2IX0


Conserved Protein Domain Family
RNase_B
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TIGR02062: RNase_B 
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exoribonuclease II
This family consists of exoribonuclease II, the product of the rnb gene, as found in a number of gamma proteobacteria. In Escherichia coli, it is one of eight different exoribonucleases. It is involved in mRNA degradation and tRNA precursor end processing. [Transcription, Degradation of RNA]
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Statistics
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PSSM-Id: 131117
Aligned: 5 rows
Threshold Bit Score: -1
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2IX0_A  23 DDPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFL 102 Escherichia coli
P30850   4 DNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFL 83  Escherichia coli K-12
Q8K9Q5   4 NNPLLAQLKKNLHAKTPRVEGIVKSTERGFGFLEVDAQKSYFIPPKNMKNVMHGDKISAVLKIEKDREIAEPEKLIEPFL 83  Buchnera aphidicola s...
P44440   4 DNPLLAQLKQQIHDSKEQVEGVVKSTDKAYGFLECD-KKTYFIAPPSMKKVMHGDKIKATIEKQGDKEQAEPEALIEPML 82  Haemophilus influenza...
Q9KLE1   4 DNPLLAQLKQKIQETLPKKEGTIKASDKGFGFLEVDSKTSYFVPPPYMKKCMHGDKVVAFIRTENEREVAEPSELIEQSL 83  Vibrio cholerae O1 bi...
P30850   4 DNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFL 83  Escherichia coli K-12
Q8K9Q5   4 NNPLLAQLKKNLHAKTPRVEGIVKSTERGFGFLEVDAQKSYFIPPKNMKNVMHGDKISAVLKIEKDREIAEPEKLIEPFL 83  Buchnera aphidicola s...
P44440   4 DNPLLAQLKQQIHDSKEQVEGVVKSTDKAYGFLECD-KKTYFIAPPSMKKVMHGDKIKATIEKQGDKEQAEPEALIEPML 82  Haemophilus influenza...
Q9KLE1   4 DNPLLAQLKQKIQETLPKKEGTIKASDKGFGFLEVDSKTSYFVPPPYMKKCMHGDKVVAFIRTENEREVAEPSELIEQSL 83  Vibrio cholerae O1 bi...

2IX0_A 103 TRFVGKVQG-KNDRLAIVPDHPLLKDA-IPCRAARGLNH-EFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVP 179 Escherichia coli
P30850  84 TRFVGKVQG-KNDRLAIVPDHPLLKDA-IPCRAARGLNH-EFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVP 160 Escherichia coli K-12
Q8K9Q5  84 NRFVGKIEK-KDNKLFIFPDYPFLKDF-IACRPKKSCVH-VFQTGDWAVAKLIQHKLNGNHIFYAELIEEIVKANNPLIP 160 Buchnera aphidicola s...
P44440  83 TRFIAKVRFnKDKKLQVLVDHPSINQP-IGAQQAKSVKE-ELQEGDWVVANLKTHPLRDDRFFYATINQLICRADDELAP 160 Haemophilus influenza...
Q9KLE1  84 TRFIGRVKL-FKGKLNVAPDHPQLKKLsLKAKTKKGLNEaDFQEGDWVVAHLVRHPLKGDDGFFVQISHKITDANDKIAP 162 Vibrio cholerae O1 bi...
P30850  84 TRFVGKVQG-KNDRLAIVPDHPLLKDA-IPCRAARGLNH-EFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVP 160 Escherichia coli K-12
Q8K9Q5  84 NRFVGKIEK-KDNKLFIFPDYPFLKDF-IACRPKKSCVH-VFQTGDWAVAKLIQHKLNGNHIFYAELIEEIVKANNPLIP 160 Buchnera aphidicola s...
P44440  83 TRFIAKVRFnKDKKLQVLVDHPSINQP-IGAQQAKSVKE-ELQEGDWVVANLKTHPLRDDRFFYATINQLICRADDELAP 160 Haemophilus influenza...
Q9KLE1  84 TRFIGRVKL-FKGKLNVAPDHPQLKKLsLKAKTKKGLNEaDFQEGDWVVAHLVRHPLKGDDGFFVQISHKITDANDKIAP 162 Vibrio cholerae O1 bi...

2IX0_A 180 WWVTLARHNLEKEAPDGVATEMLDEGLV--REDLTALDFVTIDSASTEDMDDALFAKALPD----DKLQLIVAIADPTAW 253 Escherichia coli
P30850 161 WWVTLARHNLEKEAPDGVATEMLDEGLV--REDLTALDFVTIDSASTEDMDDALFAKALPD----DKLQLIVAIADPTAW 234 Escherichia coli K-12
Q8K9Q5 161 WWVTLSRHNLERKEPKIEKDDLILKNNSh-REDLTHLNFITIDNFNTKDIDDALFIEEIHN----GNLRLIVAIADPTSY 235 Buchnera aphidicola s...
P44440 161 WWVTLARHEQSRYPVRGAEPYEMLDQKT--RENLTALHFVTIDSESTMDMDDALYIEPIAQnstqTGWKLVVAIADPTAY 238 Haemophilus influenza...
Q9KLE1 163 WWVTLAENDLPNSEPAGIDDWQLKDDADlvREDLTALPFVTIDGESTKDMDDALYAQQLPN----GDFALTIAIADPTAY 238 Vibrio cholerae O1 bi...
P30850 161 WWVTLARHNLEKEAPDGVATEMLDEGLV--REDLTALDFVTIDSASTEDMDDALFAKALPD----DKLQLIVAIADPTAW 234 Escherichia coli K-12
Q8K9Q5 161 WWVTLSRHNLERKEPKIEKDDLILKNNSh-REDLTHLNFITIDNFNTKDIDDALFIEEIHN----GNLRLIVAIADPTSY 235 Buchnera aphidicola s...
P44440 161 WWVTLARHEQSRYPVRGAEPYEMLDQKT--RENLTALHFVTIDSESTMDMDDALYIEPIAQnstqTGWKLVVAIADPTAY 238 Haemophilus influenza...
Q9KLE1 163 WWVTLAENDLPNSEPAGIDDWQLKDDADlvREDLTALPFVTIDGESTKDMDDALYAQQLPN----GDFALTIAIADPTAY 238 Vibrio cholerae O1 bi...

2IX0_A 254 IAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPVLACRMTLSADGTIEDNIEFFAATIESKAKLVYD 333 Escherichia coli
P30850 235 IAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPVLACRMTLSADGTIEDNIEFFAATIESKAKLVYD 314 Escherichia coli K-12
Q8K9Q5 236 IKSGSKLDITAAKRGFTNYLPGFNVPMLPRSLSEDICSLNPHERRPVLACCITILKDGNICSKINFFLAWIKSKSKLSYD 315 Buchnera aphidicola s...
P44440 239 IALDSQIEQEAKQRCFTNYLPGFNIPMLPRELSDELCSLIANETRPALVCYIETDLTGNITAKPHFVSAYVQSKAKLAYN 318 Haemophilus influenza...
Q9KLE1 239 ITPEDEMDKVARERGFTIYLPGRNIPMLPRDLADELCSLMENQVRPALCCSVTIRKDGVIGDDIRFFAANIKSHARLVYD 318 Vibrio cholerae O1 bi...
P30850 235 IAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPVLACRMTLSADGTIEDNIEFFAATIESKAKLVYD 314 Escherichia coli K-12
Q8K9Q5 236 IKSGSKLDITAAKRGFTNYLPGFNVPMLPRSLSEDICSLNPHERRPVLACCITILKDGNICSKINFFLAWIKSKSKLSYD 315 Buchnera aphidicola s...
P44440 239 IALDSQIEQEAKQRCFTNYLPGFNIPMLPRELSDELCSLIANETRPALVCYIETDLTGNITAKPHFVSAYVQSKAKLAYN 318 Haemophilus influenza...
Q9KLE1 239 ITPEDEMDKVARERGFTIYLPGRNIPMLPRDLADELCSLMENQVRPALCCSVTIRKDGVIGDDIRFFAANIKSHARLVYD 318 Vibrio cholerae O1 bi...

2IX0_A 334 QVSDWLENTG--DWQPeSEAIAEQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEA 411 Escherichia coli
P30850 315 QVSDWLENTG--DWQPeSEAIAEQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEA 392 Escherichia coli K-12
Q8K9Q5 316 NVSDWIEKKS--SWKPeTKSIENQILLLHRLCLLRIKWRTSNAVLFQDSLEYRFQFSETGIVEDVVIEKRRIAHKIIEES 393 Buchnera aphidicola s...
P44440 319 KVSDYLEQADn-AWQPeMPETAQQIHWLHQFTKARIQWRKTHSLFFKEKPDYAFVLAENGKVQEIKAEYRRIANQIVEEA 397 Haemophilus influenza...
Q9KLE1 319 HVSDWLETGSseQWQP-SEEIAQVVRDLYAFSQARANWRETHAVVFPDRPDYRFELSADNDVVAIHADMRRTANRLVEES 397 Vibrio cholerae O1 bi...
P30850 315 QVSDWLENTG--DWQPeSEAIAEQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEA 392 Escherichia coli K-12
Q8K9Q5 316 NVSDWIEKKS--SWKPeTKSIENQILLLHRLCLLRIKWRTSNAVLFQDSLEYRFQFSETGIVEDVVIEKRRIAHKIIEES 393 Buchnera aphidicola s...
P44440 319 KVSDYLEQADn-AWQPeMPETAQQIHWLHQFTKARIQWRKTHSLFFKEKPDYAFVLAENGKVQEIKAEYRRIANQIVEEA 397 Haemophilus influenza...
Q9KLE1 319 HVSDWLETGSseQWQP-SEEIAQVVRDLYAFSQARANWRETHAVVFPDRPDYRFELSADNDVVAIHADMRRTANRLVEES 397 Vibrio cholerae O1 bi...

2IX0_A 412 MIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHG----------LHVDAEEVLTLDGFCKLRRELDAQPTG 481 Escherichia coli
P30850 393 MIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHG----------LHVDAEEVLTLDGFCKLRRELDAQPTG 462 Escherichia coli K-12
Q8K9Q5 394 MIIANISAANFLSKNLGFGIYNTHAGFDPINAENVVSFLNNYN----------LKFTVKEITTLKGFCNLRRVLNILSDN 463 Buchnera aphidicola s...
P44440 398 MIIANICAAQFLHEQAKTGIFNTHSGFDKKFLENAHNFLMANLaneqnqtelaERYSVENLATLNGYCQMRHDIEPIESD 477 Haemophilus influenza...
Q9KLE1 398 MITANICAGKTLQTTFGFGVFNTHAGFKAEKMADVVELMAVNGa---------PNADAETLATVEGFAALRRWLATQETS 468 Vibrio cholerae O1 bi...
P30850 393 MIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHG----------LHVDAEEVLTLDGFCKLRRELDAQPTG 462 Escherichia coli K-12
Q8K9Q5 394 MIIANISAANFLSKNLGFGIYNTHAGFDPINAENVVSFLNNYN----------LKFTVKEITTLKGFCNLRRVLNILSDN 463 Buchnera aphidicola s...
P44440 398 MIIANICAAQFLHEQAKTGIFNTHSGFDKKFLENAHNFLMANLaneqnqtelaERYSVENLATLNGYCQMRHDIEPIESD 477 Haemophilus influenza...
Q9KLE1 398 MITANICAGKTLQTTFGFGVFNTHAGFKAEKMADVVELMAVNGa---------PNADAETLATVEGFAALRRWLATQETS 468 Vibrio cholerae O1 bi...

2IX0_A 482 FLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGETATR-PQDEITVQMAERRRLNRMA 560 Escherichia coli
P30850 463 FLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGETATR-PQDEITVQMAERRRLNRMA 541 Escherichia coli K-12
Q8K9Q5 464 YINSRIRRYQSFGDFSITPSPHFALGLVEYATWTSPIRKYSDMINHRLLKSIINQDTNITkPSEDIKLKISEQKRRNRIA 543 Buchnera aphidicola s...
P44440 478 YLELRLRRYLTFAEFKSELAPHFGLGLEGYATWTSPIRKYSDMVNHRLIKAVLAKQPYEK-PQNDVLARLQEARRQNRLV 556 Haemophilus influenza...
Q9KLE1 469 YLDNRIRKYQSYSEIGNQPLPHFAMGLDVYATWTSPIRKYGDMINHRLLKAHILGKAPVQtPDETVGEELALHRKHHKIA 548 Vibrio cholerae O1 bi...
P30850 463 FLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGETATR-PQDEITVQMAERRRLNRMA 541 Escherichia coli K-12
Q8K9Q5 464 YINSRIRRYQSFGDFSITPSPHFALGLVEYATWTSPIRKYSDMINHRLLKSIINQDTNITkPSEDIKLKISEQKRRNRIA 543 Buchnera aphidicola s...
P44440 478 YLELRLRRYLTFAEFKSELAPHFGLGLEGYATWTSPIRKYSDMVNHRLIKAVLAKQPYEK-PQNDVLARLQEARRQNRLV 556 Haemophilus influenza...
Q9KLE1 469 YLDNRIRKYQSYSEIGNQPLPHFAMGLDVYATWTSPIRKYGDMINHRLLKAHILGKAPVQtPDETVGEELALHRKHHKIA 548 Vibrio cholerae O1 bi...

2IX0_A 561 ERDVGDWLYARFLKDKAGTDTRFAAEIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVT 640 Escherichia coli
P30850 542 ERDVGDWLYARFLKDKAGTDTRFAAEIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVT 621 Escherichia coli K-12
Q8K9Q5 544 ERDISDWLYTLLLQKKEFKNKKFNAEIIDVSRSGIRAKLLENGANVFIPALFLHPIREELVFNQETGKVFIKGVLYYKIS 623 Buchnera aphidicola s...
P44440 557 ERDIADWLYCRYLADKVASNAEFEAEVQDVMRAGLRVQLLENGASLFIPAATLHNNKEEIQLNPDELALYIKGERTYKIG 636 Haemophilus influenza...
Q9KLE1 549 ERNVADWLYARTLADEPAKETRFQAEIFDINRPGMRVRLLENGAMAFIPGALILDNKERIECNGEDGTVLIDKEVVYKLG 628 Vibrio cholerae O1 bi...
P30850 542 ERDVGDWLYARFLKDKAGTDTRFAAEIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVT 621 Escherichia coli K-12
Q8K9Q5 544 ERDISDWLYTLLLQKKEFKNKKFNAEIIDVSRSGIRAKLLENGANVFIPALFLHPIREELVFNQETGKVFIKGVLYYKIS 623 Buchnera aphidicola s...
P44440 557 ERDIADWLYCRYLADKVASNAEFEAEVQDVMRAGLRVQLLENGASLFIPAATLHNNKEEIQLNPDELALYIKGERTYKIG 636 Haemophilus influenza...
Q9KLE1 549 ERNVADWLYARTLADEPAKETRFQAEIFDINRPGMRVRLLENGAMAFIPGALILDNKERIECNGEDGTVLIDKEVVYKLG 628 Vibrio cholerae O1 bi...

2IX0_A 641 DVIDVTIAEVRMETRSIIARP 661 Escherichia coli
P30850 622 DVIDVTIAEVRMETRSIIARP 642 Escherichia coli K-12
Q8K9Q5 624 DLITVVLSEIRLQTRSIIARI 644 Buchnera aphidicola str. Sg (Schizaphis graminum)
P44440 637 DMVKVKLTEVKEATRSIVGEI 657 Haemophilus influenzae Rd KW20
Q9KLE1 629 DVLEIVLTEVNQENRSLVGKP 649 Vibrio cholerae O1 biovar El Tor str. N16961
P30850 622 DVIDVTIAEVRMETRSIIARP 642 Escherichia coli K-12
Q8K9Q5 624 DLITVVLSEIRLQTRSIIARI 644 Buchnera aphidicola str. Sg (Schizaphis graminum)
P44440 637 DMVKVKLTEVKEATRSIVGEI 657 Haemophilus influenzae Rd KW20
Q9KLE1 629 DVLEIVLTEVNQENRSLVGKP 649 Vibrio cholerae O1 biovar El Tor str. N16961
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