6F0X,4XGU,5XMI,5WC1,4L15,5W0T,2X8A,6OMB,5G4G,5MP9,6EF1,5A5B,5EQT,3H4M,6HEC,2QZ4,2R65,6GCN,6SH3,6WGG,7JK2,3U5Z,1SXJ,2CHG,6VVO,7KSM,6U5Z,3M6A,6BLB,1IN5


Conserved Protein Domain Family
AAA

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pfam00004: AAA 
ATPase family associated with various cellular activities (AAA)
AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Statistics
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PSSM-Id: 459627
Aligned: 207 rows
Threshold Bit Score: 56.8329
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6F0X_E  175 VLLHGPPGTGKTSLCKALAQKLT----IRlssryrygqL-IEINSHSLF-SK---------------WFSESGKLVTKMF 233  human
P33760  479 LLHSTTNNVGKATMVRFASKYLG----IH---------L-LEIDCLSLTsNS---------------RQLDSTSKIIGYI 529  Saccharomyces cerev...
P36966  473 LLHSAKRGVGKSTVLRSVAAQCG----IS---------V-FEISCFGLI--------------------GDNEAQTLGTL 518  Yarrowia lipolytica...
P46463  519 SLLFGTSGSGKSLVISQVAQIV-----TNkg------hF-VKLLNCDKI-------------------MSESYNNLRGIF 567  Komagataella pastoris
O43933  595 LLLTGGKGSGKSTLAKAICKEAFdkldAH---------V-ERVDCKALR--------------------GKRLENIQKTL 644  human
O74941  375 IYINGPKGCGKSNLVHSLFDY-YslnsIY---------FqMIVSCSEIDrSS--------------------FAKFQSFW 424  Schizosaccharomyces...
P54777  466 VLLQGPPGSGKTTAVTAACSRLG----LH---------L-LKVPCSSLC--------------------ADSSRTVETKL 511  Norway rat
O13764  425 FLLHGNPFTGKTKAVEEVASLFS----AP---------V-FTISSYEFA--------------------DATADHLEAKL 470  Schizosaccharomyces...
P41653 1373 ILLIGPMGTGRSYLVKSLAADSY----VP---------L-IRISLKKLWyGEyldypleriptefdpFVKDKMEDFHITL 1438 Japanese black pine
P09975 1400 ILLIGPIETGRSYLIKNLAAESY----VP---------L-FKISINKLLyNKpdvit-----eswmnILIESLRRLNLTL 1460 liverwort
6F0X_E  234 QKi-QDLIddkdAlVFVLIDQVESLTAARnacragte---psdairvVNAVLTQIDQIKRH-----SNVVILTTSNITEK 304  human
P33760  530 RAkcENVLpyasP-AVIFLAHLDSILLDVnanqdp-------eaiklQKSINFEMSKLLDDftfkfPGTTFVGSVNNIDN 601  Saccharomyces cerev...
P36966  519 RA--KLDRaygcSpCVVVLQHLESIAKKSdqdgk---------degiVSKLVDVLADYSG------HGVLLAATSNDPDK 581  Yarrowia lipolytica...
P46463  568 EDi-FSEVswkaP-SLLILEDLDSLIPAEqehsds------sqsrqlSEYFISKLSAQTINr----D-ITILASSKSKES 634  Komagataella pastoris
O43933  645 EVa-FSEAvwmqP-SVVLLDDLDLIAGLPavpehehsp-davqsqrlAHALNDMIKEFISMg----SLVALIATSQSQQS 717  human
O74941  425 NNv-FIQAeryeP-SIIYLDDVHCLISSSnengelg-----fveereIAFLQHQIINLKRK-----RKIIFIGFGEEFLT 492  Schizosaccharomyces...
P54777  512 QTt-FSRArrcrP-VVLLLTALDLLGRDRdglge---------darvVATLRHLLLDEDPLsr--cPPLMVVATTSRVQD 578  Norway rat
O13764  471 DM--FVQNvvksPcAIIFVKDLDVLSISSdegniv-------pgsksIQILLSKIDLVKSPq----GRYIVIGTCHSIEK 537  Schizosaccharomyces...
P41653 1439 ELa-KRMS----P-CIIWIPNIHELNLNDatnylfgfgftdlflsvlMNNLFRFRDGEKDSm----RNILVIASTHIPQR 1508 Japanese black pine
P09975 1461 DFa-KKMS----P-CIIWIQNIHQLNVNRltqnve------sdptflLGILLKYFQTDFSKtk--kNNIIVIGSTHLPKK 1526 liverwort
6F0X_E  305 IDVAFV--DRADIKQYIGP 321  human
P33760  602 VPSSFRshMRFEILVPVPS 620  Saccharomyces cerevisiae S288C
P36966  582 ISEAIR--SRFQFEIEIGV 598  Yarrowia lipolytica CLIB122
P46463  635 LNSLIFttHLIEHDFQLRA 653  Komagataella pastoris
O43933  718 LHPLLV--SAQGVHIFQCV 734  human
O74941  493 FSENLVlpLLFQIKIALPS 511  Schizosaccharomyces pombe 972h-
P54777  579 LPTDVR--TAFPHELEVPV 595  Norway rat
O13764  538 IPYEIL--SESFFELKFSE 554  Schizosaccharomyces pombe 972h-
P41653 1509 VDPALIapNRLDRSINIRM 1527 Japanese black pine
P09975 1527 VDPALIspNRLDKIINVRL 1545 liverwort
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