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malY negative regulator of MalT activity/cystathionine beta-lyase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945937, updated on 19-Sep-2024

Summary

Official Symbol
malY
Official Full Name
negative regulator of MalT activity/cystathionine beta-lyase
Primary source
ECOCYC:EG10564
Locus tag
b1622
See related
ASAP:ABE-0005432
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1617
Summary
MalY is a bifunctional protein with a regulatory as well as an enzymatic function. [More information is available at EcoCyc: EG10564].
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Genomic context

Sequence:
NC_000913.3 (1700957..1702129)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional repressor MalI Neighboring gene PTS enzyme IIBC component MalX Neighboring gene adenosine deaminase Neighboring gene putative oxidoreductase YdgJ

Pathways from PubChem

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA-binding transcription factor binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables L-cysteine desulfhydrase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables cysteine-S-conjugate beta-lyase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables cysteine-S-conjugate beta-lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
enables pyridoxal phosphate binding IDA
Inferred from Direct Assay
more info
PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 
enables pyridoxal phosphate binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
involved_in biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in methionine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
negative regulator of MalT activity/cystathionine beta-lyase
NP_416139.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1700957..1702129
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416139.1 negative regulator of MalT activity/cystathionine beta-lyase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416139.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7EDP5
    Conserved Domains (1) summary
    COG1168
    Location:1390
    MalY; Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism, General function prediction only]