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    SREBF2 sterol regulatory element binding transcription factor 2 [ Tursiops truncatus (common bottlenose dolphin) ]

    Gene ID: 101324604, updated on 8-Mar-2024

    Summary

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    Gene symbol
    SREBF2
    Gene description
    sterol regulatory element binding transcription factor 2
    See related
    EnsemblRapid:ENSTTRG00000017350
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Tursiops truncatus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Tursiops
    Orthologs
    human mouse all
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    Genomic context

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    See SREBF2 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    102 current mTurTru1.mat.Y (GCF_011762595.1) 11 NC_047044.1 (7088813..7149340, complement)
    101 previous assembly NIST Tur_tru v1 (GCF_001922835.1) Unplaced Scaffold NW_017842383.1 (2878471..2906936)

    Chromosome 11 - NC_047044.1Genomic Context describing neighboring genes Neighboring gene TNF receptor superfamily member 13C Neighboring gene shisa family member 8 Neighboring gene coiled-coil domain containing 134 Neighboring gene meiotic double-stranded break formation protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of cholesterol storage IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sterol regulatory element-binding protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Tursiops truncatus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mTurTru1.mat.Y Primary Assembly

    Genomic

    1. NC_047044.1 Reference mTurTru1.mat.Y Primary Assembly

      Range
      7088813..7149340 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_033865935.1 → XP_033721826.1  sterol regulatory element-binding protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A6J3S5K2
      Related
      ENSTTRP00000016443.2, ENSTTRT00000017351.2
      Conserved Domains (1) summary
      cd18922
      Location:320 → 396
      bHLHzip_SREBP2; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in sterol regulatory element-binding protein 2 (SREBP2) and similar proteins

    2. XM_033865936.1 → XP_033721827.1  sterol regulatory element-binding protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A6J3S4G8
      Conserved Domains (1) summary
      cd18922
      Location:166 → 242
      bHLHzip_SREBP2; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in sterol regulatory element-binding protein 2 (SREBP2) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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