2RKO,2X8A,3WHK,3CF0,5G4F,5GJQ,3D8B,5GJQ,5T0G,5GJQ,2QZ4,3J94,4XGU,1HQC,3PVS,1IN4,2CHG,4W5W,1SXJ,3U5Z,5UDB,4XGC


Conserved Protein Domain Family
AAA

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pfam00004: AAA 
Click on image for an interactive view with Cn3D
ATPase family associated with various cellular activities (AAA)
AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Statistics
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PSSM-Id: 333757
View PSSM: pfam00004
Aligned: 228 rows
Threshold Bit Score: 55.6706
Threshold Setting Gi: 1708857
Created: 13-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2RKO_A   63 ILLYGPPGTGKSYLAKAVATEANST---FFSVSSSDLV-SKWMGESEKLVKQLFAMa-RENK----P-SIIFIDEVDALT 132  baker's yeast
P96281  250 VLVSGPAGVGKATLVRAVCDG--RR---LVTLDGPEIGa-lAAGDRVKAVASAVQAv-RHEG------GVLLITDADALL 316  Mycobacterium tuber...
P33760  479 LLHSTTNNVGKATMVRFASKYLGIH---LLEIDCLSLTsNSRQLDSTSKIIGYIRAkcENVLpyasP-AVIFLAHLDSIL 554  Saccharomyces cerev...
P36966  473 LLHSAKRGVGKSTVLRSVAAQCGIS---VFEISCFGLI-----GDNEAQTLGTLRA--KLDRaygcSpCVVVLQHLESIA 542  Yarrowia lipolytica...
P46463  519 SLLFGTSGSGKSLVISQVAQIV-TNkghFVKLLNCDKI----MSESYNNLRGIFEDi-FSEVswkaP-SLLILEDLDSLI 591  Komagataella pastoris
O83350  346 YLISGPIGTGKSFMVSAFAGEIGIP---MVRLCNFQAT---QPGITQSNLEKTLNIl-KALT----P-VAVMVDEADAVF 413  Treponema pallidum
Q57264  143 MLILGVPGCGKSLIAKTTSRLWGLP---LLRLDMGRVYdGSMVGRSEANLRNALKTa-ESIS----P-AILFIDELDKAF 213  Synechocystis
O78439  278 LLLVGIQGTGKSLTAKSIANEWNLP---LLKLDVGRLF-GGIIGESEARVRQMIQFa-ETIS----P-CILWIDEIDKAF 347  Guillardia theta
P49541  262 LLLIGIQGTGKSLTAKAIATEWQLP---LLKLDVGRLF-GGIVGESESRLRQMIDVa-ETLS----P-CILWIDEMDKAF 331  Odontella sinensis
Q55174  262 LLLAGIQGTGKSLTAKAIAHHWHLP---LLRLDVGRLF-GGLVGESEARTRQMINLa-EALA----P-CVFWIDEIDKAF 331  Synechocystis sp. P...
2RKO_A  133 GTRgegese---asrriKTELLVQMNGVGNDs----QGVLVLGATNIPWQLDSAIRr--RFERRIYIPL 192  baker's yeast
P96281  317 PAAae----------pvASLILSELRTAVAT-----AGVVLIATSARPDQLDARLRspeLCDRELGLPL 370  Mycobacterium tuberculosis
P33760  555 LDVnanqdp---eaiklQKSINFEMSKLLDDftfkfPGTTFVGSVNNIDNVPSSFRshmRFEILVPVPS 620  Saccharomyces cerevisiae S288c
P36966  543 KKSdqdgk-----degiVSKLVDVLADYSG------HGVLLAATSNDPDKISEAIRs--RFQFEIEIGV 598  Yarrowia lipolytica CLIB122
P46463  592 PAEqehsds--sqsrqlSEYFISKLSAQTINr----D-ITILASSKSKESLNSLIFtthLIEHDFQLRA 653  Komagataella pastoris
O83350  414 GRRnapag-----esriFAQIAGFMGNTQHR-----GNIIWFLITSRPDLLPIDLKrqgRAEEHLALFY 472  Treponema pallidum
Q57264  214 AGGagsgdsdggtssriFGSFLTWMQEKTS-------PVFVMATANRVDRLPGEFLrkgRFDEIFFVDL 275  Synechocystis
O78439  348 TGSnfnnds--gttkrvFGTFITWLSEKKS-------PVFVVATANNIDSLPPELLrkgRFDEVFFIGL 407  Guillardia theta
P49541  332 SNNdsrgds--gtsnrvLATFISWLSEKTK-------PVFVVATANNVDLLPLEIIrkgRFDEIFFLDL 391  Odontella sinensis
Q55174  332 GSMdshgdg--gttsrvFGAFITWLAEKTS-------PVFVVATANNVQSLPPELLrkgRFDEIFFVGL 391  Synechocystis sp. PCC 6803
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