Conserved Protein Domain Family
CE4_PelA_like_C

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cd10922: CE4_PelA_like_C 
C-terminal Putative NodB-like catalytic domain of PelA-like uncharacterized hypothetical proteins found in bacteria
This family is represented by a protein PelA of unknown function that is encoded by a gene in the pelA-G gene cluster for pellicle production and biofilm formation in Pseudomonas aeruginosa. PelA and most of the family members contain a domain of unknown function, DUF297, in the N-terminus and a C-terminal domain that shows high sequence similarity to the catalytic domain of the six-stranded barrel rhizobial NodB-like proteins, which remove N-linked or O-linked acetyl groups from cell wall polysaccharides and belong to the larger carbohydrate esterase 4 (CE4) superfamily.
Statistics
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PSSM-Id: 200548
Aligned: 14 rows
Threshold Bit Score: 276.895
Created: 1-Jun-2011
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative active
Feature 1:putative active site [active site]
Evidence:
  • Comment:based on similarity to other CE4 superfamily members

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                   ##                                                                    
YP_985093     507 NGRRLLLAHVDGDGFpslae-----fpgspLAAQVLLKEIFEKYRi-PQTMSVIEAEVapdgl--ypglSPRMEEVARKM 578  Acidovorax sp...
NP_251754     518 NGRRIATVHIDGDGFvsrae-----vpgspYAGQQVLEDFIKPYPf-LTSVSVIEGEVgpkgm--yphlARELEPIARRI 589  Pseudomonas a...
ZP_05083423   232 MGRRIYFSHIDGDGWnnvsyaa-kyrdqqvLSGEVMLRELIEPYPdlPVTYGLVTADVdks-----eggDDQGVGLVREL 305  Pseudovibrio ...
EES53933      759 NGNRIFYSQVDGDAFetlsh-----yrrrrMAAEVLYREIFRPTPl-PFTVSVITSQIdpa-----vqgSRARVYWARKI 827  Leptospirillu...
ADU96776      482 SGSRILTVHLDGDGFadksa-----vvpgeYTGEVLRDKIFKVFKv-PHTVSVIVGELdphgl--ypdkAERLMAVARSI 553  Thermovibrio ...
CAZ87962      531 TGRRAFFVHFDGDGWpnacd-----qpgspLACEVLVTEFLEKYKv-PTLASVIIGEIshegl--ypklADQSQKWAKRM 602  Thiomonas sp....
AEK56692      493 SGRRLFMAHTDGDGFvsrad-----fppyhIAGQVYMDRILKKYRl-PFTGSVIVGDLlpgdrglypalAPLGTQVAREL 566  Acidithiobaci...
YP_002992282  261 NGKRVAFAHIDGDGFvgyte-----vdqnkVCGEIVMERIFERYDf-PNSASVIAGEInpd-----vkgSLDNVELAKTL 329  Desulfovibrio...
YP_413113     514 NGRRLLLVQIDGDGAgnkae-----ipgtpLAIKVIQDQFLQKYNl-PSTVSIIEGETanrg---ssdkVTEAEKIAQDI 584  Nitrosospira ...
YP_866872     265 SGRRIFYSHIDGDAWrsetrikkyqrkgmrYVSDVILEEVVKAYPdlPVTVAPVVADLdpt-----wfgRPTFIKTAREI 339  Magnetococcus...
Feature 1                   #   #                                                                 
YP_985093     579 FRLPHIEVGSHTYSHPFLWdanvqhg------------------------------------------------------ 604  Acidovorax sp...
NP_251754     590 FADDKVEVASHTFSHPFFWqpqlaeqg----------------------------------------------------- 616  Pseudomonas a...
ZP_05083423   306 FALPQVEVASHTHSHPFHWafyrdydrekelaliqeknvaktpvte----------------------gpvswlsrrffg 363  Pseudovibrio ...
EES53933      828 FALPNVEAGSHTFSHPFYWvptkk-------------------------------------------------------- 851  Leptospirillu...
ADU96776      554 FALPNVEPASHTYSHPFNWwdiylmslgkk-------------------------------------------------- 583  Thermovibrio ...
CAZ87962      603 YALPWVEVGSHTWSHPFNWvaasethsr---------------------------------------------------- 630  Thiomonas sp....
AEK56692      567 FRLPYVEIGSHMWSHPFNWpaiea-------------------------------------------------------- 590  Acidithiobaci...
YP_002992282  330 FEMENVETSSHSYTHPYAWnaktres------------------------------------------------------ 355  Desulfovibrio...
YP_413113     585 FKLNHVEIASHSYSHPSAWfpknt-------------------------------------------------------- 608  Nitrosospira ...
YP_866872     340 FSYKHVEAGSHTYSHPLQWsffenpdpeaelpflhlypqrdqtdmvdyllrsvglrkneasatpdsqgwkqvaaralrkk 419  Magnetococcus...
Feature 1                                                     ###                                 
YP_985093     605 -------lfkenpeAAQSLVVPGYTMDLEREIVGSshYINERLAPSGKPVKVLQWTGDTaPSARALEITHRAGLLNINGG 677  Acidovorax sp...
NP_251754     617 -------enfeaqyGYKMAIPGYDKVDFVREVIGArdYIEQRLTTPRKPVKMIFWSGDAlPDAATIKLAYDAGLMNVNGG 689  Pseudomonas a...
ZP_05083423   364 esgkssfkkylaqnVAMPRYYMRKPFSLIGEIGGSl-QQAERYAPVGKEAKLFLWSGDTqPFEEALAYTRELGVYNMNGG 442  Pseudovibrio ...
EES53933      852 ----------qkdeGPIHIEIPHYRLDLKTEIRGSidYINEHLLPPGKTVRLLQWSGDTrPGPAALKELVGTGVDNLNGS 921  Leptospirillu...
ADU96776      584 ---lpppnpkelpyGYHLNIPGYTKVSISKEIDYSvhFIDRYLTPPGKEVKDFLWSGDCdPPAPVVKRVYDLKLYNVNGG 660  Thermovibrio ...
CAZ87962      631 ------gketknfpYGNYLPLPNYTFSTKSNVVDAaqYIDDKLCPPGKKCNMILWPGDCnPPDEAVAMAYETGLGNINGG 704  Thiomonas sp....
AEK56692      591 ----------gkdyPGINLPVPGYTFSPYMEAVGAakWIDKHLAPPGKQVVIDQWSGDCePDAQVVGLAYGAGLENINGG 660  Acidithiobaci...
YP_002992282  356 -------keyaedfVVGQYEVSGYEFDAHYEIVGScdYISENLAPVEKPCRVLFWSGMCePTEEQVGIAENAGILNMNGG 428  Desulfovibrio...
YP_413113     609 ---------idadgDEYQLSVDGYGFDLHREIAGSveYINNTLAPENKRARVFLWTGDGlASREALALARSLGLENMNGG 679  Nitrosospira ...
YP_866872     420 neqakketlqlfnhYDIPRAFAVKPFDLNLEIQGSf-DFINTLLPAKKRVEVLQWSGNCvPFEAAVRQTREAGVQNLNGG 498  Magnetococcus...
Feature 1                                    #                                                    
YP_985093     678 DTSISRANPSLTaVGALGIRKGGFLQVYAPitNENIYTNLWTGPyyGFERAIETFEMTDSPRRIKPVGIYYHTYSASKPA 757  Acidovorax sp...
NP_251754     690 NTALTRAFPSLTgLYPLIRPTRGGVQYYAPiiNENVYTNLWQGPyyGFRGVIDTFALTDSPRRLRGLHLYYHFYSGTKQA 769  Pseudomonas a...
ZP_05083423   443 DTRFDRDWPSLSyVAPLSRQVGAERQIYAVasNENTYTNDWTGPfyGFSQLHQTVDNTESPIRLRPYNVYYHTYSAEHDA 522  Pseudovibrio ...
EES53933      922 DTRFDDNAPSYTfVFPYFRRVGPYLQYFNSdvNDYILTNDWKGPyyGYLNVTKTFLRTDRPRRVDPIDVYFHFYAGQRES 1001 Leptospirillu...
ADU96776      661 DTTISDTFPYLCrVSPMGINKAGYFQVYAPfqNENVYTNEWTVKd-GYLRVISGFKLTDSPRRLKPISIYYHFYSGEDPS 739  Thermovibrio ...
CAZ87962      705 GAPISKTRPTLSdVWPMGIPKGKYFQVYAAqsNEEVFTHNWQGPyfGFERVVESYQMTDSPRRIKPIDLYYHPYIVTKAA 784  Thiomonas sp....
AEK56692      661 TSYISKKNPSITaVPPIGIFRGKWLQVFAPdaNEDYFTNQWHGPywGYIDVIQTFEMTDKPHRLKPIDIYTHWYTATKLA 740  Acidithiobaci...
YP_002992282  429 DTVFDARRNSYFgVSPLYRALGKYNQIYTGqaNENILTNLWSGPyfGFRNIVDTMKRTGSPRRIMPIDIYYHFYSGEKFS 508  Desulfovibrio...
YP_413113     680 GATISNDEKTVTrVPPLGYVMDDQLQLYAPmaSEHVYTNRWQGPfhAFSRVVETMQLTDRPLRLKPLHIHYHFYSGSKTD 759  Nitrosospira ...
YP_866872     499 DSRFDPEYPSVAwLSPFGRYVGDEVQIYASasNENTYTDLWTDRffGFMHLVETFKNTETPRRLQPMNIYYHMYSGERVA 578  Magnetococcus...
Feature 1                        
YP_985093     758 ALkALKKVYDWALAQ 772  Acidovorax sp. JS42
NP_251754     770 SIrTMHQIYAAMQAE 784  Pseudomonas aeruginosa PAO1
ZP_05083423   523 SLrAVKKHLDRARDG 537  Pseudovibrio sp. JE062
EES53933     1002 ALnALRQVLGWVQRQ 1016 Leptospirillum ferrodiazotrophum
ADU96776      740 AFnALKAVYRWALSQ 754  Thermovibrio ammonificans HB-1
CAZ87962      785 GAkSLHTVYQWVLKQ 799  Thiomonas sp. 3As
AEK56692      741 SLsALERVYDWVLKQ 755  Acidithiobacillus caldus SM-1
YP_002992282  509 SLkALEDVYEWVLTQ 523  Desulfovibrio salexigens DSM 2638
YP_413113     760 SInALKSVYEWTVKQ 774  Nitrosospira multiformis ATCC 25196
YP_866872     579 SLkALRHNLDYARSR 593  Magnetococcus sp. MC-1

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