Conserved Protein Domain Family
ALDH_BenzADH

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cd07152: ALDH_BenzADH 
NAD-dependent benzaldehyde dehydrogenase II-like
NAD-dependent, benzaldehyde dehydrogenase II (XylC, BenzADH, EC=1.2.1.28) is involved in the oxidation of benzyl alcohol to benzoate. In Acinetobacter calcoaceticus, this process is carried out by the chromosomally encoded, benzyl alcohol dehydrogenase (xylB) and benzaldehyde dehydrogenase II (xylC) enzymes; whereas in Pseudomonas putida they are encoded by TOL plasmids.
Statistics
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PSSM-Id: 143470
View PSSM: cd07152
Aligned: 20 rows
Threshold Bit Score: 625.858
Threshold Setting Gi: 118468011
Created: 2-Jan-2009
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Feature 1:catalytic residues [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                        
P43503        35 GDILGITGvangeDVDAAVNAAKRAQKEWAAiPFSERAAIVRKAAEKLKEREYEFADWNVRECGAIrPKGLWEAGIAYEQ 114 Pseudomonas putida
YP_709334     35 GDILGITGvangeDVDAAVNAAKRAQKEWAAiPFSERAAIVRKAAEKLKEREHEFADWNVRECGAIrPKGLWEAGIAYEQ 114 Pseudomonas putida
YP_551303     39 GGTLGQIGiastaDVDRAARSAQSARAAWAAtPFDQRAAVMREAARLLKERAGEINGWNVRECGSImPKAEWELSATYEQ 118 Polaromonas sp....
YP_702947     35 GAVLGEIGaadasDIDRAARRAAAAQPDWAArTGHARADVLRKAAMTLDANRAEVERWLIREGGAVpGKAAFEVDLVLSE 114 Rhodococcus sp....
YP_369152     39 GKRLGAIGiassqDVAKAAAIAREAQKAWANvPGPKRGDVLREFSWLVLVHANEIADQIVRETGSIrAKALWEVQVSARE 118 Burkholderia sp...
AAY98503      34 GATLGSVGladegDLERAVDRAVAAQRDWAArPHTERAAVLRRAGDLWQRHADEIERWIMRESGSLrPKAQLETHVAAQE 113 Rhodococcus aet...
CAJ89676      33 GERLGAVGlvtpeDVGRAAARAAEAQREWAAtPPQRRAAVLRRAGELFTEHAEEIEEWLVREAGSVrSKAGFEARLAIGE 112 Streptomyces am...
YP_001339377  35 GKVLSEVGiatadEVYLACQRANEAQKEWLKvPPRDKATLFHKAAAFMQENFDELALYIARETGGIiPKGQHEVKEAILI 114 Marinomonas sp....
NP_792747     40 SELLMNTAmagaaDIAIACREAALAQPAWAAmGPREKAEIFLMAADHAVCAFDELALYVARETGGSlHKGQHEVNETIVL 119 Pseudomonas syr...
NP_635749     52 GGLLHEVGkadlsDVEAAIAQAKHAQRAWAItSPRERAAVFHRAAQLMEAHRAEATLLIARETGGImPKAEREVSEAIAY 131 Xanthomonas cam...
Feature 1                                                   #                                    
P43503       115 MHQAAGLASlp--nGTLFPSavpGRMNLCQRVPVGVVGVIAPWNFPLFLAMRSVAPALALGNAVILKPDLQTAVTGGALI 192 Pseudomonas putida
YP_709334    115 MHQAAGLAYls--nGTLFPSavpGRMNLCQRVPVGVVGVIAPWNFPLFLAMRSVAPALALGNAVILKPDLQTAVTGGALI 192 Pseudomonas putida
YP_551303    119 MLMAAALPMqa--nGQMFPStmpGRTNLWRRVPIGTVGVIAPWNFPLLLAMRSVAPALALGNAVLLKPDAQSAVTGGMLI 196 Polaromonas sp....
YP_702947    115 LWEASALPTqp--wGHLLPTsqeGRVSIGRRVPLGVVGVISPWNFPLVLAMRAVAPALALGNAVVLKPDVQTAISGGVVI 192 Rhodococcus sp....
YP_369152    119 VLEAAALGSqp--eGVLVATaeaGRQSIARRIPVGVIGVITPWNSPFILGSRAIGPALAMGNAVILKPDVQTPIAGGVTF 196 Burkholderia sp...
AAY98503     114 CFEGAALPSha--lGEILPSe-aPRLSMSKRVPVGVVGVIAPFNFPLILAIRSVAPALALGNAVILKPDPRTAVCGGVAL 190 Rhodococcus aet...
CAJ89676     113 CFECAGLPThp--qGEVLTSe-eARWSLTRRRPAGVVSVIAPFNFPLILGLRSVAPALALGNAVLLKPDPRTAVSGGVVI 189 Streptomyces am...
YP_001339377 115 LQLAANMTLep--nGLTLPSv-pEKMSYATRKAIGVVGVISPFNFPMILSIRSIAPALATGNAVVTKPDPQTPVTGGFIL 191 Marinomonas sp....
NP_792747    120 LRQAAGMLSqahghGVILPSa-aGRLSYARRVAHGVVGVISPFNFPLVLSLRSVAPALAAGNAVVLKPDPQTPISGGFLI 198 Pseudomonas syr...
NP_635749    132 YQQAAGLPLqa--mGQVLPTa-aGQLSLARHLPLGIIAVISPFNFPLILSLRSVAPALAMGNAVILKPDPRTPYTGGVII 208 Xanthomonas cam...
Feature 1                                                                     #                  
P43503       193 AEIFSDaGMPDGVLHVLPGGAdVGESMVANSgINMISFTGSTQVGRLIGEKCGrMLKKVALELGGNNVHIVLPDADLEGA 272 Pseudomonas putida
YP_709334    193 AEIFSDaGMPDGVLHVLPGGAdVGESMVANSgINMISFTGSTQVGRLIGEKCGrMLKKVALELGGNNVHIVLPDADLDGA 272 Pseudomonas putida
YP_551303    197 AQVFADaDLPAGVLHVLPGGPaTGDAVVRHPaVNMISFTGSTAVGRQIGEVCGgLLKKVALELGGNNAIVVLDDADLDAA 276 Polaromonas sp....
YP_702947    193 AQLFAAaGLPEGVLHVLAGDAePGQALSEHPaVSLISFTGSTSVGRQVGATAGrTLKRVSLELGGNNALIVLDDADLDAA 272 Rhodococcus sp....
YP_369152    197 ARLFEEaGLPAGLFHVLPGGAdTGSALVNEPlVDMISFTGSTRVGRQIGSIAGgQLKRVSLELGGNNPYIVLEDADIEAA 276 Burkholderia sp...
AAY98503     191 ARIFEQaGLPAGVLSVLPAGAdVGAALVDDPrVPVISFTGSTPAGRAVGAAASrNLKKVHLELGGNSAIVVLDDADLAAT 270 Rhodococcus aet...
CAJ89676     190 ARIFEEaGLPAGVLHLLPGDGaVGEALVEAPeVRVISFTGSTPVGRIIGEQAGrLLKRAHLELGGNNALVVLPGADVAKA 269 Streptomyces am...
YP_001339377 192 ALALEAaGLPKGVFQVLPGAVeAGEALCAAPeIGMVAFTGSTAAGRKVGEACGrNLKKVSLELGGKSSLIILEDADLDVA 271 Marinomonas sp....
NP_792747    199 ARLFEEaGLPKGLLHVLPGAAdAGEALCRDTnVQMITFTGSTGAGRKVAEAAGrNLKKVSLELGGKNPLVILEDADLDLA 278 Pseudomonas syr...
NP_635749    209 AQVLEEaGLPKGLLHVLHGGAdIGQALVEAPdVPMIAFTGSTAAGRRIGELAGrHLKKVALELGGNNAVIVLDDADLERA 288 Xanthomonas cam...
Feature 1                    #  #                                                                
P43503       273 VSCAAWGTFLHQGQVCMAAGRHLVHrdVAQQYAEKLALRAKNLvVGDPNSDqVHLGPLINEKQVVRVHALVESAQrAGAQ 352 Pseudomonas putida
YP_709334    273 VSCAAWGTFLHQGQVCMAAGRHLVHrdVAQQYAEKLALRAKNLvVGDPNSDrVHLGPLINDKQVVRVHALVESAQsAGAK 352 Pseudomonas putida
YP_551303    277 SSCGAWGAFLHQGQICMQAGRHLVHrsVAEAYSQRLKQRAEALhVGNPHAGpAHLGPVINAKQRDRIDQIVQASVaQGAR 356 Polaromonas sp....
YP_702947    273 SSAGAWGSFLHQGQVCMTAGRHIVLesVADRYLEKLTARAANLpVGDPNTGqVALGPLINEHQVANVDRIVRATRdAGAE 352 Rhodococcus sp....
YP_369152    277 ASAGAWGAFFHQGQICLTAGRHLVHerVAEAYAAALVRKARALvVGDPFDDrVQIGPIINERQAANVDRIVAETRdQGAT 356 Burkholderia sp...
AAY98503     271 VAAGAAGSFLHQGQVCMTTGRHIVHesVYDEYVAQLAAKAEALpVGDPATEqVALGPIIDHGQLEKIHALVTASVdAGAR 350 Rhodococcus aet...
CAJ89676     270 ASAGAFGSYLHQGQICMTTGRHIVHesLVEEYTAALAAKADSLpVGDPARQdVALGPIIDRRQLERVHGIVEASVaAGAK 349 Streptomyces am...
YP_001339377 272 ASNIAWGAYFHQGQICMASGRILVQesIAEVLTAKIVEKAKHLpVGDPASGkVALGPLINQRQLEKVHAIVQDTIaAGAK 351 Marinomonas sp....
NP_792747    279 ASNAAFGAWLHQGQICMATGLILVHesIVAAFTRKLADKARALtVGNAARGqAALGPLINQRQLQHVHQVVSDSLqAGAQ 358 Pseudomonas syr...
NP_635749    289 ASAIAFGAYLHQGQICMATGRVLVQrgVADALTKLLADKARHLpVGDPVSGtVALGPIIGQRQLQRVLDIVDDSIdAGAV 368 Xanthomonas cam...
Feature 1                                                                                        
P43503       353 VLAGGTYqDRYYQATVIMDVKpeMEVFKSEIFGPVAPITVFDsIEEAIELANCSEYGLAASIHTRaLATGLDIAKRLNTG 432 Pseudomonas putida
YP_709334    353 VLAGGTYqDRYYQATVIMDVKpeMEVFKSEIFGPVAPITVFDsIEEAIELANCSEYGLAASIHTRaLATGLDIAKRLNTG 432 Pseudomonas putida
YP_551303    357 VVTGGTYeGLLYRPTVLTEVQpeMPAFTDEIFGPVAPITVFDtDEEAAALVNASAYGLAAAIHSSnISRAMALANRLHTG 436 Polaromonas sp....
YP_702947    353 IRTGGTFdGLFYRPTVLAGVTpaMPAFQEEIFGPVAPVVVVKdEAEAIAVANDTEYGLVAAIQTGsVERGERLADQLRTG 432 Rhodococcus sp....
YP_369152    357 VLAGGTRnGLFFEPTVIVGVRpgMAAFDEEIFGPVAPITTFSsDDEAVALANGTDYGLVAAVASAdLAHAQRIADRLHSG 436 Burkholderia sp...
AAY98503     351 LVAGGTYkGLFYRPTVLADVPagAPAYAREVFGPVAPVVKFStLDEAVALATDTEYGLSLGIFTRdVGKGLALAERIPTG 430 Rhodococcus aet...
CAJ89676     350 VAAGGEIdGACYRATVLTGVTtrMPAWREEIFGPVAPVISFStPEEAARIVNDCEYGLSVGILGD-VGTAMKLADRIDSG 428 Streptomyces am...
YP_001339377 352 LEAGGTHeGPFYAPTVLSNVKpgMRSFDEEIFGPVVNIVTFKhDDEAVTMANNTQYGLAGAVISNdLSRAQNIGAQLHVG 431 Marinomonas sp....
NP_792747    359 LETGGEYeGLFYRPTVLSGVKpgMRAFEEEIFGPVAVVVSFSsDEQAIELANRSEYGLAAAVISPdVGRATALGDRLRCG 438 Pseudomonas syr...
NP_635749    369 VEAGATHdGLFYAATVLSNVRpgMRVFDEEVFGPVINITVFDtDEEAAVLANHGEYGLVAGIMSAsVSRAMVLGEQLHTG 448 Xanthomonas cam...
Feature 1                                                       
P43503       433 MVHINDQpINCEPHVPFGGMGASGsGGRFGG-PASIEEFTQSQWISM 478 Pseudomonas putida
YP_709334    433 MVHINDQpINCEPHVPFGGMGASGsGGRFGG-PASIEEFTQSQWISM 478 Pseudomonas putida
YP_551303    437 MIHINDQtVNNEFHVPFGGMGASGnGGRFGG-PANLEEFTQSQWVSV 482 Polaromonas sp. JS666
YP_702947    433 MVHINDQtLNNDAYAPFGGTGASGnGTRFGT-QSSWDEFTQWQWRTS 478 Rhodococcus sp. RHA1
YP_369152    437 VIHINDQtVLHEVYGPIGGVGASGnGFNHST-LTNADQFSEWQWITT 482 Burkholderia sp. 383
AAY98503     431 IAHINDQtVGDEANIPFGGLGASGnGARFGGaANSIEAFTESRWITV 477 Rhodococcus aetherivorans
CAJ89676     429 KVHINEQtVSDEPHAPFGGVKASGtGSRFGGaTANVEAFTETQWVTV 475 Streptomyces ambofaciens ATCC 23877
YP_001339377 432 LLHINDQtVNDECINPFGGCGASGnGSAVCG-PADWDLYTHWQWVTV 477 Marinomonas sp. MWYL1
NP_792747    439 MLHINDQtVADECINSFGGRGASGnGSSAGS-PSDWDEYSQWQWVTV 484 Pseudomonas syringae pv. tomato str. DC3000
NP_635749    449 LLHINDQtVADEVINPFGGTGASGnGTSVGG-PADWEQYMHWQWLTI 494 Xanthomonas campestris pv. campestris str. ATCC ...

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