4UXV


Conserved Protein Domain Family
EzrA

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pfam06160: EzrA 
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Septation ring formation regulator, EzrA
During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Statistics
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PSSM-Id: 428797
Aligned: 56 rows
Threshold Bit Score: 396.147
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4UXV_A           1 GSHMRKKIYAEIDRLESWKIEILNRSIVEEMSKIKHLKMTG-QTEEFFEKWREEWDEIVTAHMPKVEELLYDAEENADKY 79  Bacillus subt...
CCZ23176        34 rLLKLKHYRNEIVDLENKMNAIKSLPIQYRLGRVKGIAKNMpELQEKYETYDAKFAELTDLQNDEIIPLVNDIDEALYYR 113
CDE29004        34 hSIKLKIYRQEILDLQNQINGIKTLPLQYRLGRVQSIAKNMpEVAEEYEQFTKDFEKITEFQKNELGVLVNEVDESLFYG 113
EDP11281        35 MVMRKKQTIKQLEQLEQRYNTLKGIPLAFKLNKAVALSRVNeAMSTVVEECKTDFDEVQE-KLKTCSVDLAECDDLIYGH 113
CDD51512        42 RTIRSRKANKRINDLELEVNEIRNNSLQYKFNKASAFARVNdDIMERVKNLTPKYKTCVD-SVVDCETLFTEADDYLAGH 120
CDA33616        38 NSMRRRKAASRFEELEKEVNEVRNNSLDYKFNKAKAFSKANaDIMERVNELSPKYKICIK-GMDDCDTLCERANDYLDGH 116
jgi:EAT1b_0689  23 SMLIRRNFYQKIDDLDMRKQSVLSASIPVELQKFKQWPMEG-ETKEKFDRWHQSWDELVSVHAGQIDEALYRAEEDLDKY 101
BAH18095        19 LFYMRNQRRTHIESIEARKNEVKHLPFQDELVKIKSLNLKG-QAALHFEKWKKEWQTVLNEDIKACELIINDADEALDKF 97 
B9DRR4          23 GVIIRKRNDSMIGTLEDRKQHLFGLPVNEEIEEVKELHLIG-QSQTSFREWNQKWVDLTLNSFADIENHLFEAEKYNDTF 101 Streptococcus...
A4VWI6          23 CLIVRKRNDNLLVALEERKEELFNLPVNEEVETVKALHLIG-QSQVSFREWNQKWVDLSLNSFADIENHIFEAEGYNNAF 101 Streptococcus...
4UXV_A          80 RFKKANQVLVHIDDLLTAAESSIEKILREISDLVTSEEKSREEIEQVRERYSKSRKNLLAYSHLYGELYDSLEKDLDEIW 159 Bacillus subt...
CCZ23176       114 KLRGVQKKMNSLEEKVIHYAKESKQLLKDIEVITEIENIQRLEIIKVKEKYRATNDNYAQIRFKVEDYVPKVQDVFHDID 193
CDE29004       114 KTHGIKKKLALIHEMTQRYDHDAKDLLTRIEKVTEIENIQRVEIIRVKGKYREVGNEYEKIRVKVEEFVPHALEMFKELD 193
EDP11281       114 KVKAARRRLNELSDDLALCETDVNKIHTVLDDILEQENEQRVHINALKETFRKVKKTIHENRTAYSQSYEYLETEIIAIE 193
CDD51512       121 RIKKAMRSMDELETVIDETKERIRIVTQSLDHILKKETEVREQANALKERYGNVKKVYNDNRSSYYSAAEYIDNALNVIE 200
CDA33616       117 RTKKAMRTMDELETCLDDARERIRIVTKALDNILEKETEVRDFANALKERFASVKTVYQNNRPAYFKATTYFDSRIQEIE 196
jgi:EAT1b_0689 102 RFMKVKADLNATEQLIEELETMVHAMLDEMDEFTTHHTSLMDIVKQDEKELYQFRKTLNSQNHAFGPTYALVEQEIAAAE 181
BAH18095        98 KFKESETKVQEADRLLDHIEKKYGQSVEEIKAFMNKTDDDKRMYDACKIIYRESKRDVLANRHQYGESAEPLEAQIEKYE 177
B9DRR4         102 NFIRAKHEINNVESQLNLVEEDITSIREALSILKEQEEKNSARVTHALDLYEKLQSSVAENDSHFGTTKPEIEKQMKNIE 181 Streptococcus...
A4VWI6         102 RFVSAKNAIDSIDSQIDLIEEDIASIRQGLMELKEQEEKNSGRVKHALNLFDSLQEAVRENPDSYGETLSELEKQLKNIE 181 Streptococcus...
4UXV_A         160 SGIKQFEEETEGGNYITARKVLLEQDRNLERLQSYIDDVPKLLADCKQTVPGQIAKLKDGYGEMKEKGYKLEHIQLDKEL 239 Bacillus subt...
CCZ23176       194 ERFVELENYMNNQQFEEAKTYTEDISKYIDALDQQLSDLPTYISVVRQYLPKRLNELKSIMQDMQEKDFAVERMNATIRI 273
CDE29004       194 DDFVKLETLMNNQMFADAKNFTEEIENRIDSLQENLKDLPSYVYVVSDLLPSKIDKVDELITSLEGDEYALEEMNIAARR 273
EDP11281       194 KMFSKFEEWMFASEFNKAADQQKEIKESITRLNEIVEALPSLYERAKGILPRAIDEVGYNYARAKNKGVLLEHLEVSKNL 273
CDD51512       201 DEFSNFEEWMFASEFNKAKEEQEKISKMVDDISSKIAACPGYYEKAKVVLPRALEEVKATMKQMELEKIDLSYLEPEQKI 280
CDA33616       197 NEFTSFEEWMYASEFNKAKDEGDKIAKEIDVVSSEVASCPDLYERAMAIIPAAVNEIRENEAELTKANVDLAYLETDKKL 276
jgi:EAT1b_0689 182 AKRSEMINLKQVGQVSEAFETGQALSNQVGHIRELIRVIPQFVRTVQVELKQQLQQLRAGHKEMQMDGYALEPLGLMEEI 261
BAH18095       178 PQINVYQTLIDEGNYDDAHMHINRLHEEMSLLKKDMEEIPELIRDVQKELPAQFQDIKFGCRDLKIEGYNIEHVKVDSTL 257
B9DRR4         182 TEFSQFVTLNSSGDPVEASEVLDRAEEHTIALGQITEQIPAIVAKLEDEFPDQLDDLESGYRRLLEDNYHFAENNIEEKF 261 Streptococcus...
A4VWI6         182 VEFSEFVMLNSSGDPIEASEILDKTEEHMIALNQIMDRIPSLIERVTKDFPEQLEDLESGYRKLVEQNYLFTEANIESQF 261 Streptococcus...
4UXV_A         240 ENLSNQLKRAEhVLMTELDIDEASAILQLIDENIQSVYQQLEGEVEAGQSVLSKMPELIIAYDKLKEEKEHTKAETELVK 319 Bacillus subt...
CCZ23176       274 SKIDNDLHETE-KNIKNLKLENVGQNIEVMTDELNLLYSDFEKEKNAYALYEEKRNECYKFVNKIESGLLEAKESIHELE 352
CDE29004       274 QEVDEQMEESI-AHVKNVDIKGAAEVLEPLTGLIEELVIDLGKELDSYKQFKEKWRESYNELQRLTDVYQNTMKEYRRLI 352
EDP11281       274 DVISDMLKNDL-NRLHSGTPENVKEDLDDLEVRIAQLAEQIRLEEEAFDEVNDGLTALFDSIREVNCEFDDIKSLYARVY 352
CDD51512       281 NAIENALEKTI-SLLDTGNFDQASDALDEIGDHILALQDDILNEKHAYDEIHGNLEETLSVVDQIEVELKEIVNLYTNIK 359
CDA33616       277 NTVSENLQASI-HLIDIGNLADAQMVLSDITDTILNLQDQMNAEKDAYNEIHDGLAQNVISVDEIDVQLNEIKTLYGNIR 355
jgi:EAT1b_0689 262 DQAENRREELM-VRIERLEFDHFEEDMQQLSSDIDQLFEAFRTEVDARQYVKKEFATIQERELQSSEIMNHLQTEMSRLV 340
BAH18095       258 QTLKGKLNLVE-PLIARLELDKAEEIIDEINDAIDDMVELVELEVKAKNNVELTKEEITDHLFHAKDTNYMIRTEIEYVK 336
B9DRR4         262 QEIREAIRSNA-SELVSLDLDRAREENSHIQERIDNMYALFEHEIKAFKVSAKHSKIIPSYLEHAKSNNDKLKEEMTRLS 340 Streptococcus...
A4VWI6         262 QNIRVSIRENT-ALIVSFDLDAAEAENEGIQAKIDHLYKVFNREIEANKEAVKISKNLPKFLEHVVQNTQLLDEESQRLN 340 Streptococcus...
4UXV_A         320 ESYRLTAGELGKQQAFEKRLDEIGKLLSSVKDKLDAEHVAYSLLVEEVASIEKQIEEVKKEHAEYRENLQALRKEELQAR 399 Bacillus subt...
CCZ23176       353 KNYILGDYTITIEDDYN-QFQSIVDDLAEITKIIETKDFSYIEMIDDFSRIVEQSKPYNDSLIKHIELAETLRIQEKRAL 431
CDE29004       353 TEFVIDEEEVVISKKYE-EFKQIQKDANDLIEQMESGHFAYANMLEHVENLYDRMMQHDTYLEEFEKQKEDIETKNQKTE 431
EDP11281       353 ERFGF-ENWTQRLQDTQTRLDVLNDMQRRLDKIVLDKQVPYTTILIAYKELAQSNAGFSKEVELMKEKLNNACSDEERAK 431
CDD51512       360 DRFGL-EDWTQRFMLANEQLTSLKKKRDSIVNLLKNDEQTSVELVHQYREYTQEVEEFHAQVKDMKQKLVGASSDESRAK 438
CDA33616       356 DRFGL-EDWTHRFALADEQMNNLKEACALIQKELDEDKMPRVDVIHYYREFANDIEEFKGQVNDMKTKLLNASSDESRAK 434
jgi:EAT1b_0689 341 SNYEINARVGEEFEQLERERATLTANVLDIEQALVAQMLPFSMIKSKVQEAKRSLDQFSAMHERFIEDTNSLRKEELEVR 420
BAH18095       337 DTYYIDEEAVQNVRGYDNEIQSLITVYDEILMETAKSSIRYTEVEDNLKYIESHVKVINEKQEKIQNYLMNLREDEQEAQ 416
B9DRR4         341 RKYILNENQASTVQGFEKEIEDVEKNVLELAKDFKGQEIPYSELQVVFEKNLKTLSAVESGQMEVFESIKNIENIEEDAR 420 Streptococcus...
A4VWI6         341 ATYLLADSKLSRINQLKARLESIEIVVTESVEDIENPQVAYSILEERLDHSLASLKEIEEEQLVLADYLKSQELSENTAR 420 Streptococcus...
4UXV_A         400 ETLSNLKKTISETARLLKTSNIPGIPSHIQEMLENAHHHIQETVNQLNELPLNMEEAGAHLKQAEDIVNRASRESEELVE 479 Bacillus subt...
CCZ23176       432 DELDNINIVLLEIKSEIRNKHLPMISESYQDYIDDSYQKADSILNFIRKRPIDLKSLSLQVDAARDVIYKLYDNVHNLIV 511
CDE29004       432 ELLENINIVLLEIKSEIKNEHLPLVNDSYRDYIADSYNKVEEIKRFKSHKPVVLNELCAKVEGARDVIYKLYDNVHNMIV 511
EDP11281       432 KQLIKLQLIINEIRVKMLKHRLPNVSAQYEKDLCKGEDMMHDVRDILEHSPLDVTQLNAKLREAIDFIYTLYNNVNNLVG 511
CDD51512       439 KQLIKLQLILNEVRLSAMTRHLPSISSSFNEDIKEGERLISRVRVVLEHSPLDVQTLNADLQDAIDFVYRLYNNANNLIG 518
CDA33616       435 KQLVKLQLILNEVRLNAATRNLPSVSSQFDEDIKQAEDMISRVQVVLSHSPLDVPTLNSDLQDAIDFVYKLYNNANNLIG 514
jgi:EAT1b_0689 421 HKLETWKKELSGHRRLLAKSAMPVVPNDLSNDLRQLQKGVQSLDEQFDKAPFNMTYIVGLSHDVEEMMDNFRDRVHALIR 500
BAH18095       417 HNVLHIQSKKEEVYRKLLASNLSSVPERFIIMKNEIDVEMREVHQLFNKRPMNVTQVRDKVNKVLTTMNTFESEAMEVLE 496
B9DRR4         421 KEADLYVTQLHMIKRFMEKRHLPGIPQDYLNVFFTTSTQLEALMDELSKGKINIEAVSRLRDVASASIANLEDYTYQVVE 500 Streptococcus...
A4VWI6         421 KKATLYINKLHTLKRYMEKRNLPGIPAEFLTNFFRTSDHVEALIAELDYKRINIEVVNRLLENATYDMNQLEELAYLIVQ 500 Streptococcus...
4UXV_A         480 QVILIEKIIQFGNRFRSQNHILSEQLKEAERRFYA-FDYDDSYEIAAAAVEKAAPGAVEKIKADI 543 Bacillus subtilis subsp. sub...
CCZ23176       512 TAEMVEDAIVFGNRYRSSFLEVNTELTKAELLYRN-GEYTKALSTAVDIIEKIKPDSYEMLVNkk 575
CDE29004       512 TAGMVEDAIVYANRYRSMFLEVNTELTKAEVLFRN-GEYRNALQVAVDILERLEPGKYEELikrk 575
EDP11281       512 MAIMVENTIVFGNRYRSSCPEIDSELTRCELCFRD-GQYTKALKIGIQCIEKMHPGAYEKLVNrk 575
CDD51512       519 VAIMVENAIVFGNRFRSSHPAIDSDLTRAELCFQN-GEYTRALKIAIQSIENMHPGVYEKLVark 582
CDA33616       515 VAVMVENAIVFGNRFRSTYPSMNTDLTRAELCFQN-GEYTRALKIAIQAIENLHPGTYEKLiark 578
jgi:EAT1b_0689 501 QVTYAEQLLQYANRFRRRDNEVHIALTLAENKFLH-GEYGTAVEIGERVLGRFDENGANEIRQRV 564
BAH18095       497 HALYAEKLIQYGNRYRKDSSDVNKDLIEAERLFSN-NRYKRAVEVAEAAIERVEPGVTERLEQNI 560
B9DRR4         501 NATLTEQLLQYSNRYRSFEAGVQNSFEIAMHLFEVeYDYQASFDEISYALETVEPGVTDRFVSSY 565 Streptococcus uberis 0140J
A4VWI6         501 NATLTEQLLQYSNRYRSFDESVQKAFNRSLSIFEKdFDYQAAFEEISFALETVEPGVTERFVRSY 565 Streptococcus suis 05ZYH33
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