3ULT


Conserved Protein Domain Family
LbR_Ice_bind
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cd12796: LbR_Ice_bind 
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Ice-binding protein, left-handed beta-roll
The ice-binding protein of the grass Lolium perenne (LpIBP) discourages the recrystallization of ice. Ice-binding proteins produced by organisms to prevent the growing of ice are termed to anti-freeze proteins. LpIBP consists of an unusual left-handed beta roll. Ice-binding is mediated by a flat beta-sheet on one side of the helix.
Links
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Statistics
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PSSM-Id: 240609
Aligned: 9 rows
Threshold Bit Score: 87.0689
Created: 1-Feb-2013
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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Conserved site includes 68 residues -Click on image for an interactive view with Cn3D
Feature 1:putative water-binding motif
Evidence:
  • Comment:X[NH]XVX motif creates troughs, where water binds to the exposed "X" residues (typically with polar side chains)
  • Structure:3ULT: Lolium perenne Ice-binding protein bound to ethanol; contacts at 4A
  • Comment:Ethanol contacts simulate water contacts to XNXVX motif
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1               #####             #####   #####  #####     #####  #####   #####   #####  
3ULT_A         5 PNTISGsNNTVRSGs---KNVLAGNDNTVISGdNNSVSGsNNTVVSGN--DNTVTG-SNHVVSGTNHIVTd-NNNNVSGN 77   Lolium perenne
ACN38297     180 NNSVRSgKNNVVSGn--nNIVISGNSNVVTGNhNTLLRGsDDNAVSGS--KHVVSG-THHVVTGDNNAVTr-NHNTVSGS 253  Antarctic hair...
BAJ91032     298 NMPLYVkRNRRALQqq-qPNVISGGNNTVRSGgGNVLSGdNNTVISGN--NNTLSGtNNTVVSGSNNVLTg-SNHVVSGS 373  domesticated b...
ACN38303     166 QIALSGqPNTITGT----NNYVRSGVNNVVSGnHNTVTSgNNNVVSGN--HNTVSG-TNHVVTGNNHVVTr-NQNTVSGS 237  perennial ryeg...
AAX81543     293 HSPGMAfTNMPLYEk--rNRRILGQQPNVISGsRNTIRSgTNNVLSGNd-NTVISG-NDNVVTGSNNVVSg-SGNVVTER 367  bread wheat
XP_003580880  98 LESLNLaHNRLQVGtt-fPSWIAEFDRLCYLDlSHNVSP-LHVKSSSR--RTLATG-QPNTITGANNSVRsgSGNTIMGD 172  Brachypodium d...
AAX81542     125 DNSLVGeVPKSLIRl--kGLVIAGHSLGMVFTnMPLYVKrNRRTLDEQ--PNTISGsNNTVRSGSTNVVSg-NDNTVISG 199  bread wheat
EJK45133     214 SNGLGSsKCSLSSSsadeYNGDDNDATVKCSGtGNIIVGhQHDDLSAG--HKAITG-SHNIILGEGHTVTs-HGGIVSGV 289  Thalassiosira ...
ACE75207     136 ANGLSSfLNGVPGPs--hQESQKLGQNLNELGsNHQVPSkNHQSLSANhhNHRVPG-QNHQVPGQNHQVPg-QNHQVPGQ 211  Glyptapanteles...

Feature 1          ####  #####   #####   #####    ####   ##### 
3ULT_A        78 d-NNVSGSFHTVSGG-HNTVSG-SNNTVSGs--NHVVSG-SNKVVT 117  Lolium perenne
ACN38297     254 h-NTVPGSHNTVSGS-HNTVSG-SHNTVSGs--NHIVSG-NNKVVT 293  Antarctic hairgrass
BAJ91032     374 n-NVVSDTSHVVNGS-NNTVSG-NNNTVSGs--NHVVSG-NNKVVT 413  domesticated barley
ACN38303     238 h-HKVSGGHNTVSGS-HNTVSG-SHNTVSGs--NHIVHG-NNKVVT 277  perennial ryegrass
AAX81543     368 n-HVVSGSDNVVSGR-NNVVTG-SNNVVSGr--NHVVSG-NNKVVT 407  bread wheat
XP_003580880 173 g-NTITGDNNVVSGN-NNTVTG-SNNTVSGs--NHIVNG-DNLVVT 212  Brachypodium distachyon
AAX81542     200 nnNNVAGSNNTVITGnDNTVTG-SNHVVSGd--KHIVTD-NNNAVS 241  bread wheat
EJK45133     290 g-HVASGDHASAIAGsGNTVSG-TGAIALGg--NHGTARgSNSVVS 331  Thalassiosira oceanica
ACE75207     212 n-HQVPGQNHQVPGQ-NNQVPGqNNQTSSAnhkNHQVPS-QNHQIL 254  Glyptapanteles flavicoxis

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