1XDY


Conserved Protein Domain Family
YedY_like_Moco

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cd02107: YedY_like_Moco 
Click on image for an interactive view with Cn3D
YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been proposed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY, which is likely membrane-anchored by a heme-containing trans-membrane subunit YedZ. Preliminary results indicate that YedY may represent a new type of membrane-associated bacterial reductase. Common features of all known members of this family are that they contain one single pterin cofactor and part of the coordination of the metal (Mo) is a cysteine ligand of the protein and that they catalyze the transfer of an oxygen to or from a lone pair of electrons on the substrate.
Statistics
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PSSM-Id: 239025
Aligned: 8 rows
Threshold Bit Score: 416.468
Created: 13-Jan-2005
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
 
Moco bindingmetal
Conserved site includes 13 residues -Click on image for an interactive view with Cn3D
Feature 1:Moco binding site
Evidence:
  • Structure:1XDY; E.coli YedY with bound molybdenum cofactor

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1          #####                                                     #                  
1XDY_J       41 SGYNNFYEFGLDKadpAANAGSLKTDPWTLKISGEVAKPLTLDHDDLTRrFPLEERIYRMRCVEAWSMVVPWIGFPLHKL 120 Escherichia coli
NP_953768    84 AMYCNFYEFTSGKd-vWRYVDQFITRPWQISVTGLVKNPKVFDVDELVRtMPLEERTYRHRCVEAWAMAVPWVGFPLAEL 162 Geobacter sulfur...
Q9PIC3       56 TNYVNFYEFSTDKrkaVSLAQNFNTQNWKIDISGEIEKPLTLSMEDILK-FPLEERIYRFRCVETWSMVVPWVGFELRRL 134 Campylobacter je...
P58770       68 TSYNNFYEFGVGKsdpKENSGKFKPTPWTVKVDGLVSKPQEFGIEELMK-YPLEERTYRMRCVEGWSMVIPWIGFPLSAL 146 Agrobacterium tu...
Q9RRF6       90 TTYNNFYELGLGKddpARHAGALPTRPWTVVVDGEVKKPVTLDIDTLQSwFPLEDRIYRMRCVEGWSMVMPWFGFPLAAL 169 Deinococcus radi...
ZP_00174476  89 GQYNNFYEFGGTKk-iWLNAQNLPTENWKVEVTGLVKNPKTYDIDDLKKtFPLEERIYRFRCVEAWSMVLPWVGFPMKAL 167 Crocosphaera wat...
Q8XV50       83 TTYNNFYEFGTDKsdpARYAGTLRPHPWQVSVEGLVKAPKTYDLDDLMKmAPMEERIYRLRCVEGWSMVIPWVGFPLAEL 162 Ralstonia solana...
NP_907870    69 SGYVNFYEFSTSKtapVGLSKTLRPYPWELLASGEVENPQSLSIDELYQ-FPLEERIYRFRCVEGWSMVVPWIGFPLSAL 147 Wolinella succin...
Feature 1                       #                      #                            #    #      
1XDY_J      121 LALAEPTSNAKYVAFETIYAPEQMPGQQDRfiggGLKYPYVEGLRLDEAMHPLTLMTVGVYGKALPPQNGAPVRLIVPWK 200 Escherichia coli
NP_953768   163 VKRADPLPGATHLRFLSFLRKDQAPNQSGLf--sTDLWPYHEGLTLAEATNELAFLAVGVYGRELPKQHGAPIRLVLPWK 240 Geobacter sulfur...
Q9PIC3      135 IEMAKPTSEAKFVKFTTLLDKSQFPDQDALf--pTIDYPYVEGLRMDEAMHPLTLLAVGMYKKALKPQNGAPIRLVVPWK 212 Campylobacter je...
P58770      147 LDKVEPLGSAKYVSFETVVRPEEMPGQSGLf--qPLSWPYVEGLRLDEARHPLTILAVGLYGETLPNQNGAPIRLVVPWK 224 Agrobacterium tu...
Q9RRF6      170 LRRLEPTGAARYVQFTAINAPDKLPGQRPW----VLEWPYTEGLRLDEALHPLTLLAVGLEGRSLPAQNGAPLRLVVPWK 245 Deinococcus radi...
ZP_00174476 168 MAAVEPKSEAKYVRLTSFYDKEITTGPSFHl--gALPWPYKEGLRIEEMANELAFFAVGIYGEDLPKQHGAPIRMVIPWK 245 Crocosphaera wat...
Q8XV50      163 IRRVEPQGSARYIQFISLADKRQMPGVSSP----VLDWPYSEGLRMDEAMHPLVLLTFGLYGQVLPNQNGAPVRVIVPWK 238 Ralstonia solana...
NP_907870   148 LERLKPTTKARYVKFTTLLDPTQFPDQKRGal-gVIPHPYVEGLRLDEAMHPLTLLAVGMYGEKLPAQNGAPLRLIVPWK 226 Wolinella succin...
Feature 1        #  # #                                                     
1XDY_J      201 YGFKGIKSIVSIKLTRERPPTTWNLAAPDEYGFYANVNPYVDHPRWSQATERFIGSGGIL 260 Escherichia coli
NP_953768   241 YGFKSIKSIVEISFTDRQPSTFWSSLGPDEYGFWANVNPDVDHPRWSQKSERMLGTGERR 300 Geobacter sulfurreducens PCA
Q9PIC3      213 YGFKSIKSIVKIEFTKEQPKSTWESYAPSEYGFYANVNPNVSHPRWSQANERALGDFFTK 272 Campylobacter jejuni
P58770      225 YGFKGIKSIMRISLVEKQPETTWKNSNAREYGFYSNVNPHVDHPRWSQATEQRIGEGGFF 284 Agrobacterium tumefaciens str. C58
Q9RRF6      246 YGFKGIKAIVRMTLTRTQPQTTWALAAPDEYGFYANVNPAVPHPRWSQATEQRIGESGRR 305 Deinococcus radiodurans
ZP_00174476 246 YGFKGAKSIVKIEFLKEQPATYWNTIDPNEYDFEANVNPSKPHPRWSQATEKFISTGPGL 305 Crocosphaera watsonii WH 8501
Q8XV50      239 YGFKSAKSIVRIRFVDKQPPTSWNIAAPNEYGFYSNVNPSVDHPRWSQATERRIGEDKGG 298 Ralstonia solanacearum
NP_907870   227 YGFKSIKSIAKIELTQEEPLNTWKLLNPREYGFYANVNPEVDHPRWSQASERLLGSLLKQ 286 Wolinella succinogenes DSM 1740

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