Conserved Protein Domain Family
NTP_transferase_like_2

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cd06426: NTP_transferase_like_2 
NTP_trnasferase_like_2 is a member of the nucleotidyl transferase family.
This is a subfamily of nucleotidyl transferases. Nucleotidyl transferases transfer nucleotides onto phosphosugars. The activated sugars are precursors for synthesis of lipopolysaccharide, glycolipids and polysaccharides. Other subfamilies of nucleotidyl transferases include Alpha-D-Glucose-1-Phosphate Cytidylyltransferase, Mannose-1-phosphate guanyltransferase, and Glucose-1-phosphate thymidylyltransferase.
Statistics
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PSSM-Id: 133048
View PSSM: cd06426
Aligned: 34 rows
Threshold Bit Score: 279.782
Threshold Setting Gi: 125975125
Created: 7-Nov-2008
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Substratemetal binding
Feature 1:Substrate binding site
Evidence:
  • Comment:Putative substrate binding site based on conserved residues of similar proteins.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1           ###                                           #                              
YP_444750    122 VVLMAGGLGTRLRPLTDdcPKPLLEVGDKPILETILEGFIahGFHRFYLSVNYKAGMIEDYFRDGsnwGVDISYVHEEKR 201 Salinibacter ru...
EDK34479     124 VVIMAGGKGTRLHPYTKiiPKALIPIGEIPIIERIINRFLefKFENFYITVNYKKEIIKAYFSKKl--SYKISFLEEKKP 201 Clostridium klu...
YP_001039035 121 VVIMAGGLGTRLYPYTKilPKPLIPIGEIPIAEHIMNRFNkfGCRQFYLILNHKKNTVKAYFNDIe-kNYSVNYVEEEKP 199 Clostridium the...
NP_896545    129 IVIMAGGKGKRLMPLTAntPKPMLPVHGKPMLEHILDRLRedGFKNVIISVNYLSERITSYFQDGskfDMNISYLYEDKP 208 Synechococcus s...
YP_429618    128 VVIMAGGKGTRLDPFTKilPKPMLPLGDKPIVEVLMDRFYdqGFSQFILSVGYKAEVVKLYFNDSngrPYKVNFVQEEEP 207 Moorella thermo...
NP_282475    119 IIIMAGGLGSRLKELTKdtPKPMLKVGKKPILESIIQRLKnqNFENFIFCVNYKKQIIEDYFQKGqkfGVKISYIKERKK 198 Campylobacter j...
YP_001091629 128 FFILAGGKGLRMRPLTKnlPKPMLHISGKPMIELIINNAKefGFRNFVLSIGYLGEVIKEYFGNGdkfGINISYIQEEKP 207 Prochlorococcus...
YP_877860    122 VFILAGGLGTRLRPLTEkvPKPMLKIGDKPMLERIIKQFKayGFRNFIISINYKGEIIENYFKDGsdfDVNIEYVREEKK 201 Clostridium nov...
YP_098721    126 IVIMAGGQGTRLKPLTNiiPKPLIPIGEKTFMEDIMDRFVkcGSNNFYVSVNYKADVIKHYFSTLrdsSYRINYFQENVP 205 Bacteroides fra...
ZP_01961456  131 VVIMAGGKGTRLKPITNviPKPLVPVGDKTILEVIMDQFEgiGCHKFYMSVNYKADMMEYYLSQLd-hKYDIEFFMEDKP 209 Bacteroides cac...
Feature 1                              # #                                                       
YP_444750    202 LGTAGPLSLLperp-detMIVMNGDLLTKLNFTHLLDFHREHGAVATMCVREHETQVPYGVIEtdd-qsmEGIEEKPTer 279 Salinibacter ru...
EDK34479     202 LGTAGGLSLVgnsi-gntFFVSNCDILVNANYSKILEYHKEHNNKVTVVTALKNYIIPYGILNlnqkgdiASIDEKPNye 280 Clostridium klu...
YP_001039035 200 LGTGGGLSLLkgki-tstFVLSNCDILIEEDYEKIYSYHKKMNNLITMVCSLKNIKIPYGVVEindkgeiENIKEKPElv 278 Clostridium the...
NP_896545    209 LGTAGALSGLdsktrenpVIVTNADILSGISYSDLLIYFRRNTSNGLMAVRTQEWQNPFGVVQsng-shiTNIIEKPThy 287 Synechococcus s...
YP_429618    208 LGTAGALGLLrqql-qgtFLVTNCDVIIEMNYGELLRYHHEKGNALTIVGALRDFTIPYGVLRtea-gefHQIEEKPSfh 285 Moorella thermo...
NP_282475    199 LGTAGALSLIkqef-kesFIVMNADILTELDFNALLKAHKKSKALMSVCVREFEQQIPYGVITqkq-gfiENIEEKPTqk 276 Campylobacter j...
YP_001091629 208 LGTAGSLAYLkkdlltdyVFITNGDVVTSLEYSNMLNFAKYTKADGVIAVKEFGLQNPFGVIEtsn-dnfIGISEKPIyk 286 Prochlorococcus...
YP_877860    202 LGTAGSISLAkdkl-kddFIVINGDILTGIDFEELLNYHKENKYDITAGARNYEMRVPYGVMVmkd-kliKSLEEKPTyn 279 Clostridium nov...
YP_098721    206 LGTAGSLTLMrdki-httFFVSNCDIIINEDYSQILKYHKENKNELTVVAALKNYPIAYGVLYtkengllDSIVEKPDlt 284 Bacteroides fra...
ZP_01961456  210 LGTIGSVSLLkgki-ttpFFVSNCDSINEQDYRDVYDYHTNNHNDMTIVTMVKSFKIPYGVIEtgedglmVNLKEKPEht 288 Bacteroides cac...
Feature 1                                                                       
YP_444750    280 YFVNAGIYVLEPETLGYVPenefFDMPDLFKRLIDEGkeATVFPVr-EYWQDVGRkEDFHRVN 341 Salinibacter ruber DSM 13855
EDK34479     281 FLINTGMYVLEVDVLRYISkgiyFNMTDLINICLSNGekVGIYPVtdNDWLDMGEfREMKSMI 343 Clostridium kluyveri DSM 555
YP_001039035 279 YFVNTGLYFAEPKIIEELEenrpVEFPDIIKKYKSRGekIGVYPIseNSWMDMGQfDEMEKMK 341 Clostridium thermocellum ATCC 27405
NP_896545    288 YQVNAGLYVLDNKLLDLLTpnsyCDMPDLFRMGLEINlnLQVYPLh-EQWLDIGRpKDYDIAN 349 Synechococcus sp. WH 8102
YP_429618    286 FLVNIGLYVLEPEVLEGLDnssfIHMTDLIMATKDKGlrVGVYPHh-GRWFDIGQwDEYRQTL 347 Moorella thermoacetica ATCC 39073
NP_282475    277 FLVSAGIYVLENEILNLIAkneyLDMPELIKLVLQKGk-VNTYIIn-DYWIDIGRpDEFLKAN 337 Campylobacter jejuni subsp. jeju...
YP_001091629 287 STINAGVYVVSKNLIGLIEkgkhIDMNQLFELGINKKkiLKVFALh-EEWTDVGRpEDYKRIR 348 Prochlorococcus marinus str. MIT...
YP_877860    280 FYINSGIYVLSKDVVKYIPdnkeYNMTDLIEDIINDNgrCGAYNIt-EYWSDIGHiEDYKKAN 341 Clostridium novyi NT
YP_098721    285 FKINTGLYILEPNLLDEIPegqfYHITSLIDKLRKENrrIGVFPVseKSWIDVGNwNEYFSII 347 Bacteroides fragilis YCH46
ZP_01961456  289 YMVNSGVYILNPELIDEIPegefFHITHLMEKVKACGgrVGCFPVseDSWKDMGEwPEYLKMI 351 Bacteroides caccae ATCC 43185

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