Conserved Protein Domain Family
RRM2_Nop4p
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cd12675: RRM2_Nop4p 
RNA recognition motif 2 (RRM2) found in yeast nucleolar protein 4 (Nop4p) and similar proteins
This subgroup corresponds to the RRM2 of Nop4p (also known as Nop77p), encoded by YPL043W from Saccharomyces cerevisiae. It is an essential nucleolar protein involved in processing and maturation of 27S pre-rRNA and biogenesis of 60S ribosomal subunits. Nop4p has four RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains).
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Statistics
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PSSM-Id: 410076
Aligned: 5 rows
Threshold Bit Score: 152.249
Created: 7-Feb-2012
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
585573        147 PKLIIRNMPWScRDPVKLKKIFGr-YGTVVEATIPRKrdg--klCGFAFVTMKKISNCRIALENtkDLKIDGRKVAVDFA 223  baker's yeast
O74400        107 PRLIIRNLPWSiKKPQHLEPHFSk-FGKVREIKIPTKggg--rmCGFAFVWMKDRKAAEEAMNSlnGTEIDGRPIAVDWA 183  Schizosacchar...
EAA33697      156 NKLIIRNLPWSiKKPEQLAELFKp-YGKVRFADLPNDkg---klSGFGFVTLRGRKNAEKAIEAvnGMEVDGRPLAVDWA 231  Neurospora cr...
XP_023897287  148 CRLIVRNLPWTiKNESQLTKLFLs-FGKVKQAYIPRKggagglsSGFGFVVMRGRKNAEKALESvnGKEVDGRTLAVDWA 226  Quercus suber
CCJ28986      713 PFLIIRNLPWSvRKKDHAFFLEFgkYGKVVNVIIPRKkgg--kmSGFAFVHMKQMSAAEEAIKCinGVELEGRHVAVDWA 790  Pneumocystis ...

585573        224 VQKNRW 229  baker's yeast
O74400        184 VSKDAF 189  Schizosaccharomyces pombe 972h-
EAA33697      232 VDKQTW 237  Neurospora crassa OR74A
XP_023897287  227 VDKETY 232  Quercus suber
CCJ28986      791 LSQSEW 796  Pneumocystis jirovecii
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