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lasso peptide biosynthesis PqqD family chaperone Members of this family are homologs of PqqD, a chaperone that binds RiPP peptide precursors for their modification into bioactive natural products. By context, this set is involved in the biosynthesis of threaded-lasso peptides. This model focuses on lasso peptide systems from Actinobacteria. Similar systems, with different subfamilies of PqqD-related peptides, occur in lasso peptide systems in other lineages. A characterized example is LarB1 from the lariatin system of Rhodococcus jostii. |
Jiyao W et al.(2023). "The conserved domain database in 2023.",