGAWQLASstHAPIQ--KWYLRRVqvdGTALA 413 Catenulispora acidiphila DSM 44928
SEG98401  318 LTRALGevgelggPRGRFRLDAr-HNPVQ--NWYAREYhngVNRVI 360 Nonomuraea solani
EGP08590  323 KFISTMrgltfdaPRGKIRFNA--QNSAQleKVYLVEIvkgADGKP 366 Bradyrhizobiaceae bacterium SG-6C
KQW61776  332 QFISNLrsldfdsPRGKIRFNK--HNSAQleKVYVLELvkqSNGQP 375 Variovorax sp. Root411

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