Conserved Protein Domain Family
BAR_SFC_plant

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cd07606: BAR_SFC_plant 
The Bin/Amphiphysin/Rvs (BAR) domain of the plant protein SCARFACE (SFC)
BAR domains are dimerization, lipid binding and curvature sensing modules found in many different proteins with diverse functions including organelle biogenesis, membrane trafficking or remodeling, and cell division and migration. The plant protein SCARFACE (SFC), also called VAscular Network 3 (VAN3), is a plant ACAP (ArfGAP with Coiled-coil, ANK repeat and PH domain containing protein), an Arf GTPase Activating Protein (GAP) that plays a role in the trafficking of auxin efflux regulators from the plasma membrane to the endosome. It is required for the normal vein patterning in leaves. SCF contains an N-terminal BAR domain, followed by a Pleckstrin Homology (PH) domain, an Arf GAP domain, and C-terminal ankyrin (ANK) repeats. BAR domains form dimers that bind to membranes, induce membrane bending and curvature, and may also be involved in protein-protein interactions.
Statistics
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PSSM-Id: 153290
View PSSM: cd07606
Aligned: 7 rows
Threshold Bit Score: 238.544
Threshold Setting Gi: 159478765
Created: 13-May-2009
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
dimer interface
Feature 1:dimer interface [polypeptide binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                #  ##   # ##  ## ##         ## ##  ## ##  #                #  ##        
NP_196834     14 KQLQSMEESAEILRErSLKFYKGCRKYTEGLgeaydGDIAFASALETFGGGHNDpisvafggpvmtKFTIALREIGTYKE 93  thale cress
XP_001759158  14 KQLHALEESAEALRErCQRFYKGCRKYTDGLgeaydGDIAFANALETFGGGHDDpisvavggpvmtRFTIALREIGTYKE 93  Physcomitrella ...
NP_176283     15 KQVFSLEGTSDELKDrCQKLYKGVKKFMGALgeastGVSAFADSLEEFGAGHDDpvsvsiggpvisKFINTLRELSSYKE 94  thale cress
EEH57301      22 AQINAMEKEVDELRDkTLKLAKDCGKYRDGLedayaRELNFSESLKGFYGSLEDafacevggavieRFTTAVQEIADARA 101 Micromonas pusi...
ACO68116      19 ARLRELEQDADVLRDrSSRLTRDCRAYRDALedayaSEVNFQESVRSLYGSIDDafgnavgasvleRLLSAMSECAAARC 98  Micromonas sp. ...
CAN78714      14 KQIQCLEESAESLRErSLKFYKGCRKYTEGLgegydGDIAFASALETFGGGHNDpisvafggpvmtKFTIALREIGTYKE 93  wine grape
XP_001697471  11 LKVAEMEGSCRKLKDkVSKLVAHYRQYRDALvhlckAQSLFVGGLAEFFSGEESeqlsg--gvpvhKYISTLGESTSYFD 88  Chlamydomonas r...
Feature 1                                                                                        
NP_196834     94 VLRSQVEHILNDRLLQFAn-mDLHEVKEARKRFDKASLTYDQAREKFLSlrkgtksdvaaalEQELHTSRSMFEQARFNL 172 thale cress
XP_001759158  94 VLRSQVEHMLNDRLTQFVs-tDLQDVKELRKRFDKASLHYDQVREKFLSlkkdakpeivvgfEEDLRNAKSQFEQTRFNL 172 Physcomitrella ...
NP_176283     95 FLRSQVEHVLLERLTNFMt-vDLQEAKESRRRFDKAVHSYDQAREKFVSlkkntrgdivaelEEDLENSKSAFEKSRFNL 173 thale cress
EEH57301     102 ALLTHVERDLCGALHRLAt-tELDDARDARKRFDKALNNYERSRARFMSltrdakpeslkaaEEDVKATRRAFETDRFHL 180 Micromonas pusi...
ACO68116      99 DLMSEVETELIDPLAKIAdgpVCQEVADARRRFDRTNADHERARAKFLAltkdakeehlraaEDELASTRHEFETARFDL 178 Micromonas sp. ...
CAN78714      94 VLRSQVEHMLNDRLIQFVn-iDLHDVKEARKRFDKASLLYDQVHSTFLLf------------RNFVVTVNVILLHSRTTL 160 wine grape
XP_001697471  89 LLKIQIEFAADQISAEWLd-dLLVGARDSHRAFERSSSDLEDATSRVLA-------------LKKAGRPGEGRSGARFDV 154 Chlamydomonas r...
Feature 1            #  ## #     #  ## ##    ##  ## ##           ## ##  
NP_196834    173 VTALSNVEAKKrf-eFLEAVSGTMDA--HLRYFKQGYEL---------LHQMEPY 215 thale cress
XP_001759158 173 MTALSNIEAKKkf-eFLEAVSGSMDA--HLRYFKQGYEL---------LHQMEPY 215 Physcomitrella patens subsp. patens
NP_176283    174 VNSLMTIEAKKky-eFLESISAIMDS--HFKYFKLGYDL---------LSQLEPY 216 thale cress
EEH57301     181 MAQLHKATSRKkv-eFKRRLAGAMHA--HLRFFDVGHDT---------LRELEPF 223 Micromonas pusilla CCMP1545
ACO68116     179 MGKLQRADAVRrv-vFKRRLARNVES--HRAFFARVHGA---------YEELGAF 221 Micromonas sp. RCC299
CAN78714     161 CNVSHYCNGINfvcgHIEYLSWAFMRfeAILFLKINLEKsesinveelARDMGCR 215 wine grape
XP_001697471 155 ARRLAAADARRry-sFLQLLLDSVGA--HHAALRSGSEM---------LGRLTPL 197 Chlamydomonas reinhardtii

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