2P4Q_A 12 DFGLIGLAVMGQNLILNAADHGFTVCAYNRTQSKVDHFLANEAKGKSIIGATSIEDFISKLKRPRKVMLLVKAGAPVDAL 91 baker's yeast P53319 7 DLGLVGLAVMGQNLILNAADHGFTVVAYNRTQSKVDRFLANEAKGKSIIGATSIEDLVAKLKKPRKIMLLIKAGAPVDTL 86 Saccharomyces cerevis... P43774 6 DIGVIGLAVMGQNLILNMNDHGFKVVAYNRTTSKVDEFLQGAAKGTNIIGAYSLEDLAAKLEKPRKVMLMVRAGDVVDQF 85 Haemophilus influenza... O83351 4 DIGFIGLAVMGENLVLNIERNGFSVAVFNRTTTVVDRFLAGRAHGKRITGAHSIAELVSLLARPRKIMLMVKAGSAVDAV 83 Treponema pallidum su... Q9Z8I3 4 NIGLIGLAVMGKNLVLNMIDHGFSVSVYNRTPEKTRDFLKEYPNHRELVGFESLEDFVNSLERPRKIMLMIQAGKPVDQS 83 Chlamydia pneumoniae O84066 6 DIGLIGLAVMGKNLVLNMVDHGFSVSVYNRSPAKTEEFLKDHGESGALQGFTTIQEFVQSLKRPRKIMIMIKAGAPVDEM 85 Chlamydia trachomatis... P00350 5 QIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIAE-NPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAA 83 Escherichia coli K-12 P52208 12 TFGVIGLAVMGENLALNVESRGFPIAVFNRSPNKTEKFMAERAVGKDIKAAYTVEEFVQLLERPRKILVMVKAGGPVDAV 91 Synechocystis sp. PCC... P12013 4 SIGVIGLGVMGSNIALNMANKGENVAVYNYTRDLTDQLIQK-LDGQSLSPYYELEDFVQSLEKPRKIFLMVTAGKPVDSV 82 Bacillus subtilis sub... P38720 4 DFGLIGLAVMGQNLILNAADHGFTVCAYNRTQSKVDHFLANEAKGKSIIGATSIEDFISKLKRPRKVMLLVKAGAPVDAL 83 Saccharomyces cerevis... 3FWN_A 17 QIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIAE-NPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAA 95 Escherichia coli K-12
2P4Q_A 92 INQIVPLLEKGDIIIDGGNSHFPDSNRRYEELKKKGILFVGSGVSGGEEGARYGPSLMPGGSEEAWPHIKNIFQSISAKS 171 baker's yeast P53319 87 IKELVPHLDKGDIIIDGGNSHFPDTNRRYEELTKQGILFVGSGVSGGEDGARFGPSLMPGGSAEAWPHIKNIFQSIAAKS 166 Saccharomyces cerevis... P43774 86 IEALLPHLEEGDIIIDGGNSNYPDTNRRVKALAEKGIRFIGSGVSGGEEGARHGPSIMPGGNQEAWQYVKPIFQAISAKT 165 Haemophilus influenza... O83351 84 IDQILPLLEKGDLVIDGGNSHYQDTIRRMHALEAAGIHFIGTGVSGGEEGALRGPSLMPGGSAQAWPLVSPIFCAIAAKA 163 Treponema pallidum su... Q9Z8I3 84 IHALLPFLEPGDVIIDGGNSYFKDSERRCKELQEKGILFLGVGISGGEEGARHGPSIMPGGNPEAWPLVAPIFQSIAAKV 163 Chlamydia pneumoniae O84066 86 IASLLPFLEEGDILIDGGNSYYLDSEQRYVDLKKEGILFVGMGVSGGEEGARKGPSIMPGGNIDAWPAIAPIFQSIAAQV 165 Chlamydia trachomatis... P00350 84 IDSLKPYLDKGDIIIDGGNTFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIAAVA 163 Escherichia coli K-12 P52208 92 INELKPLLEEGDMIIDGGNSLYEDTERRTKDLEATGLGFVGMGVSGGEEGALLGPSLMPGGTPAAYKELEPILTKIAAQV 171 Synechocystis sp. PCC... P12013 83 IQSLKPLLEEGDVIMDGGNSHYEDTERRYDELKEKGIGYLGVGISGGEVGALTGPSIMPGGDRDVYEKAAPILTKIAAQV 162 Bacillus subtilis sub... P38720 84 INQIVPLLEKGDIIIDGGNSHFPDSNRRYEELKKKGILFVGSGVSGGEEGARYGPSLMPGGSEEAWPHIKNIFQSISAKS 163 Saccharomyces cerevis... 3FWN_A 96 IDSLKPYLDKGDIIIDGGNTFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIAAVA 175 Escherichia coli K-12
2P4Q_A 172 -D---GEPCCEWVGPAGAGHYVKMVHNGIEYGDMQLICEAYDIMKRLGGFTDKEISDVFAKWNN-GVLDSFLVEITRDIL 246 baker's yeast P53319 167 -N---GEPCCEWVGPAGSGHYVKMVHNGIEYGDMQLICEAYDIMKRIGRFTDKEISEVFDKWNT-GVLDSFLIEITRDIL 241 Saccharomyces cerevis... P43774 166 -Eq--GEPCCDWVGGEGAGHFVKMVHNGIEYGDMQLICEAYQFLKEGLGLSYEEMQAIFAEWKN-TELDSYLIDITTDIL 241 Haemophilus influenza... O83351 164 -Dd--GTPCCDWVGSDGAGHYVKMIHNGIEYGDMQIIAEGYWFMKHALGMSYEHMHHTFTRWNT-GRLHSYLIEITAAIL 239 Treponema pallidum su... Q9Z8I3 164 -Q---GRPCCSWVGTGGAGHYVKAVHNGIEYGDIQLICEAYGILRDFLKLSATAVATILKEWNT-LELESYLIRIASEVL 238 Chlamydia pneumoniae O84066 166 -D---GRPCCSWIGTGGAGHFVKAVHNGIEYGDIQLICETYEILKTRLNLSLEQIGNIFFEWNQ-TDLNSYLIGAAAAVL 240 Chlamydia trachomatis... P00350 164 -Ed--GEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLTNEELAQTFTEWNN-GELSSYLIDITKDIF 239 Escherichia coli K-12 P52208 172 -EdpdNPACVTFIGPGGAGHYVKMVHNGIEYGDMQLIAEAYDILKNGLGLSNEQLHEVFGQWNQtDELNSFLIEISTDIF 250 Synechocystis sp. PCC... P12013 163 -G---DDPCCVYIGPKGAGHFTKMVHNGIEYADMQLIAEAYTFLRETLRLPLDEIASIFETWNQ-GELKSYLIEITAEIL 237 Bacillus subtilis sub... P38720 164 -D---GEPCCEWVGPAGAGHYVKMVHNGIEYGDMQLICEAYDIMKRLGGFTDKEISDVFAKWNN-GVLDSFLVEITRDIL 238 Saccharomyces cerevis... 3FWN_A 176 eD---GEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLTNEELAQTFTEWNN-GELSSYLIDITKDIF 251 Escherichia coli K-12
2P4Q_A 247 KFDDVD-GKPLVEKIMDTAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSALKNERIRASKVLPG-PEVPKDAVk--- 321 baker's yeast P53319 242 KFDDVD-GKPLVEKIMDTAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSAIKDERKRASKLLAG-PTVPKDAIh--- 316 Saccharomyces cerevis... P43774 242 GYKDAS-GEPLVEKILDTAGQKGTGKWTGINALDFGIPLTLITESVFARCVSSFKDQRVAANQLFGK-TITPVEG----- 314 Haemophilus influenza... O83351 240 AHQDTD-GTPLLEKILDAAGQKGTGRWTCVAALEEGSPLTLITESVMARSLSAQKQARCKAHRVFGS-PVKVSKAEtlsa 317 Treponema pallidum su... Q9Z8I3 239 ALKDPE-GIPVIDTILDVVGQKGTGKWTAIDALNSGVPLSLIIGAVLARFLSSWKEIREQAARNYPGtPLIFEMPH---- 313 Chlamydia pneumoniae O84066 241 IAKDEN-GNAIASTILDVAGQKGTGRWVAEDAIKAGVPMSLIIESVLARYLSTWKEVRTKAAQEFPGiPLLCQPPQ---- 315 Chlamydia trachomatis... P00350 240 TKKDED-GNYLVDVILDEAANKGTGKWTSQSALDLGEPLSLITESVFARYISSLKDQRVAASKVLSG-PQAQPAG----- 312 Escherichia coli K-12 P52208 251 AKKDPEtGGHLIDYILDAAGQKGTGRWTVMSGLELGVPIPTIYAAVNARVMSSLKEERVAASGQLSG-PSKTFSG----- 324 Synechocystis sp. PCC... P12013 238 RKKDEKtGQPLIDVILDKTGQKGTGKWTSMQAIDNGIPSTIITESLFARYLSSLKEERMAAQDVLAG-PEAEEKHL---- 312 Bacillus subtilis sub... P38720 239 KFDDVD-GKPLVEKIMDTAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSALKNERIRASKVLPG-PEVPKDAVk--- 313 Saccharomyces cerevis... 3FWN_A 252 TKKDED-GNYLVDVILDEAANKGTGKWTSQSALDLGEPLSLITESVFARYISSLKDQRVAASKVLSG-PQAQPAG----- 324 Escherichia coli K-12
2P4Q_A 322 -DREQFVDDLEQALYASKIISYAQGFMLIREAAATYGWKLNNPAIALMWRGGCIIRSVFLGQITKAYREEPDLENLLFNK 400 baker's yeast P53319 317 -DREQFVYDLEQALYASKIISYAQGFMLIREAARSYGWKLNNPAIALMWRGGCIIRSVFLAEITKAYRDDPDLENLLFNE 395 Saccharomyces cerevis... P43774 315 -DKKVWIEAVRKALLASKIISYAQGFMLIREASEQFGWDINYGATALLWREGCIIRSRFLGNIRDAYEANPNLVFLGSDS 393 Haemophilus influenza... O83351 318 qQREELVSALEDALYCAKIVSYAQGFELLSHTAKRRGWTLDFSRIASLWRGGCIIRSGFLSKISAAFAQQHDLENLVLAP 397 Treponema pallidum su... Q9Z8I3 314 -DPSVFIQDVFHALYASKIISYAQGFMLLGEASKEYNWGLDLGEIALMWRGGCIIQSAFLDVIHKGFAANPENTSLIFQE 392 Chlamydia pneumoniae O84066 316 -EASAFIEDVREALYAAKIISYAQGFMLLKQVSQDKGWDLNLGELALIWRGGCIIQSAFLDKIHQGFENSPEAHSLILQD 394 Chlamydia trachomatis... P00350 313 -DKAEFIEKVRRALYLGKIVSYAQGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAP 391 Escherichia coli K-12 P52208 325 -DVEAWIPKVRDALYCSKMCSYAQGMALIAKASQEFGYDVNLPEIARIWKGGCIIRAGFLDKIKKAFKDNPQLPNLLLAP 403 Synechocystis sp. PCC... P12013 313 -DKDTWIEYVRQALYMGKVCAYAQGFAQYKMSSELYGWNLPLKDIALIFRGGCIIRADFLNVISEAFSEQPNLANLLIAP 391 Bacillus subtilis sub... P38720 314 -DREQFVDDLEQALYASKIISYAQGFMLIREAAATYGWKLNNPAIALMWRGGCIIRSVFLGQITKAYREEPDLENLLFNK 392 Saccharomyces cerevis... 3FWN_A 325 -DKAEFIEKVRRALYLGKIVSYAQGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAP 403 Escherichia coli K-12
2P4Q_A 401 FFADAVTKAQSGWRKSIALATTYGIPTPAFSTALSFYDGYRSERLPANLLQAQRDYFGAHTFrvlpeCASDnLPVDKDIH 480 baker's yeast P53319 396 FFASAVTKAQSGWRRTIALAATYGIPTPAFSTALAFYDGYRSERLPANLLQAQRDYFGAHTFrilpeCASAhLPVDKDIH 475 Saccharomyces cerevis... P43774 394 YFKGILENALSDWRKVVAKSIEVGIPMPCMASAITFLDGYTSARLPANLLQAQRDYFGAHTY-----ERTD-KPRGEFFH 467 Haemophilus influenza... O83351 398 FFAEELKRACPGWRTIVAESVRQALPVPALSAALAWFDGFTGAALPANLLQAQRDYFGAHTY-----ERTD-APRGEFFH 471 Treponema pallidum su... Q9Z8I3 393 YFRGALRHAEMGWRRTVVTAIGAGLPIPCLAAAITFYDGYRTASSSMSLAQGLRDYFGAHTY-----ERND-RPRGEFYH 466 Chlamydia pneumoniae O84066 395 YFKKVLFDSETGFRRAVLHAIGSGVAIPCLSSALSFYDGYRTVDSSLFLVQGLRDYFGAHGY-----ERRD-CPRGEFYH 468 Chlamydia trachomatis... P00350 392 YFKQIADDYQQALRDVVAYAVQNGIPVPTFSAAVAYYDSYRAAVLPANLIQAQRDYFGAHTY-----KRID-KEG--VFH 463 Escherichia coli K-12 P52208 404 EFKQSILDRQGPWREVLMLANEMGIAVPAFSSSLDYFDSYRRAVLPQNLTQAQRDYFGAHTY-----ERTD-KPRGEFFH 477 Synechocystis sp. PCC... P12013 392 YFTDKLHAYQTGLRKVVCEGISTGISFPCLTTALSYYDGYRTGRSNANLLQAQRDYFGAHTY-----ERTD-MDG--VFH 463 Bacillus subtilis sub... P38720 393 FFADAVTKAQSGWRKSIALATTYGIPTPAFSTALSFYDGYRSERLPANLLQAQRDYFGAHTFrvlpeCASDnLPVDKDIH 472 Saccharomyces cerevis... 3FWN_A 404 YFKQIADDYQQALRDVVAYAVQIGIPVPTFSAAVAYYDSYRAAVLPANLIQAQRDYFGAHTY-----KRID-KEG--VFH 475 Escherichia coli K-12
2P4Q_A 481 INWTG 485 baker's yeast P53319 476 INWTG 480 Saccharomyces cerevisiae S288c P43774 468 TNWTG 472 Haemophilus influenzae Rd KW20 O83351 472 TNWTG 476 Treponema pallidum subsp. pallidum str. Nichols Q9Z8I3 467 TDWVH 471 Chlamydia pneumoniae O84066 469 TDWLE 473 Chlamydia trachomatis D/UW-3/CX P00350 464 TEWLD 468 Escherichia coli K-12 P52208 478 TEWLD 482 Synechocystis sp. PCC 6803 substr. Kazusa P12013 464 TNWSE 468 Bacillus subtilis subsp. subtilis str. 168 P38720 473 INWTG 477 Saccharomyces cerevisiae S288c 3FWN_A 476 TEWLD 480 Escherichia coli K-12
Jiyao W et al.(2023). "The conserved domain database in 2023.",