Conserved Protein Domain Family
cas1_MYXAN

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TIGR03983: cas1_MYXAN 
CRISPR-associated endonuclease Cas1, subtype MYXAN
Members of this protein are the Cas1 endonuclease, or Cas1 domain in Cas4/Cas1 fusion proteins, of the MYXAN subtype of CRISPR/Cas systems. These systems typically feature repeats and spacers each about 36 base pairs in length. Species with this type of CRISPR system include Myxococcus xanthus, Cyanothece sp., Leptospira interrogans, Sorangium cellulosum, Anabaena variabilis ATCC 29413, etc.
Statistics
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PSSM-Id: 274899
Aligned: 6 rows
Threshold Bit Score: 560.152
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
REF_chgcsh:AE010300_702 201 PIRLFPEKREKTTLHVFGHDSRIKKSDNVLlveKVTETgeKS--KSEKIPIQEIESVNIHGNCQISSQMIKFLVSEEIPV 278 Lept...
WP_012307389            206 PIRLFPKDDDRQILHTLEPGTRVGRTGEQI---KITRR--DQ--PIEKIAVQQVSQVVLHGFSQISTQALHFLASHNVGI 278 Syne...
WP_009544027            212 PVRLFPQDDEREVIHVLEPGTRIGRTGEQL---KISRR--NE--ADEKVSIQQVSQVVLHSFSQISTQALHFLSYKDVGI 284 Cyan...
WP_012599593            212 PVRLFPVDDEREVIHVLEPGTRVGRTGEQL---KISRP--NQ--PDEKIAIGQVSQVVLHSFSQISTQAVHFLAYKEVGI 284 Cyan...
WP_012241784             19 PVRLYPPDTERRSLHVVSHGARIGRASDAF---EVTER--EG--ERTRIGAREVSDIVVHGHAQITTQALRLCAAEEIAV 91  Sora...
WP_011557179            220 rpRLFPEDDVRQVLHVATPGTRVGRAAEEL---VVTPP--EGegAPSRQPGRMVSALIAHGAVQVSAQALAYCVENDIGV 294 Myxo...
REF_chgcsh:AE010300_702 279 HWFSGGGNYIGGININPSGVQRRIRQFKALTKETIRLNLAKKLVSAKCESQLRYLLRATRGKDETRNETESYLATIRSGL 358 Lept...
WP_012307389            279 HWISGGDRYIGSFDNRQGSIQRRIQQYRALSQTDFCVDLAKKLVWCRGQGQRKFLMRGKRSNKASSPKLNEAISQMKRVL 358 Syne...
WP_009544027            285 HFVSGGGRYVGSLDTRNGSIQRRIRQYEALTKSDFCLELARKLVKCRGEGQRKFLMRGKRNIKRKSPDLEKAIAQMKAVL 364 Cyan...
WP_012599593            285 HFVSGGGRYIGSIDARSRSIQRRVRQYQALSQPDFCLELARKLVACRGEGQRKFLMRGKRNKKGDSLALEKTIAQMKAVL 364 Cyan...
WP_012241784             92 HFVGAGGAHVGVFSGGSSGVQRRIRQFRGLTDDVFAIGLARRLVMAKIEMQLRHVLRASRKDEALRAGLDEPIESLRGGL 171 Sora...
WP_011557179            295 HWFTSGGRYLGGLGGGAGNVHRRLRQFEALRQASVCLGLARRLVAAKLEGQLRFLLRASRGDSESRQVLASAVRDLRALL 374 Myxo...
REF_chgcsh:AE010300_702 359 KNIESADSPSQLLGIEGSSARAYFSGLPALL-KNSDPFLVPNGRSKRPPKDPFNATLSFLYSLLYKSVRQAIIAVGLDPS 437 Lept...
WP_012307389            359 KQVENAENLATLLGIEGNLAALYFGALPCTLtATVPNELRFSGRNRRPPKDRFNALLSFGYSLLLKDVMNSIIAVGLEPA 438 Syne...
WP_009544027            365 KQVPQVESLESLLGFEGNLAALYFGALPNILgKDVSDSLGFAGRNRRPPKDRFNAMLSFGYSLLIKDVMNAILTVGLEPA 444 Cyan...
WP_012599593            365 KQVPQIQSLDSLLGIEGNLAALYFGALSNLLaENAPESLLFSGRNRRPPKDRFNALLSFGYSLLIKDVMNAILAVGLEPA 444 Cyan...
WP_012241784            172 RRAAKAADRTSLMGQEGNAARGYFGALAALVhPDAGDALRPRGRSRRPPEDRFNALLSFGYTLLYRDVLSAILRVGLEPG 251 Sora...
WP_011557179            375 PKCEEAPSLEVLLGLEGAGAARYFGALPYLQgEDVDTRLRFEGRNRRPPRDRFNAVLGFLFGLVHREVEAAIRAVGLDVA 454 Myxo...
REF_chgcsh:AE010300_702 438 FGFYHTPRSSAEPLVLDLMELFRVSLCDMTLIGSINRKSW-IDEDFEITKNKVWLSESGRKKATQLYETRLDDTWKHPVV 516 Lept...
WP_012307389            439 LGFYHQPRTQASPLALDLMEIFRVPLVDMVVIASINRSQWdITEDFSIRGQQVWLSDSGRKKFIECYERRKAELWKHPML 518 Syne...
WP_009544027            445 LGFYHQPRTQAPPLALDLMEIFRVPLVDMIVVTSINRQQWdTETDFDVRGQQVWLSDSGRRKFINLYEQRKAESWKHPVT 524 Cyan...
WP_012599593            445 LGFYHQPRTQAPPLALDLMEIFRVPLVDMPVVTSINRSQWdIQADFDVRGQQVWLSDSGRRKFINLYEQRKAETWKHPVT 524 Cyan...
WP_012241784            252 FGVLHQPRSAAFPLALDLTELFRVPVVDMAVLGAVNRRTFdAERDFVITGRQVWLSDAGHRAFIEVYERRKHEEYRHDVL 331 Sora...
WP_011557179            455 FGFYHQPRGTAGPLGLDVMELFRVPLADMPLVASVNRRAWdADADFEVTSEHVWLSKAGRAKAIELYERRKRETWKNNVL 534 Myxo...
REF_chgcsh:AE010300_702 517 NYSLSYYRMIELEVRLLEKEWSGEANIFAQARLR 550 Leptospira interrogans serovar Lai str. 56601
WP_012307389            519 GYSLSYARLIELEVRLLEKEWSGEAGLFGQLIVR 552 Synechococcus sp. PCC 7002
WP_009544027            525 GYSLTYRRLLELEVRLLEKEWCGEGGLFGQLIVR 558 Cyanothece
WP_012599593            525 GYSLTYRRLLELEVRLLEKEWSGEGGLFGQLIVR 558 Cyanothece sp. PCC 7424
WP_012241784            332 GFSLSYARMMELEARLLEKEWSGEPGLFARFRIR 365 Sorangium cellulosum
WP_011557179            535 GYSLSYARLVELEVRLLEKEWTGKPGLFATFRLR 568 Myxococcus xanthus
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