Conserved Protein Domain Family
Mpo1-like

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pfam06127: Mpo1-like 
2-hydroxy-palmitic acid dioxygenase Mpo1-like
Budding yeast Mpo1 is a dioxygenase that catalyzes the alpha-oxidation of a 2-hydroxy fatty acid in an Fe2+-dependent manner. This entry also includes Mpo1 homologs from bacteria, fungi and plants. Their function is not clear.
Statistics
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PSSM-Id: 377609
Aligned: 64 rows
Threshold Bit Score: 56.0324
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9CA70         7 LLDLEKHFAFYGAYHSNPINIIIHTLFVWPNVFATLLFLYSTPpildhsqlgflksltfdgvlrldigftltvtyavfyi 86  thale cress
WP_011050334   8 ARPIERYFASYSDDHQNATNQQIHVLAVPAILWSVVALLWCIPvggswfssgvwaalsmfaawsyynrlsrp-------- 79  Xanthomonas
Q8F3Z0         1 MKSVETWLDEYGESHQNPINKNIHWICVPSIYFTVVGLLWAIPvpsiflsvpylnfatialvlalvfyirlsatl----- 75  Leptospira inte...
P25338         5 LLDLRSQLGFYKFYHHNPKNVLIHSIFVPTILFSGSCMLHRVKiyqsisltavlsvlfsifycllylp------------ 72  Saccharomyces c...
O13737         1 MTYLSRSYSFYAAYHSNPVNIKIHQVCIPLLLLTALVLLHNFVitlinsklqinvahlvglayqifyvtldpl------- 73  Schizosaccharom...
XP_015614300   8 LEHLERRYAFYAAYHSNPANVLVHAVCVWPILLTAMLPLRYAPplpllrfycplcrqylpvqlgfpvavalgayyalm-d 86 
Q8EH76         1 MKSAVEQLSTYKSVHLNPRNIQTHFIGIPLIIWSAFLLFATIRiplgdadnvnlgmilaigimlyylrlh---------- 70  Shewanella onei...
Q9I6L4         1 MKTLVDHLAQYAAYHRDRRNIFSHFIGIPMIVLSIAVLLARPAlgfglspalllalaaalfylrldlrf----------- 69  Pseudomonas aer...
WP_003251951   1 MKTLVDHLSQYANYHRDPRNIATHFVGIPMIVLAVTILLSRPGweiagmwlspalvaaaasvwfylrldlr--------- 71  Pseudomonas
Q8XRM5        12 MRPLSDHLSSYAAYHQDGRNIATHFFGIPVIVVAVAVLFSRPVlgllpggvavtpallllvavtvfylrldv-------- 83  Ralstonia solan...
Q9CA70        87 cldkksgvlaallcfscwigssflaarlghsltL---KVGVASQLLCWTGQFLGHGLFEKRAPALLDNLLQAFLMGPFFV 163 thale cress
WP_011050334  80 -----lglgmlgiffffgclcrliegrtglgglF---TTALTVFVLAWIAQFVGHK-IEGRKPSFLTD-LTYLLIGPIWV 149 Xanthomonas
Q8F3Z0        76 --afgmlvlsslmmyliillqrtllpimigsysYgilELSITIFVLAWIGQFIGHK-IEGKKPSFFKD-LQFLMIGPIWL 151 Leptospira inte...
P25338        73 ---------tgllagvlllllnlalidhrvdltF---KQELGLFTIGWIFQFVGHGVFEKRRPALIDNLVQSLVLAPYFI 140 Saccharomyces c...
O13737        74 ----dgllyspvlylfsyilpsklftifsrslvN---RSAAVVHVICWILQFIGHGVFEKRKPALLDNLIQSLFIAPLFA 146 Schizosaccharom...
XP_015614300  87 rragaaaaalcvagwaagtlladaaglwtfrdaW---RPLLTAQAVLWSAQFFSHAFFEKRRPALVDGPVQAVVTAPLFV 163
Q8EH76        71 ------aklalglalflapviyttelvahsenaF---GLAITVFIVGWIFQLIGHR-YEKAKPAFVDD-LNQLLIGPFFL 139 Shewanella onei...
Q9I6L4        70 -------gvamtallaltvwgaaqlaagttaawL---GWGVGLFVVGWIIQFVGHY-YEGRKPAFVDD-LSGLIVGPLFV 137 Pseudomonas aer...
WP_003251951  72 ------fglvmglllglclwvgealavqsttlwL---GAGLGAFVVGWIIQFIGHY-YEGRKPAFVDD-VSGLIIGPLFV 140 Pseudomonas
Q8XRM5        84 -----vfglamlgligmavwvghhvaahstvawL---SVGLGLFVIGWIVQFVGHY-YEGRKPAFVDD-LAGLVIGPLFL 153 Ralstonia solan...
Q9CA70       164 LLEVLQSV 171 thale cress
WP_011050334 150 LAKAYRQL 157 Xanthomonas
Q8F3Z0       152 LGFIYKKM 159 Leptospira interrogans
P25338       141 MFEFLFKL 148 Saccharomyces cerevisiae S288C
O13737       147 FLETGPFV 154 Schizosaccharomyces pombe 972h-
XP_015614300 164 FIEVLHRL 171
Q8EH76       140 MAEVYFML 147 Shewanella oneidensis
Q9I6L4       138 LAELAFLL 145 Pseudomonas aeruginosa
WP_003251951 141 VAEAAFML 148 Pseudomonas
Q8XRM5       154 LAETVFAM 161 Ralstonia solanacearum
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