1XS1


Conserved Protein Domain Family
dCTP_deam

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TIGR02274: dCTP_deam 
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deoxycytidine triphosphate deaminase
Members of this family include the Escherichia coli monofunctional deoxycytidine triphosphate deaminase (dCTP deaminase) and a Methanocaldococcus jannaschii bifunctional dCTP deaminase (3.5.4.13)/dUTP diphosphatase (EC 3.6.1.23), which has the EC number 3.5.4.30 for the overall operation. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism]
Statistics
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PSSM-Id: 274062
Aligned: 15 rows
Threshold Bit Score: 200.234
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1XS1_A   2 RLCDRDIEAWLdegrlSINPRP----PvERINGATVDVRLGNKFRTFRGhtaaFIDLSgpKDEvsaaldrvmsdeivlde 77  Escherichia coli BW2952
O57706   2 LLPDWKIRKEI-----LIEPFS----E-ESLQPAGYDLRVGREAFVSGK----LIDVE--KEG----------------- 48  Pyrococcus horikoshii...
Q9HKK0   2 ILNDSTIMRMVsdgllISENFD----R-GCLTPNGYDLRVD------------AIDVEgrQYS----------------- 47  Thermoplasma acidophi...
Q820X8   2 LLSDVDIQAALedkliQIDPFD----P-QMLQPASLDIRLSRYFRLFNNhtyaYIDPAepQEAltrlv--------evae 68  Tropheryma whipplei s...
O27875   3 ILSDRDIKRYIeegliTIDPLDd--pE-RQIQPSSVDLRIGNEFKGFRVirkpCIDPKdpSDIesymet-------fhve 72  Methanothermobacter t...
Q8TYK5   3 VLSDRDIKRALeegdiVVKPLEeeylE-EALGPASLDLRLGNEFVVFKTlhkpCIDPt--VDAgenter------ivide 73  Methanopyrus kandleri...
Q9KFV3   2 ILSGKTISEKLtekelEITPLT----E-EQIQPASVDLRLGPHFVTIDDskeaVISFErpIRYrewt-----------ts 65  Bacillus halodurans C...
O67539   2 ILSDRSIRELIekgelKVEPYE----P-SHVQCSSLDLRLGNQIALYEGe--gVIDVKkgTKGvril-----------ef 63  Aquifex aeolicus VF5
Q976G3   2 ILGDRDLKYYLekgwiKIDPLR----E-DTVRENGVDLRVGGEIARFIKtd-kVFDPDnpDPAffki-----------ek 64  Sulfolobus tokodaii s...
Q8ZW23   2 ILANDELKKLIstgrlKVDPLY----P-DTIRENGLDLRIGGEYAIYAYeg-vVIKPCelESArhlfr---------vvk 66  Pyrobaculum aerophilu...
1XS1_A  78 gEaFYLHPGELALAVTLESVTL-PADLVGWLDGRSSLARLGLMVHVtaHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIG 156 Escherichia coli BW2952
O57706  49 -K-VVIPPREYALILTLERVKL-PDDVMGDMKIRSSLAREGILGSF--AWVDPGWDGNLTLMLYNASNEPVELKYGERFV 123 Pyrococcus horikoshii...
Q9HKK0  48 -E-FEIGKNVHFLVSTIEILKI-PDDVVGMIWTRSSFARKGIFGSF--GAIDAGYHGNLTLSFFNAGS-AVNLRRGERIA 121 Thermoplasma acidophi...
Q820X8  69 nQaFVLHPGEFILGSTCETVSL-SNDLAARLEGKSSLGRLGLLTHStaGFIDPGFSGQITLELGNVATLPIKLWPGMKIG 147 Tropheryma whipplei s...
O27875  73 dGpFIIHPGEFALATTHEYIAL-PEDLVARVEGRSSIGRLGITMHVtaGYIDPGFHGRITLEISNIGKMPVALYPRQRVC 151 Methanothermobacter t...
Q8TYK5  74 dEeFVINPGELVLAVTHEWIEInAPDITGVLHGRSSLGRLGIQAHVeaGYVDPGWRGRLTLELVNFNPMPVKLRPGMRVV 153 Methanopyrus kandleri...
Q9KFV3  66 dEtIVLPPHTFLLATTMETVKL-PNHLTAFVEGRSSVGRLGLFIQNa-GWVDPGFNGQITLELFNANRLPIELPIGRRIC 143 Bacillus halodurans C...
O67539  64 eEyFDIMPKQFLLATTLEYISL-PPYVTAFVEGRSSLGRLGLFIENa-GWVDAGFEGQITLELFNANDRPIRLYRGMRIC 141 Aquifex aeolicus VF5
Q976G3  65 iEeFIIQPYEHVLLTTEEYIEL-PNDVMAFVNLRSSFARLGLFIPP--TIVDAGFKGQITIEVVGSS-FPVLLRRGTRFI 140 Sulfolobus tokodaii s...
Q8ZW23  67 aDeVVIPPRNFALLTTEEYVKM-PDDVVGFANLRSTLARYGLVIPP--TIVDAGFEGNITIEVVNETPNTIVLRRGMRFL 143 Pyrobaculum aerophilu...
1XS1_A 157 ALSFEPLSGPAVRPYnr-reDAKYRNQQGAVASRI 190 Escherichia coli BW2952
O57706 124 QIVFIRLEDPPRNPY-----SGNYQGSTRLVFSKR 153 Pyrococcus horikoshii OT3
Q9HKK0 122 QIVFVKMIGSAEKPYhi--rSGNYQNSRGIVKDPV 154 Thermoplasma acidophilum DSM 1728
Q820X8 148 QLCFFQLSSPAKNAYgspvcASRYQGQRGPTASLS 182 Tropheryma whipplei str. Twist
O27875 152 QIVFETMTSPAERPYghpsrDSKYIGQTRPQTSRI 186 Methanothermobacter thermautotrophicus str. Delta H
Q8TYK5 154 QIVFHRLSSPAERTYae--ssGKYHGDERPSPSKM 186 Methanopyrus kandleri AV19
Q9KFV3 144 QLVFAEVTG-EVAPYq-----gKYLFQKGATMSEI 172 Bacillus halodurans C-125
O67539 142 QLVFARLDRPPERVYs-----gKYKGQKGVVPSRI 171 Aquifex aeolicus VF5
Q976G3 141 HLIFARTLSPVEHPYq-----gKYQGQKGVTLPKF 170 Sulfolobus tokodaii str. 7
Q8ZW23 144 HLVLAKTEG--RAQYs-----gLYQGQRGVTPPKG 171 Pyrobaculum aerophilum str. IM2
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