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ipaA invasion protein [ Shigella flexneri 5a str. M90T ]

Gene ID: 876595, discontinued on 19-Aug-2020
  • This record was discontinued.

Summary

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Gene symbol
ipaA
Gene description
invasion protein
Locus tag
pWR501_0133
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Shigella flexneri 5a str. M90T (strain: M90T, serotype: 5a)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Also known as
S0133
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Genomic context

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Location:
plasmid: virulence plasmid pWR501
Sequence:
NC_002698.1 (100203..102104, complement)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002698.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Shigella IpaA Binding to Talin Stimulates Filopodial Capture and Cell Adhesion.
    Title: Shigella IpaA Binding to Talin Stimulates Filopodial Capture and Cell Adhesion.
  2. IpaA targets beta1 integrins and rho to promote actin cytoskeleton rearrangements necessary for Shigella entry
    Title: IpaA targets beta1 integrins and rho to promote actin cytoskeleton rearrangements necessary for Shigella entry.
  3. Invasin IpaA subverts vinculin's functions. Shigella flexneri utilizes a remarkable level of molecular mimicry of the talin-vinculin interaction to activate vinculin using invasin IpaA.
    Title: Shigella applies molecular mimicry to subvert vinculin and invade host cells.
Submit: New GeneRIF Correction

General protein information

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Preferred Names
invasion protein
NP_085287.1
  • residues 1 to 633 of 633 are 100.00 pct identical to residues 1 to 633 of 633 of product encoded by GenBank Accession Number X17628 invasion plasmid antigen (AA 1-633( [Shigella flexneri]

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002698.1 Reference assembly

    Range
    100203..102104 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_085287.1 invasion protein [Shigella flexneri 5a str. M90T]

    Status: PROVISIONAL

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Research Materials