Conserved Protein Domain Family
Csn1
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cd09643: Csn1 
CRISPR/Cas system-associated protein Cas9
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Very large protein containing McrA/HNH-nuclease related domain and a RuvC-like nuclease domain; signature gene for type II
Links
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Statistics
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PSSM-Id: 187774
Aligned: 11 rows
Threshold Bit Score: 695.706
Created: 5-Feb-2010
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
AAS10822        7 DYFLGLDVGTGSVGWAVTDTDYKllk------------anrKDLWGMRCFETAETAE---VRRLHRGARRRIERRKKRIK 71   Treponema den...
CAE10505        3 ERILGVDLGISSLGWAIVEYDKDdeaanr------iidcgvRLFTAAETPKKKESPNk--ARREARGIRRVLNRRRVRMN 74   Wolinella suc...
AAK03211        7 SYILGLDLGIASVGWAVVEINENedpigl-------idvgvRIFERAEVPKTGESLAl--SRRLARSTRRLIRRRAHRLL 77   Pasteurella m...
AAN59070        4 PYSIGLDIGTNSVGWAVVTDDYKvpakkmkvlgntdkshieKNLLGALLFDSGNTAE---DRRLKRTARRRYTRRRNRIL 80   Streptococcus...
AAK33936        4 KYSIGLDIGTNSVGWAVITDEYKvpskkfkvlgntdrhsikKNLIGALLFDSGETAE---ATRLKRTARRRYTRRKNRIC 80   Streptococcus...
AAM99780        4 PYSIGLDIGTNSVGWSIITDDYKvpakkmrvlgntdkeyikKNLIGALLFDGGNTAA---DRRLKRTARRRYTRRRNRIL 80   Streptococcus...
YP_002342100   10 NYILGLDIGIASVGWAMVEIDEDenpicl-------idlgvRVFERAEVPKTGDSLAm--ARRLARSVRRLTRRRAHRLL 80   Neisseria men...
YP_001450662    3 GLVLGLDIGIASVGVGILEKDTG------------------KIIHASSRLFPAATADnnvERRSNRQGRRLNRRKKHRSV 64   Streptococcus...
NP_853456      14 EVTIGLDLGVGSVGWAIVDNETNi-----------------IHHLGSRLFSQAKTAE---DRRSFRGVRRLIRRRKYKLK 73   Mycoplasma ga...
YP_002344900    2 ARILAFDIGISSIGWAFSENDELkdc-------------gvRIFTKVENPKTGESLAl--PRRLARSARKRLARRKARLN 66   Campylobacter...
NP_472073       4 PYTIGLDIGTNSVGWAVLTDQYDlvkrkmkiagdsekkqikKNFWGVRLFDEGQTAA---DRRMARTARRRIERRRNRIS 80   Listeria inno...

AAS10822       72 LLQELFSQEIAKTDEGFFqrmkespfyaedktilqentlfndkdfadktyhkaypTINHLIKAWIENKVKPDPrlLYLAC 151  Treponema den...
CAE10505       75 MIKKLFLRAGLIQDVDLDgeggmfy------------------------skanraDVWELRHDGLYRLLKGDE--LARVL 128  Wolinella suc...
AAK03211       78 LAKRFLKREGILSTIDLEkgl--------------------------------pnQAWELRVAGLERRLSAIE--WGAVL 123  Pasteurella m...
AAN59070       81 YLQEIFSEEMGKVDDSFFhrledsflvtedkrgerh--pifgnleeevkyhenfpTIYHLRQYLADNPEKVDLrlVYLAL 158  Streptococcus...
AAK33936       81 YLQEIFSNEMAKVDDSFFhrleesflveedkkherh--pifgnivdevayhekypTIYHLRKKLVDSTDKADLrlIYLAL 158  Streptococcus...
AAM99780       81 YLQEIFAEEMSKVDDSFFhrledsflveedkrgsky--pifatlqeekdyhekfsTIYHLRKELADKKEKADLrlIYIAL 158  Streptococcus...
YP_002342100   81 RARRLLKREGVLQAADFDengli---------------------------kslpnTPWQLRAAALDRKLTPLE--WSAVL 131  Neisseria men...
YP_001450662   65 RLQDLFEGYGLLTDFSKVsm---------------------------------nlNPYQLRVQGMENQLTNEE--LFVAL 109  Streptococcus...
NP_853456      74 RFVNLIWKYNSYFGFKNKedilnnyq----------------------eqqklhnTVLNLKLEALNAKIDPKA--LSWIL 129  Mycoplasma ga...
YP_002344900   67 HLKHLIANEFKLNYEDYQsfdeslak----------------------aykgsliSPYELRFRALNELLSKQD--FARVI 122  Campylobacter...
NP_472073      81 YLQGIFAEEMSKTDANFFcrlsdsfyvdnekrnsrh--pffatieeeveyhknypTIYHLREELVNSSEKADLrlVYLAL 158  Listeria inno...

AAS10822      152 HNIIKKRGHFLFEGdfdsenqfdtsiqalfeylredmevdidadsqkvkeilkdsslknsekqsrlnkilglkpsdkqkk 231  Treponema den...
CAE10505      129 IHIAKHRGYKFIGDdea--------------------------------------------------------------- 145  Wolinella suc...
AAK03211      124 LHLIKHRGYLSKRKnesqt------------------------------------------------------------- 142  Pasteurella m...
AAN59070      159 AHIIKFRGHFLIEGkfdtrnndvqrlfqeflavydntfensslqeqnvqveeiltdkisksakkdrvlklfpneksngrf 238  Streptococcus...
AAK33936      159 AHMIKFRGHFLIEGdlnpdnsdvdklfiqlvqtynqlfeenpinasgvdakailsarlsksrrlenliaqlpgekknglf 238  Streptococcus...
AAM99780      159 AHIIKFRGHFLIEDdsfdvrntdiskqyqdfleifnttfenndllsqnvdveailtdkisksakkdrilaqypnqkstgi 238  Streptococcus...
YP_002342100  132 LHLIKHRGYLSQRKneget------------------------------------------------------------- 150  Neisseria men...
YP_001450662  110 KNIVKRRGISYLDDas---------------------------------------------------------------- 125  Streptococcus...
NP_853456     130 HDYLKNRGHFYEDNrdfn-------------------------------------------------------------- 147  Mycoplasma ga...
YP_002344900  123 LHIAKRRGYDDIKNsdd--------------------------------------------------------------- 139  Campylobacter...
NP_472073     159 AHIIKYRGNFLIEGaldtqntsvdgiykqfiqtynqvfasgiedgslkklednkdvakilvekvtrkeklerilklypge 238  Listeria inno...

AAS10822      232 ait--------nlisgnkinfadlydnpdlkdaeknsisfskddfdalsddlasilgdsfelllkakavyncsvlskvig 303  Treponema den...
CAE10505      146 -----------------------------------------------------------------------------dee 148  Wolinella suc...
AAK03211      143 ----------------------------------------------------------------------------nnke 146  Pasteurella m...
AAN59070      239 aefl------klivgnqadfkkhfeleekaplqfskdtyeeelevllaqigdnyaelflsakklydsillsgiltvtdvg 312  Streptococcus...
AAK33936      239 gnli------alslgltpnfksnfdlaedaklqlskdtydddldnllaqigdqyadlflaaknlsdaillsdilrvntei 312  Streptococcus...
AAM99780      239 faefl-----klivgnqadfkkyfnledktplqfakdsydedlenllgqigdefadlfsaakklydsvllsgiltvidls 313  Streptococcus...
YP_002342100  151 ----------------------------------------------------------------------------adke 154  Neisseria men...
YP_001450662  126 -------------------------------------------------------------------------------e 126  Streptococcus...
NP_853456     148 -----------------------------------------------------------------------------vyp 150  Mycoplasma ga...
YP_002344900  140 ------------------------------------------------------------------------------ke 141  Campylobacter...
NP_472073     239 ksagmfaqfislivgskgnfqkpfdlieksdiecakdsyeedlesllaligdeyaelfvaaknaysavvlssiitvaete 318  Listeria inno...

AAS10822      304 DEQYLSFa-----kVKIYEKHKTDLTKLKNVIKKHFPKDYKKvfgynkneknnnnysgyvgvcktkskkliinnsvnqed 378  Treponema den...
CAE10505      149 SGKVKKAg-----vVLRQNFEAAGCRTVGEWLWRERGANGKK-------------------------------------- 185  Wolinella suc...
AAK03211      147 LGALLSGv-----aQNHQLLQSDDYRTPAELALKKFAKEEGHi------------------------------------- 184  Pasteurella m...
AAN59070      313 TKAPLSAs-----mIQRYNEHQMDLAQLKQFIRQKLSDKYNEvfsdvskdgyagyidgktnqeafyk------------- 374  Streptococcus...
AAK33936      313 TKAPLSAs-----mIKRYDEHHQDLTLLKALVRQQLPEKYKEiffdqskngyagyidggasqeefyk------------- 374  Streptococcus...
AAM99780      314 TKAPLSAs-----mIQRYDEHREDLKQLKQFVKASLPEKYQEifadsskdgyagyiegktnqeafyk------------- 375  Streptococcus...
YP_002342100  155 LGALLKGv-----aDNAHALQTGDFRTPAELALNKFEKESGHi------------------------------------- 192  Neisseria men...
YP_001450662  127 DGGTVSSdy----gKAVEENRKLLAEKTPGQIQLERFEKYGQlrgdf--------------------------------- 169  Streptococcus...
NP_853456     151 TEELANYfdefgyyKGIIDSKNDDDDKLEEGLTKYKFSNQHWl------------------------------------- 193  Mycoplasma ga...
YP_002344900  142 KGAILKA-------IKQNEEKLANYQSVGEYLYKEYFQKFKEnske---------------------------------- 180  Campylobacter...
NP_472073     319 TNAKLSAs-----mIERFDTHEEDLGELKAFIKLHLPKHYEEifsntekhgyagyidgktkqadfyk------------- 380  Listeria inno...

AAS10822      379 fykflktilsakseikevndilteietgtflPKQISKSNAEIPYQLRKMELEKILSNAEkhfsflkqkdekglshsekii 458  Treponema den...
CAE10505      186 -------------------------------RNKHGDYEISIHRDLLVEEVEAIFVAQQ--------------------- 213  Wolinella suc...
AAK03211      185 -------------------------------RNQRGAYTHTFNRLDLLAELNLLFAQQH--------------------- 212  Pasteurella m...
AAN59070      375 ------ylkgllnkiegsgyfldkieredflRKQRTFDNGSIPHQIHLQEMRAIIRRQAefypfladn-------qdrie 441  Streptococcus...
AAK33936      375 ------fikpilekmdgteellvklnredllRKQRTFDNGSIPHQIHLGELHAILRRQEdfypflkdn-------rekie 441  Streptococcus...
AAM99780      376 ------ylsklltkqedsenflekiknedflRKQRTFDNGSIPHQVHLTELKAIIRRQSeyypflken-------qdrie 442  Streptococcus...
YP_002342100  193 -------------------------------RNQRGDYSHTFSRKDLQAELILLFEKQK--------------------- 220  Neisseria men...
YP_001450662  170 ---------------------------tveeNGEKHRLINVFSTSAYRKEAERILRKQQefnskitde------fiedyl 216  Streptococcus...
NP_853456     194 ------------------------------eEVKKVLSNQTGLPEKFKEEYESLFSYVRnyseg---------------p 228  Mycoplasma ga...
YP_002344900  181 ---------------------------ftnvRNKKESYERCIAQSFLKDELKLIFKKQR--------------------- 212  Campylobacter...
NP_472073     381 ------ymkmtleniegadyfiakiekenflRKQRTFDNGAIPHQLHLEELEAILHQQAkyypflken-------ydkik 447  Listeria inno...

AAS10822      459 mllTFKIPYYiGPINDNHKKFFPDRCwvvkkekspsgkttpwnffdhidkektaeafITSRTNFCTYLVGESVLPKSSLL 538  Treponema den...
CAE10505      214 ---EMRSTIAtDALKAAYREIAFFVRpm---------------------------qrIEKMVGHCTYFPEERRAPKSAPT 263  Wolinella suc...
AAK03211      213 ---QFGNPHCkEHIQQYMTELLMWQKpals------------------------geaILKMLGKCTHEKNEFKAAKHTYS 265  Pasteurella m...
AAN59070      442 kllTFRIPYYvGPLARGKSDFAWLSRksadkitpwnfd-------eivdkessaeafINRMTNYDLYLPNQKVLPKHSLL 514  Streptococcus...
AAK33936      442 kilTFRIPYYvGPLARGNSRFAWMTRkseetitpwnfe-------evvdkgasaqsfIERMTNFDKNLPNEKVLPKHSLL 514  Streptococcus...
AAM99780      443 kilTFRIPYYiGPLAREKSDFAWMTRktddsirpwnfe-------dlvdkeksaeafIHRMTNNDFYLPEEKVLPKHSLI 515  Streptococcus...
YP_002342100  221 ---EFGNPHVsGGLKEGIETLLMTQRpals------------------------gdaVQKMLGHCTFEPAEPKAAKNTYT 273  Neisseria men...
YP_001450662  217 iilTGKRKYYhGPGNEKSRTDYGRFRtdgtt----------------------ldniFGILIGKCTFYTEEYRASKASYT 274  Streptococcus...
NP_853456     229 gsiNSVSPYGiYHLDEKEGKVVQKYNn-----------------------------iWDKTIGKCSIFPDEYRAPKNSPI 279  Mycoplasma ga...
YP_002344900  213 ---EFGFSFS-KKFEEEVLSVAFYKRal---------------------------kdFSHLVGNCSFFTDEKRAPKNSPL 261  Campylobacter...
NP_472073     448 slvTFRIPYFvGPLANGQSEFAWLTRkadgeirpwnie-------ekvdfgksavdfIEKMTNKDTYLPKENVLPKHSLC 520  Listeria inno...

AAS10822      539 YSEYTVLNEINNLQIii------dGKNICDIKLKQKIYEDLFKKYKKIT----QKQISTFIKHEGICNKtdevii----- 603  Treponema den...
CAE10505      264 AEKFIAISKFFSTVIidn---egwEQKIIERKTLEELLDFAVSREKVEFr---HLRKFLDLSDNEIFKGlhykgkpktak 337  Wolinella suc...
AAK03211      266 AERFVWLTKLNNLRIle-----dgAERALNEEERQLLINHPYEKSKLTYa---QVRKLLGLSEQAIFKHlryske----- 332  Pasteurella m...
AAN59070      515 YEKFTVYNELTKVKYkte----qgKTAFFDANMKQEIFDGVFKVYRKVTk---DKLMDFLEKEFDEFRIvdltgl----- 582  Streptococcus...
AAK33936      515 YEYFTVYNELTKVKYvte---gmrKPAFLSGEQKKAIVDLLFKTNRKVTv---KQLKEDYFKKIECFDSveisg------ 582  Streptococcus...
AAM99780      516 YEKFTVYNELTKVRYkne----qgETYFFDSNIKQEIFDGVFKEHRKVSk---KKLLDFLAKEYEEFRIvdvigl----- 583  Streptococcus...
YP_002342100  274 AERFIWLTKLNNLRIle-----qgSERPLTDTERATLMDEPYRKSKLTYa---QARKLLGLEDTAFFKGlrygkd----- 340  Neisseria men...
YP_001450662  275 AQEFNLLNDLNNLTVp-------tETKKLSEEQKKLIIEYAKSAKTLGAstllKYIAKMIDASVDQIRGyrv-------- 339  Streptococcus...
NP_853456     280 AMIFNEINELSTIRSysiyltgwfINQEFKKAYLNKLLDLLIKTNSEKPi---DARQFKKLREETIAESigketlkdves 356  Mycoplasma ga...
YP_002344900  262 AFMFVALTRIINLLNnlk----ntEGILYTKDDLNALLNEVLKNGTLTYk---QTKKLLGLSDDYEFKGek--------- 325  Campylobacter...
NP_472073     521 YQKYLVYNELTKVRYind----qgKTSYFSGQEKEQIFNDLFKQKRKVK----KKDLELFLRNMSHVESptieg------ 586  Listeria inno...

AAS10822      604 -------------------lgidkeCTSSLKSYIELKNIFGKQvde-------isTKNMLEEIIRWATIYDEGegkt--- 654  Treponema den...
CAE10505      338 kreatlfdpneptelefdkveaekkAWISLRGAAKLREALGNEfygr-----fvaLGKHADEATKILTYYKDEg------ 406  Wolinella suc...
AAK03211      333 --------------------naesaTFMELKAWHAIRKALENQglkdtw-qdlakKPDLLDEIGTAFSLYKTD------- 384  Pasteurella m...
AAN59070      583 -------------------dkenkvFNASYGTYHDLCKILDKDfld------nskNEKILEDIVLTLTLFEDRem----- 632  Streptococcus...
AAK33936      583 ---------------------vedrFNASLGTYHDLLKIIKDKdfld-----neeNEDILEDIVLTLTLFEDRem----- 631  Streptococcus...
AAM99780      584 -------------------dkenkaFNASLGTYHDLEKILDKDfld------npdNESILEDIVQTLTLFEDRem----- 633  Streptococcus...
YP_002342100  341 --------------------naeasTLMEMKAYHAISRALEKEglkdkk-splnlSPELQDEIGTAFSLFKTD------- 392  Neisseria men...
YP_001450662  340 ----------------------dvnNKPEMHTFEVYRKMQSLEtikv-----eelPRKVLDELAHILTLNTEReg----- 387  Streptococcus...
NP_853456     357 eekle----kddhkwklkglklntnGKIQYNDLSSLAKFVHKLkqhlkldflledQYTPLDKINFLQSLYVYLgkhlrys 432  Mycoplasma ga...
YP_002344900  326 -----------------------gtYFIEFKKYKEFIKALGEHn----------lSQDDLNEIAKDITLIKDEi------ 366  Campylobacter...
NP_472073     587 ---------------------ledsFNSSYSTYHDLLKVGIKQeild-----npvNTEMLENIVKILTVFEDKrm----- 635  Listeria inno...

AAS10822      655 --------ilkTKIKAEYGKYCSDEQ--IKKILNLK-------FSGWGRLSRKFLETVTSEMPGFSEPVNIITAMRETQn 717  Treponema den...
CAE10505      407 -----------QKRRELTKLPLEAEM--VERLVKIG-------FSDFLKLSLKAIRDILPAMESGARYDEAVLMLGVPH- 465  Wolinella suc...
AAK03211      385 -----------EDIQQYLTNKVPNSV--INALLVSLn------FDKFIELSLKSLRKILPLMEQGKRYDQACREIYGHHy 445  Pasteurella m...
AAN59070      633 ----------iRKRLENYSDLLTKEQ--VKKLERRH-------YTGWGRLSAELIHGIRNKESRKTILDYLIDDGNSNRn 693  Streptococcus...
AAK33936      632 ----------iEERLKTYAHLFDDKV--MKQLKRRR-------YTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRn 692  Streptococcus...
AAM99780      634 ----------iKKRLENYKDLFTESQ--LKKLYRRH-------YTGWGRLSAKLINGIRDKESQKTILDYLIDDGRSNRn 694  Streptococcus...
YP_002342100  393 -----------EDITGRLKDRIQPEI--LEALLKHIs------FDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDHy 453  Neisseria men...
YP_001450662  388 ---------ieEAINSKLKDIFNRDQ--VLELVQFRknnsslfSKGWHNFSIKLMMELIPELYETSEEQMTILTRLGKQr 456  Streptococcus...
NP_853456     433 nrvdsanlkefSDSSRLFERVLQEQKdgLFKLFEQTdkddekiLTQTHSLSTKAMLLAITRMTNLDNDEDNQKNNDKGWn 512  Mycoplasma ga...
YP_002344900  367 -----------KLKKALAKYDLNQNQ--IDSLSKLE-------FKDHLNISFKALKLVTPLMLEGKKYDEACNELNLKV- 425  Campylobacter...
NP_472073     636 ----------iKEQLQQFSDVLDGVV--LKKLERRH-------YTGWGRLSAKLLMGIRDKQSHLTILDYLMNDDGLNRn 696  Listeria inno...

AAS10822      718 nlmELLSSEFTFTENIKkinsgfedaekqfsydglvkPLFLSPSVKKMLWQTLKLVKEISHITQa--PPKKIFIEMAKGA 795  Treponema den...
CAE10505      466 ---KEKSAILPPLNKTD--------------------IDILNPTVIRAFAQFRKVANALVRKYG---AFDRVHFELAREI 519  Wolinella suc...
AAK03211      446 --gEANQKTSQLLPAIPa-------------------QEIRNPVVLRTLSQARKVINAIIRQYG---SPARVHIETGREL 501  Pasteurella m...
AAN59070      694 fmqLINDDALSFKEEIAkaqviget----dnlnqvvsDIAGSPAIKKGILQSLKIVDELVKIMGh--QPENIVVEMAREN 767  Streptococcus...
AAK33936      693 fmqLIHDDSLTFKEDIQkaqvsgqg----dslhehiaNLAGSPAIKKGILQTVKVVDELVKVMGr-hKPENIVIEMAREN 767  Streptococcus...
AAM99780      695 fmqLINDDGLSFKSIISkaqagshs----dnlkevvgELAGSPAIKKGILQSLKIVDELVKVMGy--EPEQIVVEMAREN 768  Streptococcus...
YP_002342100  454 --gKKNTEEKIYLPPIPa-------------------DEIRNPVVLRALSQARKVINGVVRRYG---SPARIHIETAREV 509  Neisseria men...
YP_001450662  457 --sKETSKRTKYIDEKEl------------------tEEIYNPVVAKSVRQAIKIINEATKKYG---IFDNIVIEMAREN 513  Streptococcus...
NP_853456     513 f-eAIKNFDQKFIDITKtnnnlslkqdkrylddqfinDAILSPGVKRILREATKVFNAILKQFSeeyDVTKVVIELAREL 591  Mycoplasma ga...
YP_002344900  426 ---AINEDKKDFLPAFNety---------------ykDEVTNPVVLRAIKEYRKVLNALLKKYG---KVHKINIELAREV 484  Campylobacter...
NP_472073     697 lmqLINDSNLSFKSIIEkeqvttad----kdiqsivaDLAGSPAIKKGILQSLKIVDELVSVMGy--PPQTIVVEMAREN 770  Listeria inno...

AAS10822      796 Ele--pARTKTRLKILQDLYNNCKNDADaf---sSEIKDLSGKienednlRLRSDKLYLYYTQLGKCMYCGKPIEIGhv- 869  Treponema den...
CAE10505      520 Nt---kGEIEDIKESQRKNEKERKEAADwi---aETSFQVPLT-------RKNILKKRLYIQQDGRCAYTGDVIELErl- 585  Wolinella suc...
AAK03211      502 G-----KSFKERREIQKQQEDNRTKRESa----vQKFKELFSDfss-epkSKDILKFRLYEQQHGKCLYSGKEINIHrl- 570  Pasteurella m...
AAN59070      768 Qft--nQGRRNSQQRLKGLTDSIKEFGS------QILKEHPVEn-----sQLQNDRLFLYYLQNGRDMYTGEELDID--- 831  Streptococcus...
AAK33936      768 Qtt--qKGQKNSRERMKRIEEGIKELGS------QILKEHPVEn-----tQLQNEKLYLYYLQNGRDMYVDQELDIN--- 831  Streptococcus...
AAM99780      769 Qtt--nQGRRNSRQRYKLLDDGVKNLASdl--ngNILKEYPTDn-----qALQNERLFLYYLQNGRDMYTGEALDID--- 836  Streptococcus...
YP_002342100  510 G-----KSFKDRKEIEKRQEENRKDREKa----aAKFREYFPNfvg-epkSKDILKLRLYEQQHGKCLYSGKEINLGrl- 578  Neisseria men...
YP_001450662  514 Ne---eDAKKDYIKRQKANQDEKNAAMEkaafqyNGKKELPDNifh--ghKELTTKIRLWHQQGEKCLYTGKNIPISdli 588  Streptococcus...
NP_853456     592 SeekelENTKNYKKLIKKNGDKISEGLKalgiaeDKIEEILKS-------PTKSYKVLLWLQQDHIDPYSQKEIAFDdil 664  Mycoplasma ga...
YP_002344900  485 G-----KNHSQRAKIEKEQNENYKAKKDa----eLECEKLGLKi-----nSKNILKLRLFKEQKEFCAYSGEKIKISdl- 549  Campylobacter...
NP_472073     771 Qtt--gKGKNNSRPRYKSLEKAIKEFGS------QILKEHPTDn-----qELRNNRLYLYYLQNGKDMYTGQDLDIH--- 834  Listeria inno...

AAS10822      870 fDTSNYDIDHIYPQSKIKDDSISNRVLVCSSCNKNKEDKYPLKsEIQs-KQRGFWNFLQRNNFISLE-------KLNR-- 939  Treponema den...
CAE10505      586 fDEGYCEIDHILPRSRSADDSFANKVLCLARANQQKTDRTPYE-WFG--HDAARWNAFETRTSAPSNrvrtgkgKIDR-- 660  Wolinella suc...
AAK03211      571 nEKGYVEIDHALPFSRTWDDSFNNKVLVLASENQNKGNQTPYE-WLQgkINSERWKNFVALVLGSQCsa----aKKQR-- 643  Pasteurella m...
AAN59070      832 -YLSQYDIDHIIPQAFIKDNSIDNRVLTSSKENRGKSDDVPSK-DVVr-KMKSYWSKLLSAKLITQR-------KFDNlt 901  Streptococcus...
AAK33936      832 -RLSDYDVDHIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVPSE-EVVk-KMKNYWRQLLNAKLITQR-------KFDNlt 901  Streptococcus...
AAM99780      837 -NLSQYDIDHIIPQAFIKDDSIDNRVLVSSAKNRGKSDDVPSL-EIVk-DCKVFWKKLLDAKLMSQR-------KYDNlt 906  Streptococcus...
YP_002342100  579 nEKGYVEIDHALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYE-YFNgkDNSREWQEFKARVETSRFpr----sKKQRi- 652  Neisseria men...
YP_001450662  589 hNQYKYEIDHILPLSLSFDDSLSNKVLVLATANQEKGQRTPFQ-ALD--SMDDAWSYREFKSYVKDSkll-snkKKDYl- 663  Streptococcus...
NP_853456     665 tKTEKTEIDHIIPYSISFDDSSSNKLLVLAESNQAKSNQTPYE-FINsgKAEITWEVYEAYCHKFKNgd---ssLLDStq 740  Mycoplasma ga...
YP_002344900  550 qDEKMLEIDHIYPYSRSFDDSYMNKVLVFTKQNQEKLNQTPFE-AFG--NDSAKWQKIEVLAKNLPT-------KKQKr- 618  Campylobacter...
NP_472073     835 -NLSNYDIDHIVPQSFITDNSIDNLVLTSSAGNREKGDDVPPL-EIVr-KRKVFWEKLYQGNLMSKR-------KFDYlt 904  Listeria inno...

AAS10822      940 LTRAt--pISDDet----aKFIARQLVETRQATKVAAKVLEKMFP-------------------ETKIVYSKAETVSMFR 994  Treponema den...
CAE10505      661 LLKKn---FDENse----mAFKDRNLNDTRYMARAIKTYCEQYWVfkn-------------shtKAPVQVRSGKLTSVLR 720  Wolinella suc...
AAK03211      644 LLTQv---IDDN-------KFIDRNLNDTRYIARFLSNYIQENLLlvg--------------knKKNVFTPNGQITALLR 699  Pasteurella m...
AAN59070      902 KAERg--gLTDDdk----aGFIKRQLVETRQITKHVARILDERFNtetden--------nkkirQVKIVTLKSNLVSNFR 967  Streptococcus...
AAK33936      902 KAERg--gLSELdk----aGFIKRQLVETRQITKHVAQILDSRMNtkyden--------dklirEVKVITLKSKLVSDFR 967  Streptococcus...
AAM99780      907 KAERg--gLTSDdk----aRFIQRQLVETRQITKHVARILDERFNneldsk--------grrirKVKIVTLKSNLVSNFR 972  Streptococcus...
YP_002342100  653 LLQK----FDED-------GFKERNLNDTRYVNRFLCQFVADRMRltg--------------kgKKRVFASNGQITNLLR 707  Neisseria men...
YP_001450662  664 LTEEd---ISKIev---kqKFIERNLVDTRYSSRVVLNALQDFYKsh---------------qlDTTISVVRGQFTSQLR 722  Streptococcus...
NP_853456     741 RSKKfakmMKTDtsskydiGFLARNLNDTRYATIVFRDALKDYANnhlv-----------edkpMFKVVCINGGVTSFLR 809  Mycoplasma ga...
YP_002344900  619 ILDKn---YKDKeq----kNFKDRNLNDTRYIARLVLNYTKDYLDflplsddentklndtqkgsKVHVEAKSGMLTSALR 691  Campylobacter...
NP_472073     905 KAERg--gLTEAdk----aRFIHRQLVETRQITKNVANILHQRFNyekddh--------gntmkQVRIVTLKSALVSQFR 970  Listeria inno...

AAS10822      995 NKFD----IVKCREINDFHHAHDAYLNIVVGNVYNTKFTNNPw--NFIKEKRDNPKI----------------------- 1045 Treponema den...
CAE10505      721 YQWG----LESKDRESHTHHAVDAIIIAFSTQGMVQKLSEYY---RFKETHREKERPk---------------------- 771  Wolinella suc...
AAK03211      700 SRWG----LIKARENNNRHHALDAIVVACATPSMQQKITRFI---RFKEVHPYKIENryemvdqes-------------- 758  Pasteurella m...
AAN59070      968 KEFE----LYKVREINDYHHAHDAYLNAVIGKALLGVYPQLEpefVYGDYPHFHGHKenkata----------------- 1026 Streptococcus...
AAK33936      968 KDFQ----FYKVREINNYHHAHDAYLNAVVGTALIKKYPKLEsefVYGDYKVYDVRKmiakseqeig------------- 1030 Streptococcus...
AAM99780      973 KEFG----FYKIREVNNYHHAHDAYLNAVVAKAILTKYPQLEpefVYGDYPKYNSYKtrksat----------------- 1031 Streptococcus...
YP_002342100  708 GFWG----LRKVRAENDRHHALDAVVVACSTVAMQQKITRFV---RYKEMNAFDGKTidketgev--------------- 765  Neisseria men...
YP_001450662  723 RKWG----IEKSRETYHHHAVDALIIAASSQLRLWKKHSNPLi--AYKEGQFVDSETgeivslsd--------------- 781  Streptococcus...
NP_853456     810 KNFDpkswYAKKDRDKNIHHAVDASIISIFSNETKTLFNQLT---KFADYKLFKNTDgswkkidpktgvvsevtdenwkq 886  Mycoplasma ga...
YP_002344900  692 HTWG----FSAKDRNNHLHHAIDAVIIAYANNSIVKAFSDFK---KEQESNSAELYAkkiseld---------------- 748  Campylobacter...
NP_472073     971 KQFQ----LYKVRDVNDYHHAHDAYLNGVVANTLLKVYPQLEpefVYGDYHQFDWFKankata----------------- 1029 Listeria inno...

AAS10822     1046 ----------ADTYNYYKVF 1055 Treponema denticola ATCC 35405
CAE10505      772 ---------lAVPLANFRDA 782  Wolinella succinogenes
AAK03211      759 --geiisphfPEPWAYFRQE 776  Pasteurella multocida subsp. multocida str. Pm70
AAN59070     1027 -----kkffySNIMNFFKKD 1041 Streptococcus mutans UA159
AAK33936     1031 -katakyffySNIMNFFKTE 1049 Streptococcus pyogenes M1 GAS
AAM99780     1032 ----eklffySNIMNFFKTK 1047 Streptococcus agalactiae 2603V/R
YP_002342100  766 ---lhqkthfPQPWEFFAQE 782  Neisseria meningitidis Z2491
YP_001450662  782 --eeykelvfKAPYDHFVDT 799  Streptococcus gordonii str. Challis substr. CH1
NP_853456     887 irvrnqvseiAKVIDKYIQD 906  Mycoplasma gallisepticum R
YP_002344900  749 ---yknkrkfFEPFSGFRQK 765  Campylobacter jejuni subsp. jejuni NCTC 11168
NP_472073    1030 -----kkqfyTNIMLFFAQK 1044 Listeria innocua Clip11262
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