Conserved Protein Domain Family
RRM1_MEI2_like

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cd12524: RRM1_MEI2_like 
RNA recognition motif 1 (RRM1) found in plant Mei2-like proteins
This subgroup corresponds to the RRM1 of Mei2-like proteins that represent an ancient eukaryotic RNA-binding proteins family. Their corresponding Mei2-like genes appear to have arisen early in eukaryote evolution, been lost from some lineages such as Saccharomyces cerevisiae and metazoans, and diversified in the plant lineage. The plant Mei2-like genes may function in cell fate specification during development, rather than as stimulators of meiosis. Members in this family contain three RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains). The C-terminal RRM (RRM3) is unique to Mei2-like proteins and it is highly conserved between plants and fungi. Up to date, the intracellular localization, RNA target(s), cellular interactions and phosphorylation states of Mei2-like proteins in plants remain unclear.
Statistics
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PSSM-Id: 409944
Aligned: 16 rows
Threshold Bit Score: 108.905
Created: 20-Dec-2011
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9SJG8        197 SRTLFVRNINssVEDSELSALFEPFGEIRSLYTACKsRGFVMISYYDIRAAHAAMRALQnt--lLRKRTLDIHFSIPKE 273  thale cress
EFN52088      373 SRTLFVRNVDpsVPEDELRTLFEAFGEVRSLYTAAKaRGFVVVSYYDTRAATLAKHTLTgq--mLAGQQLDVHFSLPKD 449  Chlorella vari...
XP_002670292  419 SRTLFVRNISsvVDDQELRILFESFGPIRQMYTSCKhRGFVMITYYDIRHAKQAKKNLQsk--lIKKRKIDIHYSIPKE 495  Naegleria grub...
Q9LYN7        210 SRILFVRNVDssIEDCELGVLFKQFGDVRALHTAGKnRGFIMVSYYDIRAAQKAARALHgr--lLRGRKLDIRYSIPKE 286  thale cress
XP_002980347  202 SRTIFVRNIDskVSDDELRAVFERFGDIRTLYTGCKpEGLILVSYYDLRGAKRAIRALQsr--vLWGQKLEMHFLFPKD 278  Selaginella mo...
Q75M35        269 SRTLVVRNITanIEDSDLTVLFQQYGDIRMLYTSFKhHGFVTVSYYDIRAAQNAMRALHsk--pLGLMKLDVQFSFPKE 345  Japanese rice
EAL50153       36 SRVLCVFNILsqYDPKELLCIFQQYGDVKTIYYSTVqFGFIVVIFYDIRSSRSAAKYLNghineGPNHGTLVIFNIDKQ 114  Entamoeba hist...
EAL47493       23 THTLFISNINseVSSEAYYQLLESFGEIEAINFETKsRGFIIVTYYDIRSAKIAIKILQkt--vIGNQTLEVHYTISRD 99   Entamoeba hist...
GAA98917      231 GRTLFVRSVKydTKPQDIRDMFERFGEIRSFYDIIGkRGMAFVSYYDLRAAQMAKERLQgt--qLQGRPIDVHFGVPRD 307  Mixia osmundae...
EAL46274       25 SRILFVRNICfnTNEESIKKLFEKYGEIKKVFCQIEnRGIAFITFYDIRDAIKAHEELNkk--eIGGRPIKIHYSLPKD 101  Entamoeba hist...
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