Conserved Protein Domain Family
CE4_yadE_5s

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cd10966: CE4_yadE_5s 
Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins
This family contains an uncharacterized protein yadE from Escherichia coli and its bacterial homologs. Although its molecular function remains unknown, yadE shows high sequence similarity with the catalytic NodB homology domain of outer membrane lipoprotein PgaB and the surface-attached protein intercellular adhesion protein IcaB. Both PgaB and IcaB are essential in bacterial biofilm formation.
Statistics
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PSSM-Id: 213024
Aligned: 23 rows
Threshold Bit Score: 177.855
Created: 13-Jun-2011
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative activeputative metal
Feature 1:putative active site [active site]
Evidence:
  • Comment:based on similarity to other CE4 superfamily members

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                ##                                                                 #   
P31666      230 PARAVVITFDDGLkSVSRYAYPVLKQYGMKATAFIVTsrikrhpqkwnpkslqfMSVSELNEIRD-----VFDFQSHTHF 304 Escherichia coli...
EGQ27022    213 PEKSVLITFDDGYsSTADLAYPILKSHRFKATAFLIAsrie---------rpgyLTEEQIRSTQD-----MISYQNHTYD 278 Sporosarcina new...
YP_076179    55 PDRPVMVTFDDGYrSNYLHAYPVLQQHGFSGVIFMVTglagqk-----vgrleyLTWEDMHAMTAs---gVIEIQAHSHD 126 Symbiobacterium ...
ZP_07833041 234 PKNSVSITIDDGTaSIYKYAYPLLKKYGDSATLFLIGnhl-----------kddKLPQSFQEMKQn----GMELQSHSYG 298 Clostridium sp. ...
ZP_06160872 232 PAKSVVLTFDDGQyGFLDYGIPLLEKYKVPATAFLIGdn--------------dNTEEIIHEKASp----YIDFQNHSYA 293 Slackia exigua A...
ZP_02861896 255 PKKSIVITFDDAAqSFLDNGVPILNELKIPATSFIITs---------------hNGKKKVKDYKSk----YITFQSHSHD 315 Anaerofustis ste...
ZP_03634566 256 PEKSVAITIDDGDpTVYQYAYPVLKDFGYNATLFLITgwm------------npQLPYEFFQMREd----GLELQSHSFL 319 Holdemania filif...
ZP_03167620 190 PDKSIVLSFDDGP-LYIELAIPLFEKYQTPATSFVITsy--------------yNDKSMLDPYRNn---qYLTLESHTDN 251 Ruminococcus lac...
ZP_07670977  94 DAKSVVITFDDGFySTTKFAQPVLKRYGFTGSVFVIGsaideh------hgpykPSIRQHASHADmkderVLQYYSHSYN 167 Erysipelotrichac...
ZP_07831991  94 DEKSIAITFDDGFySTTKFAQPVLKRYGFTGSVFVIGsvideq------hgpydPKLRQHASHADmqderVLQYFSHSYD 167 Clostridium sp. ...
Feature 1        #                                               ###                            
P31666      305 LHRvdgyrrpi---llsrsehNILFDFARSRRALAqfn---phVWYLSYPFGGFNDNAVKAANDAGFHLAVTTMKGKVkp 378 Escherichia coli...
EGQ27022    279 LHGfnsmtgla--lleytprsAIYTDLTMANQKIGsilpeqppVSALAYPYGLRNTEAIRASKVAGMKSAYTITEGNVfq 356 Sporosarcina new...
YP_076179   127 GHRnidgqpa----lvhwseeEILADWQLLSEALAaae--lppATAYAYPFGAHDQECIDALRKAGVKLGFTVHHGHVtq 200 Symbiobacterium ...
ZP_07833041 299 MHTggcegghgg-alrcvahdEGVTDTEKSFSIIGg-------GNVYCYPYGDVTDSALQIMKDAGVHMAFTTNYGKIep 370 Clostridium sp. ...
ZP_06160872 294 MHTggstaighggriydltaeQITADLQKLSDMLGt-------NEAFAYPYGDVSDAAPGAVKDAGLLCAFTTAYDQVhv 366 Slackia exigua A...
ZP_02861896 316 MHRsggtvghgg-vmtalteeDIIKDLKTSFKICGh-------SEAFAYPFGDYSESCEIALRNAGVLCALTTNYGKVyp 387 Anaerofustis ste...
ZP_03634566 320 MHQggckaghgg-rilcvdhdEGVADTRQSLEYVDg-------GFVYCYPFGDVNDHAVEILQEAGVQLAFTTEYGKIkp 391 Holdemania filif...
ZP_03167620 252 MHRgggtyghgg-ifpalskeEALADLKKSIEYCGn-------GDALAYPFGDYTAECEQTVEEAGFLCAVTTEPGKCyp 323 Ruminococcus lac...
ZP_07670977 168 LHHkdkngfr----inqlsnkQLRKDTEQAAEQGS--------IAYYAYPYGKYNKRIQKILQEQGTRLAFGYNENRKak 235 Erysipelotrichac...
ZP_07831991 168 LHHknadgfr----idqlndeQLQRDTEQAAKQGS--------ITYYAYPYGKYNKRIQKILNDNGTRLAFGYNENRKak 235 Clostridium sp. ...
Feature 1                             
P31666      379 -gDNPLLLKRLYILRTDSLETM 399 Escherichia coli K-12
EGQ27022    357 -gDSPFHLKRQRVHSGMSISDF 377 Sporosarcina newyorkensis 2681
YP_076179   201 -dHDPLRLNRLVVYPGTDECAF 221 Symbiobacterium thermophilum IAM 14863
ZP_07833041 371 -gMDKLQLPRVRIFGDADIQQF 391 Clostridium sp. HGF2
ZP_06160872 367 -gDNPYTLPRIRIFGESPLDSF 387 Slackia exigua ATCC 700122
ZP_02861896 388 -gDDPLLLNRVRMNYGQSLDDF 408 Anaerofustis stercorihominis DSM 17244
ZP_03634566 392 -gMDLYRLPRIRVTGGAGLDRF 412 Holdemania filiformis DSM 12042
ZP_03167620 324 -gDDPYALTRVRMLGSQSLDQF 344 Ruminococcus lactaris ATCC 29176
ZP_07670977 236 rsDDSYALPRFNVNAYTRLDVF 257 Erysipelotrichaceae bacterium 3_1_53
ZP_07831991 236 rsDDSYALPRFNVNAYTRLDVF 257 Clostridium sp. HGF2

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