Conserved Protein Domain Family
DUF1512

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pfam07431: DUF1512 
Protein of unknown function (DUF1512)
This family consists of several archaeal proteins of around 370 residues in length. The function of this family is unknown.
Statistics
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PSSM-Id: 400008
Aligned: 28 rows
Threshold Bit Score: 344.947
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_013336583          26 ISTIIWLIIFVLLlTP-YFQNYMAIMWYSYSVGNFLTSLSRLIMNNVNLVINHINQLLksngssQSTNKSLVEkTIqdlM 104 Vulcani...
Q8TXZ0                19 VSIILFWLFIRVYyQV----------VLFRRIEGEVERIRKIDEKVQQMVVRRARc-------dREEAETLVQ-RA---A 77  Methano...
WP_013413311           8 tGLILLLIFLIIF-------PMVMNQMLLRNVSRYVEEMEKKVEEAEKLIIKMCKRKHs-----KE-----LK-KF---L 66  Methano...
jgi:Tpen_0702          6 LSFIMWLVALAIFsYI---TQEMQILKAISEVEGYVALFRGIRDKAVKVLVDQFSKYTas---sEGASRDVLEqRIlslI 79 
Q8ZX58                15 ISMLIWFALIFML-------QDLQMWRYLSQVSGFLSYLGQLLNAASANVLNALDKVKr-----KEVQRAELEsTLkkmV 82  Pyrobac...
CCC81680              16 ITTIIWFAAIYIY------QEFYYIQRPLWQIGGFLSYLGQMIRSASNDIGNHLERLKr-----QGVGRKDVDdVIkrmL 84 
BAJ47208              22 LLSLVWFAFLMIFfLYpSFGQRMQLSYMLRDLEKKLNKLKLIKDEINQITVETIKRVGk----pEKDPAPDIN-RL---S 93 
goetting:Ngar_c21250   2 wVYIISIAIIPFFmMY-A--QKFQSRVILGEISKSLVKLKTMKEGARKEAVDYIKTTVktttspSSDPAAGVD-RF---L 74 
jgi:Nmar_0599         21 lMMLIWILPIVIFiFY-G--QRIQLYVTSGEIKKGIKKLDGFREESRNELITYINKHLs----pKNNPEKKID-QF---L 89 
ABK77856              12 LMMLVWIIPIILFvFY-G--QRIQLYVTSNQIKKDVAKLLKYRDESEGALAEFAGGPG----------------GMsglL 72 
WP_013336583         105 EFVVIEPVSAEPTGLMRTLKLLVTSYNEKLEDSIRTLLPNIDRPLVQNVVDAVDGLRELNYIYKVIMHYYRLSNKYKNPY 184 Vulcani...
Q8TXZ0                78 NLFVVQPVQLDPHGIIERLENLIERSEDKFRSYARVLTGKRDGVEVDNMSMALTCVFSIHVIAQYLRHLLLSAKKTNNIQ 157 Methano...
WP_013413311          67 EFFVAKPSRLDPHGIVKRFEKILNMSEKRFKEVADKVLEDLDEEKKSNFIMALKSTLSLKSTAKIIRHNLELAKKTKNFQ 146 Methano...
jgi:Tpen_0702         80 ETRIILPVDLDPYGIVRKIKHVLRTSEVELEKEVSRIAKGASRTEVQRLSSLVEVARELNLVYKLVNHYYLIARKFKSLW 159
Q8ZX58                83 DFAVIEPTALDPNGIVPKFKHILNTYVDTYEGEIRRLVE--DGVLVKNLTTAVEALRYMNFIYKIVDHYYKTARKYKAFY 160 Pyrobac...
CCC81680              85 DFTVIPPTSLDPFGIVPKYKNILNAYETAAESEVAKLV-GDNTVSVKNVSTALEALREINFLYKIVDHYYRIARKYKLYV 163
BAJ47208              94 EFFIIQPESMDPYGLVYKLEHILETGESVYEQEVAKLAPHATEHQVKSLTNLVEVLRGINTIYRVVRHYYLLGKKTANIY 173
goetting:Ngar_c21250  75 EYFAIMPVDLDPNGIVRKLDHIMRVRDDRLRAEVRKLCAGASDQEVSKIENILEAATALNMIYKIVRHFYLMGKRTTSMF 154
jgi:Nmar_0599         90 EYFTIMPVDMDPNGIVEKVQHTVRSREDYTREHVKSLFSEINEIELSKVQTLLEIASSLQMIHKIINHMFLTAKKQNNYP 169
ABK77856              73 DYFTIMPVDMDPAGIVPKLRHIVRSREDLTRARVKSMHPGADELEISRMLTLLEIASVLRLLHKTVNHLYLTAKRQNNFP 152
WP_013336583         185 LMMQVYMLLPIIREYVNALNGAITTFLKGQPVGDAAGPLTAYRFMRGcsGLTELTHNIKDTYIGLCDFEGRRVYVIKARG 264 Vulcani...
Q8TXZ0               158 LLLLITMLLPTFKQFVKSNYEGAKAFLKCVPIGDSVGPMVAARLI----GDSPVREVEKGTVAAEKELEGRRLLIVKAHG 233 Methano...
WP_013413311         147 ILIALQMNLNLIRRFFEAQFEGVKAFSKGLPVGDSAGVVVAGALMD----GNDDLKEMGDMVYTKKSIDGRNVIIVRSKG 222 Methano...
jgi:Tpen_0702        160 LVLQLNAQMPFVLEEVKAIEGALESFSKGIPVGDSAGPLVAALLARK--YKGSFVEPVKDTEISQVTVDGKKVFIVKAKG 237
Q8ZX58               161 LVIQLTMLLPLLKELTDTVNEAVNSFIKGVPIGDSAGPLVAYNVLSQc-GGVVYHHDVKDTVVAECEYQGRKLYVIKAKG 239 Pyrobac...
CCC81680             164 YAMQLSMLLPILKEVSDALNGAVSAFLKGLPVGDSAGPMVAYNVSKTc-SQPIVHDGIKDTSITECDFEGRRLFIIKARG 242
BAJ47208             174 MVLQIQMVLPQIIEIAESYRQAAVAFSKGQPIGDGVGPLVAAKLVNG--MEKERYEIAKDTVVQEIELENRKVYVVRAIG 251
goetting:Ngar_c21250 155 VLVQLQMVMPLLLEEAEALQKAINAFKRGQPIGDGIGPMVVGKMMLG--KEKK--LAARETVYSEDEYKGRKLYLLKAEG 230
jgi:Nmar_0599        170 LILPLQMILPFIMEQAEAMKEAIPVFKTGQPVGDGIGPMVVGKMMLN--SPKE--IISFQTALAQTTFENRNLFLLKAEG 245
ABK77856             153 LILPLQMALPFVMEQAEAFRDAVPAFRAGQPVGDGIGPMVVGRMMLG--AAKN--EAAFQTVWAEAKSEGRWLYLLKARG 228
WP_013336583         265 PGGTVGNLDDGIIYLIERVGVKPRMIITVDAALKFEGEKTGSIAEGIGVAMGGIGVERFNIERTASKYGIPLYAILIKMG 344 Vulcani...
Q8TXZ0               234 PGGNLGRLGRAVKKLVREY-GDVSKIITIDAALKLEGEKTGKVSEGVGVAMGDPGHESYKIEQIAADEGIDLDAVAIKMS 312 Methano...
WP_013413311         223 PGARIGRVGRVVTRLIDKN--NIDHLIMIDAAVKLEGEKTGSVAEGVGVVVGGTGVEKWLIENKITEKDIDVSSVIIKMS 300 Methano...
jgi:Tpen_0702        238 PGSTTGHLEEALSWIFSRE--KVSLIVSVDAALKLEGEESGSVASGYGVAMGGIGVERFEIEELSTKHGVPLFAVLIKMS 315
Q8ZX58               240 SGSTVGRLDEAVEYVFQRLDARPKYIVTIDAALRLEGERTGEIAEGIGVAMGGVGVEKFNIESYATKYGVPLYAFLIKMR 319 Pyrobac...
CCC81680             243 PGSTVGRPDEGVEFVFEKLGVRPKYIITVDAALKLEGERTGDIAEGVGVAMGGVGAEKFNIEGIATKYGVPLYAFLIKMR 322
BAJ47208             252 PGGTVGRPGEGVKQLVERLPENPKLIITIDAALKLEGEETGKIAEGVGVAIGGPGVDKYKIEELAKSRGIPLYAFVIFQS 331
goetting:Ngar_c21250 231 PAGTVGRPGEAITRLAGDMGIKIDAIIMIDAALKLEGERTGEVAEGIGAAIGGIGVEKYQIEEVATRLDIPVYAVIVKQS 310
jgi:Nmar_0599        246 PGSTVGRPSDALQSIVSKN--KIDAVIMIDAALKMEGEDSASIARGFGAAIGGIGTEKFHIEAVATDNQIPIFSIVVKQS 323
ABK77856             229 PESTVGRLGEAAKSIIEQR--RPDAVIMVDAALMMEGEESASVARGFGAAIGGLGIERFEIEEAAAAAGIPVYSIIVRQS 306
WP_013336583         345 LPEALSAMTKDVEGAVNEAVERVKRVIRESVReGEEVILIGVGNTGGVA 393 Vulcanisaeta distributa
Q8TXZ0               313 ATEAVMPMPKSVVDAVEEAAERALELAKEAPEdS-TVIIVGVGNTVGIP 360 Methanopyrus kandleri
WP_013413311         301 LEEAVSQMNKKILEGCKKAIKIVNKMIERYEKdS-NILVVGVGNSSGIP 348 Methanothermus fervidus
jgi:Tpen_0702        316 EAEALSVMTEKVYQGVQQAVRIVEDII-SRAPeGSSIVVLGVGNSLGVP 363
Q8ZX58               320 QSEALTTMTSDIYNAVGQTTKRVLDFILNNVApGESVLVIGVGNTVGVG 368 Pyrobaculum aerophilum
CCC81680             323 EAEALTAMTKEIYEAVQMVSKRVVDFLREKTQpGDAVVLVGVGNTVGVA 371
BAJ47208             332 ITEAITPMRESIAKAADQVLEKVKQLILEKVKsGESVVVAGIGNTIGVG 380
goetting:Ngar_c21250 311 VQDAITIMRKEIADAFDKVTNTVYSVIEDKTSeGQSVMVIGVGNTMGVG 359
jgi:Nmar_0599        324 VKEAITLMTKEIADQADDVRSQVYEIILENTKeGQSVVVIGVGNTIGVP 372
ABK77856             307 AKEAVGLMPKSVAEAADGVRVQLLEMIRDSTTeGEAVLVIGVGNTAGIS 355
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