Conserved Protein Domain Family
LPLAT_AAK14816-like

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cd07992: LPLAT_AAK14816-like 
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like
Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized glycerol-3-phosphate acyltransferases such as the Plasmodium falciparum locus AAK14816 putative acyltransferase, and similar proteins.
Statistics
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PSSM-Id: 153254
View PSSM: cd07992
Aligned: 20 rows
Threshold Bit Score: 175.143
Threshold Setting Gi: 171910163
Created: 5-Oct-2009
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative
Feature 1:putative acyl-acceptor binding pocket
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                             #  #  #                   ####             
AAK14816       8 IRWLCkvivksVFRDVNVINpenv--plygSVIFVGNHNNQFiDACVLian----ipRQVKFIVAEKSMr-rAVIGKLAS 80  malaria parasit...
XP_001879312  10 LRKVSdwtvtgYYSDCVVEGgenv--petgPLIIASTHHNELiDIAALtati--pyrRHVSFWAKSTMFa-nPITRAILE 84  Laccaria bicolo...
ZP_02925633   32 HRLISw----lYFDRVTVTGrehlpapdagPVLFLCLHRNGAvDAFVYhs-----llAPTRFMVSVQLCr--SFFGRLFF 100 Verrucomicrobiu...
ZP_02959629   20 YRIVSstirriYYPNCSLVGhvplq-qtnkPTLFLCSHRNSAfDGYLTlk-----vsPLGQALASIQLLn--SFIMRLYF 91  Providencia stu...
YP_002759560  48 VRALArrclhwSFREVHLFGadqv--paegPLLLIGNHPNDLpDVLQGffv----trRPLRYIATLSAAs-sWPARKVYE 120 Gemmatimonas au...
XP_001877801  14 IRLLFrfvlkiFYGTIVIEGidlvp-etgkPCIVCANHSNSLtDALLLvtsipskrrNMLRLTAKATQFghrTFTSWLIE 92  Laccaria bicolo...
XP_822562    137 IDFFMwvlmniYFREVVVVNeksi--pktgGVVFYGNHQNQFiDAMMIran----cgRPVRFVMAEKSFq-rPIIGLFGH 209 Trypanosoma bru...
XP_760992     31 MRSIGdlslpvFFRSLHISGlhhvp-ptntPLIVCSNHPNTIlDVAMLashm--rerRPLHFWAKSDFFh-nRLLGFILT 106 Ustilago maydis...
XP_001830157  17 IRFLAylsshsFFHEIRVIGeenv--pkdgPIIVTATHHNMMlDPVILsvtf--phkRKLNYWSKAQLFk-nPAVAWILY 91  Coprinopsis cin...
NP_596450     10 CLWILsilidfFFREVKTRGsfrvp-rkgpLILVAAPHANQFvDPLILmlqlrrevgRRTSILVAAKSYr-qRFIGLMSR 87  fission yeast
Feature 1                                                                                        
AAK14816      81 vigCISVKRPQDlkfkgighicwnkgdvkitgintrfrldvqigdklliqnkm-------fpvvkiesetelliqevini 153 malaria parasit...
XP_001879312  85 ssgAIPVRRNPNngsgssakt----------------------------------------------------------- 105 Laccaria bicolo...
ZP_02925633  101 s--GIQVVRDKDrartpda------------------------------------------------------------- 117 Verrucomicrobiu...
ZP_02959629   92 t--GIPVVRKKDkerlgis------------------------------------------------------------- 108 Providencia stu...
YP_002759560 121 glgVIPVVRVRDaraerrkgt----------------------------------------------------------- 141 Gemmatimonas au...
XP_001877801  93 sagTVPIKRRKDsadgk--------------------------------------------------------------- 109 Laccaria bicolo...
XP_822562    210 mtdAVPVIRPQDaplnsgegrlirmdgdmiygegtkftmclsdrdviiwyredvk----ctaqvlkinsdtvlqltmpva 285 Trypanosoma bru...
XP_760992    107 ssgNISVDRKNKsn------------------------------------------------------------------ 120 Ustilago maydis...
XP_001830157  92 ssgNIPVDRKSKdr------------------------------------------------------------------ 105 Coprinopsis cin...
NP_596450     88 afgAIPVERAQDlairgegkifvvaegdktaihgkdtlftkhsvgdtlllpnnygsshiasiksdtllyvkrefrgedae 167 fission yeast
Feature 1                                                 ###                                    
AAK14816     154 ecedkmngvpfkiipkinqteVYNLVTNSLKnGDTIGIFPEGGSHdrtnLLPLKPGVAIMTLcala---------dgieD 224 malaria parasit...
XP_001879312 106 ------------nngdpsrstLFRESSAALAaGQVIGVFPEGTSYtsyrILQVLPGAAWAAVeflrsq-----qrgvktG 168 Laccaria bicolo...
ZP_02925633  118 --------------drinreaMGECLRLLLQ-GGRLTIFPEGTSTlgpqHLPFRAGAVHLIQdfld---------sgrrD 173 Verrucomicrobiu...
ZP_02959629  109 ---------------assfenPVDAGVEHLKaGGSLFLFPEGSSEwghrPLPYQRGAARIIRtlls----------qqiE 163 Providencia stu...
YP_002759560 142 -------------dmkavnaaAGNLVGEALLaGHAVGVFPEGGVHnvpyVGKPRAGVVKMLFeysd---------sgakD 199 Gemmatimonas au...
XP_001877801 110 ----------------adntdAMLKLMEALElGDAICLFPEGMSRfhptIAPLKTGVARLVSdvltrn-----rndpdfE 168 Laccaria bicolo...
XP_822562    286 acdavtkpvgfqvsrridhseMYASVYQTLQsGQCIGIFPEGGSHdrtsLLPLKAGVALFSLgaav----------rgiD 355 Trypanosoma bru...
XP_760992    121 -------------------qsLFHATFQAMKaGGAIALFPEGGSYtipkLASLKMGAAWAALeysrylqlaqqgervqtG 181 Ustilago maydis...
XP_001830157 106 -------------------qrLFDGTFKALAkGNAVALFPEGTSYteprIMQVKDGAAWAALeyykykea-hpeladqpD 165 Coprinopsis cin...
NP_596450    168 rvllspegssykvapeidqtyVYNEVRRRLVkGACIALFPEGGSHdrpeMLPLKAGVAIMALetlsq--------hpdcG 239 fission yeast
Feature 1                                                                        
AAK14816     225 VSIIPVGLSYsklyqLQGCATLFYGnaiiisqdlck----------eynnnnreaisKLLSKIE 278 malaria parasite P. falciparum
XP_001879312 169 LKLVPVAVVYtdkarYRSRILVKYCppihvddyaeelfeetadpdaasrsvvkkimvQVEKQMM 232 Laccaria bicolor S238N-H82
ZP_02925633  174 LQVIPLGVHYeepslFRRRVEVVIGpripleide--------------tmsarqrlvEIRRRMT 223 Verrucomicrobium spinosum DSM 4136
ZP_02959629  164 FNIVPLGLFYampdrFASHAEIYVGkpiqitaqenee---------sdrewekrihtQISQSLD 218 Providencia stuartii ATCC 25827
YP_002759560 200 LTIVPFGVQYeapsrPGSDCCAVIGpgfslrawreak---------cvdgdgsprppSLSAELA 254 Gemmatimonas aurantiaca T-27
XP_001877801 169 VSVLTCSITYmhrqhFRSDVLVSFHtpttftpknnpe---------llapvdfdqirSLTSEMQ 223 Laccaria bicolor S238N-H82
XP_822562    356 VKVVPCGLTYfyghkFRSRAHVEFGepitpsaevvalf------ntdkrkatgifleQLNEELR 413 Trypanosoma brucei TREU927
XP_760992    182 VSILPTAVVYddksvFRSRAMLKFGkplsldgyi---------------deflslpsTVEAEVQ 230 Ustilago maydis 521
XP_001830157 166 VKIVPAAIVYtnkskYRSSVVVEYGkpisaadfkeqflst---eenaprsavkcltrTLESELV 226 Coprinopsis cinerea okayama7#130
NP_596450    240 LQLLPCGMNYfhphrFRSRAVLEFGsplsipteyv------------elykakkrreAIQGVLD 291 fission yeast

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