Conserved Protein Domain Family
DEXDc_SHPRH-like

?
cd18008: DEXDc_SHPRH-like 
DEXH-box helicase domain of SHPRH-like proteins
The SHPRH-like subgroup belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Statistics
?
PSSM-Id: 350766
Aligned: 63 rows
Threshold Bit Score: 151.286
Created: 3-Feb-2014
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
 
ATP bindingDEAD box
Feature 1:ATP binding site [chemical binding site]
Evidence:
  • Comment:based on the structure of Saccharomyces cerevisiae Chd1 with bound gamma-thio-ATP

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                            #######      
XP_003219235  636 LLLHQKQALAWLLwre---------------------------------------nqkPCGGILADDMGLGKTLTMIALI 676  green anole
EEA28537      252 LFHHQVLGAGFMRerek-------------------------------------skdqPKGGMLCDVMGLGKTIQTLANI 294  Penicillium m...
CBX93817      437 LKHYQILGTAFMRrret-------------------------------------saeePRGGLLADQMGLGKTLMMLANI 479  blackleg of r...
Q9M1I1        330 LFPHQQAAVGWMLererkaevsshplylsfdtedg-fsfyvnavtgdiiteaapmvkdFRGGMFCDEPGLGKTITALSLI 408  thale cress
ABO96387      101 LHPHQRAALGWMRrrerarlppildplwkpidcedgrvlwlhtlkgelsdhhpdvyedSQGGMLCDEPGLGKTVTALALV 180  Ostreococcus ...
CCA36786      254 LYKYQRRSIVRMLekelypssslspnlvvvpdlyk-tnsfylhvteltfqrdkstlslPRSGILAENMGLGKTCLCLVLI 332  Pichia pastor...
EEQ37877       32 LYPYQINSLCKMYekettsqrepvpnflsfrspln--styyfdtlnpafysnpelyvkPRGGILAENMGLGKTLICLSLV 109  Clavispora lu...
EFZ00316      208 LYAYQRRSIAVMVqkeaepskvldprliaidghdg--tpwytdpvagtilrepryydgVCGGILAEEMGAGKTIICLALI 285  Metarhizium a...
EGE79308      261 LYAYQRRSAAYMIqresepaqmldprlqalhgptg--qpyyydkeegnilhekrlyseACGGILAETMGYGKTLICLAVI 338  Ajellomyces d...
CAZ84401      160 LYGYQKKTVAMMIqrelapentqdarfrcftgpqg--rkyyldlettemlveprkyedVRGGILAEDTGTGKTFICLALI 237  Tuber melanos...
Feature 1                                                                                         
XP_003219235  677 LAQKlkqrekgktkekkle------------------------------------------------------------- 695  green anole
EEA28537      295 VDGAdekle----------------------------------------------------------------------- 303  Penicillium m...
CBX93817      480 VNGQpprgs----------------------------------------------------------------------- 488  blackleg of r...
Q9M1I1        409 LKTQgtmadppeglpivwcthksdkkcayyeytsdqftsnsmsavkrfqspsscrnqvsfeafrplleskslpfkqarlm 488  thale cress
ABO96387      181 LARRgwrpsppigytarkmescwyyedtnsggaggygspavmaavptldaetpaitpmktsaafagsssrgnssglrrsk 260  Ostreococcus ...
CCA36786      333 YITKyqlptipkefryqsqqtekvislqelcvnmlsqeslswkqfrselp------------------------------ 382  Pichia pastor...
EEQ37877      110 CLTKydvsiipedmilhddqapssnkipslcdvsidtinrnslpwkfyeedi---------------------------- 161  Clavispora lu...
EFZ00316      286 LATRnlptrppelcsgiscpkrnkiasladmaaacatrhavpwrsyfetwrr---------------------------- 337  Metarhizium a...
EGE79308      339 LATRghfpripihcmeglhpvrektasllemaaatagrfslpwksyferlea---------------------------- 390  Ajellomyces d...
CAZ84401      238 LATKyqysfipeeheepsllrqsppslsdlavaaiwkhslgwgefkdd-------------------------------- 285  Tuber melanos...
Feature 1                                                                                         
XP_003219235      --------------------------------------------------------------------------------      green anole
EEA28537          --------------------------------------------------------------------------------      Penicillium m...
CBX93817          --------------------------------------------------------------------------------      blackleg of r...
Q9M1I1        489 dpddqtlesknsnfenefethipasldlkaqcrkslgnvrknllpayngaselsevmeakrisnwkkcgmitgckrkglt 568  thale cress
ABO96387      261 rsagntpvgyfasvckngldgtmsrsakrskleekqayealaaattvevpdwqtrlecsahs------------------ 322  Ostreococcus ...
CCA36786          --------------------------------------------------------------------------------      Pichia pastor...
EEQ37877          --------------------------------------------------------------------------------      Clavispora lu...
EFZ00316          --------------------------------------------------------------------------------      Metarhizium a...
EGE79308          --------------------------------------------------------------------------------      Ajellomyces d...
CAZ84401          --------------------------------------------------------------------------------      Tuber melanos...
Feature 1                                                                                         
XP_003219235      --------------------------------------------------------------------------------      green anole
EEA28537          --------------------------------------------------------------------------------      Penicillium m...
CBX93817          --------------------------------------------------------------------------------      blackleg of r...
Q9M1I1        569 dsdvesdiwmqcdscskwrriidegvsvtgsawfcsnnndpayqscndpeelwdksqpikylqgfytkgasgeesdnisf 648  thale cress
ABO96387      323 --------------------------------------------------apigfiartglkedsarlarntsyfesilr 352  Ostreococcus ...
CCA36786          --------------------------------------------------------------------------------      Pichia pastor...
EEQ37877          --------------------------------------------------------------------------------      Clavispora lu...
EFZ00316          --------------------------------------------------------------------------------      Metarhizium a...
EGE79308          --------------------------------------------------------------------------------      Ajellomyces d...
CAZ84401          --------------------------------------------------------------------------------      Tuber melanos...
Feature 1                                                                                         
XP_003219235      --------------------------------------------------------------------------------      green anole
EEA28537          --------------------------------------------------------------------------------      Penicillium m...
CBX93817          --------------------------------------------------------------------------------      blackleg of r...
Q9M1I1        649 ftsvlrehkssvsstvkkaliwlaklpleklsqmetvglpgpvlglkldalgfqrifrafglksrvekgvtkwfypkfle 728  thale cress
ABO96387      353 ncvvyvgraatcdvvdyilenteevshamplsmplfrrnsdqppifralglepytgvgklenaipyappgsatedlildk 432  Ostreococcus ...
CCA36786      383 -------------------------------------------------------------ascikalrshppsfqytts 401  Pichia pastor...
EEQ37877      162 ------------------------------------------------------------pssvveklkhnpgsfkisin 181  Clavispora lu...
EFZ00316      338 -----------------------------------------------------------qigyefhrceaalkrnpgyyl 358  Metarhizium a...
EGE79308      391 ------------------------------------------------------------sgmhfekcisacesnrgsya 410  Ajellomyces d...
CAZ84401      286 ----------------------------------------------------------------lgavnlaklraahafy 301  Tuber melanos...
Feature 1                                                   #                                     
XP_003219235  696 ------------mwmsrkdstvvnscsTLIVCPASLIHHWKNEIERhvrs----gnlKVCLYHGPnriknt--------- 750  green anole
EEA28537      304 ----------------------dnantTLIVAPRGLITQWKMQIEKhvqnn--vlvpILCHYAGSrnnssdi-------- 351  Penicillium m...
CBX93817      489 ----------------------selktTLLVASPALLSQWKSEFEQhte------rnLTILRYGAgyridstn------- 533  blackleg of r...
Q9M1I1        729 nlvfdvpalkvalcqpldtfrlylskaTLIVVPTNLVNHWLTQIQKhvc------sdQLRILVWAdhielsp-------- 794  thale cress
ABO96387      433 qalhdairvvdnrgsssepmrvwlssaTLIIIPSVLIEHWLQQISFctwnitgegvpRVAVLDKPpkvdgfssvyktegs 512  Ostreococcus ...
CCA36786      402 snetrksarlkvkdtitiskqlylsaaTLVIVPDNLYRQWITEIDKhf-------spNAFELLGFpqgsdpefp------ 468  Pichia pastor...
EEQ37877      182 hgksqwsertkskkiqptskslylcgtTLLIVPENLFHQWNSELKKhid-----dnyLHKLFVSDrfkkpivlpnsiyt- 255  Clavispora lu...
EFZ00316      359 rpppklrrtgrhpvqelaptkiylsnaTIVVVPTNLLSQWKHEIAKhtt------slTVRVLSKDesipsl--------- 423  Metarhizium a...
EGE79308      411 ilrppqryksrevalkvtptklrlcsgTLIVVPPNLVDHWLSEIDKhtq------glKVLVLRDSrratppp-------- 476  Ajellomyces d...
CAZ84401      302 evqppsrsrskryspsdvkeriylgtgTIVVCPPNLVDQWKREINIhvee---kalkTLALVKSSegippv--------- 369  Tuber melanos...
Feature 1                                                                                    ##   
XP_003219235  751 ---------------tvlseyDVVVTTYSILAKeiptqkeeveaaaedf----vvqdkslpfsplpwihWARIILDEAHN 811  green anole
EEA28537      352 ---------------elflqsKIILTSYDEIRIsypkmkekpenlspeellrwgvrnfmnsagplhqfrFRRIILDEGQQ 416  Penicillium m...
CBX93817      534 -------------pdeilsghDIILTSYTEVMRsypkndppiecqtaeqkiawwkevyetqrgvlhrmrFLRVVLDEAQA 600  blackleg of r...
Q9M1I1        795 --------------hslawdyDVVITTFSRLSAewnprkk----------------------spliqvhWLRVMLDEGHT 838  thale cress
ABO96387      513 lepvhlndlahvdakdlandfDIVIMPINRLSTefskvdt-----------------------pilrilWQRVILDEGHQ 569  Ostreococcus ...
CCA36786      469 -------------pleklldvDIILIASSIFARendssds-----------------------vlrciyWKRLIVDEGHS 512  Pichia pastor...
EEQ37877      256 --------dclpqdpkeliqyDLVVITSAAFAKqdldrt------------------------alahvyWKRLIIDEGHS 303  Clavispora lu...
EFZ00316      424 ---------------relldiDIILFSQSRFERlvkesggvg-------------------gtalsvvhFKRCIVDEGHK 469  Metarhizium a...
EGE79308      477 ---------------eklleyDILLFSKSRFEKeaggggrssgfap-----------eprkdsplkrlhWLRIIVDEGHN 530  Ajellomyces d...
CAZ84401      370 ---------------sdlleyDLVIIARPRFDMeeregrdkagrh-------------avyksplmsirWKRLIVDEGHS 421  Tuber melanos...
Feature 1                                                                                         
XP_003219235  812 IKNp----kVQASMAACKLRaTARWAVTGTPIQNn----LLDMYSLLRFLRCspfdefkvwrnqvdn------------- 870  green anole
EEA28537      417 IRNp----eSQTSIAVRALHgHYKWILTGTPLLNh----SAEFWAYFKFLGVpnigrfssfvtnfcn------------- 475  Penicillium m...
CBX93817      601 IKNh----mGRTSIACRALMaTHKWALSGTPILNs----LTELYPYFKFLGVphtgsfkifkhnycd------------- 659  blackleg of r...
Q9M1I1        839 LGSsv--slTNKFQMAVSLTaCNRWLLTGTPTPNtpnsqLSHIQPLLKFLHEevygenpkfweagilrpfeaemeegrlr 916  thale cress
ABO96387      570 LGAsl--avTAKLSVACALKaHARWLMTGTPTPTt----LKGAGTAHLQPLLgflrqppygtsaglwttav--------- 634  Ostreococcus ...
CCA36786      513 MSSk----iSRPSELARSLYvERKWVISGTPTRGl----TRLHVNKEEVQKPfnakddllklgflitkflnvplwsndpk 584  Pichia pastor...
EEQ37877      304 MGSk----sSNISVLCSALQtERRWVVTGTPTPGl----TNLHMDEDESGHNthtkktrkyvvkkafnvkedlvklgnlv 375  Clavispora lu...
EFZ00316      470 LGNskicrkSNLLRGLDRMNfSSRWIVTGTPSHGl----FGVDNRTPAGSSPrdptllpiqtretsaemekkdlerlgsi 545  Metarhizium a...
EGE79308      531 FAAkg--arTTAVHALSQLHvERRWVVSGTPSRGl----YGIEVALASQESVeggcekqgdassilq------------- 591  Ajellomyces d...
CAZ84401      422 MASsss-lmNRGVCVAQRLPvERRWIVSATPVTGl----LGMSSGMNIGETEealearreqeleerrva----------- 485  Tuber melanos...
Feature 1                                                                                         
XP_003219235      --------------------------------------------------------------------------------      green anole
EEA28537          --------------------------------------------------------------------------------      Penicillium m...
CBX93817          --------------------------------------------------------------------------------      blackleg of r...
Q9M1I1        917 llqllqrc-------------------------------------------------------------missrkkdlqm 935  thale cress
ABO96387          --------------------------------------------------------------------------------      Ostreococcus ...
CCA36786      585 awnqqvvrpfiskcfnselqlfqilnslmvr--------------hsvtevedqvdlpplvhdvvliepgyynrisvnlf 650  Pichia pastor...
EEQ37877      376 gnyfkiepfcsqprlwssaivknlassgfssemslrtllsslmvrhslanvesdlslpqlhheavllapsnqnklainlf 455  Clavispora lu...
EFZ00316      546 sslylkarpwa-------------------------------------------------------nvatenedtradwg 570  Metarhizium a...
EGE79308          --------------------------------------------------------------------------------      Ajellomyces d...
CAZ84401          --------------------------------------------------------------------------------      Tuber melanos...
Feature 1                                       
XP_003219235  871 ----------ntrkggerlailtrSLLLRR 890  green anole
EEA28537      476 ----------gsdlsnqrlvnivqKVVYRR 495  Penicillium marneffei ATCC 18224
CBX93817      660 ---------nkdpenterllvrlsQFMMRR 680  blackleg of rapeseed fungus
Q9M1I1        936 ippcikkvtylnflpgharsynelVETVRR 965  thale cress
ABO96387      635 -----qrplegrdrfaqadavvrlGDVLRR 659  Ostreococcus lucimarinus CCE9901
CCA36786      651 tsllatnavtsertdrdymfhpsnGAELRR 680  Pichia pastoris GS115
EEQ37877      456 navlavnavsseregsdymfdpanRSQLRR 485  Clavispora lusitaniae ATCC 42720
EFZ00316      571 tylllprhkknsygrrdrlkatlnSLIIRH 600  Metarhizium anisopliae ARSEF 23
EGE79308      592 ---------arkmstnvmeeelknIDKLRS 612  Ajellomyces dermatitidis ATCC 18188
CAZ84401      486 --------qtnesndleklgrivcDFLRVR 507  Tuber melanosporum Mel28

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap