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LEJ2 Cystathionine beta-synthase (CBS) family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 829844, updated on 18-Sep-2024

Summary

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Official Symbol
LEJ2
Official Full Name
Cystathionine beta-synthase (CBS) family protein
Primary source
TAIR:AT4G36910
Locus tag
AT4G36910
See related
Araport:AT4G36910
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AP22.61; AP22_61; CBS domain containing protein 1; CBSX1; CDCP2; CYSTATHIONE [BETA]-SYNTHASE DOMAIN-CONTAINING PROTEIN 2; LOSS OF THE TIMING OF ET AND JA BIOSYNTHESIS 2
Summary
Encodes a single cystathionine beta-synthase domain-containing protein. Modulates development by regulating the thioredoxin system.
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Genomic context

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Location:
chromosome: 4
Exon count:
8
Sequence:
Chromosome: 4; NC_003075.7 (17390626..17393479, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Single cystathionine β-synthase domain-containing proteins modulate development by regulating the thioredoxin system in Arabidopsis. Yoo KS, et al. Plant Cell, 2011 Oct. PMID 22021414, Free PMC Article
  2. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
  3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
  4. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Two CBS domain-containing proteins, CBSX1 and CBSX2, are localized to the chloroplast, where they activate all four thioredoxins in the ferredoxin-thioredoxin system in Arabidopsis thaliana.
    Title: Single cystathionine β-synthase domain-containing proteins modulate development by regulating the thioredoxin system in Arabidopsis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_119855.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell redox homeostasis IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Cystathionine beta-synthase (CBS) family protein
NP_195409.1
  • LOSS OF THE TIMING OF ET AND JA BIOSYNTHESIS 2 (LEJ2); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cystathionine beta-synthase, core (InterPro:IPR000644); BEST Arabidopsis thaliana protein match is: Cystathionine beta-synthase (CBS) family protein (TAIR:AT4G34120.1); Has 8411 Blast hits to 7757 proteins in 1885 species: Archae - 1245; Bacteria - 5956; Metazoa - 278; Fungi - 143; Plants - 147; Viruses - 0; Other Eukaryotes - 642 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    17390626..17393479 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_119855.4 → NP_195409.1  Cystathionine beta-synthase (CBS) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_195409.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O23193
    UniProtKB/TrEMBL
    A0A654FW62
    Conserved Domains (2) summary
    COG0517
    Location:77 → 222
    CBS; CBS domain [Signal transduction mechanisms]
    cd02205
    Location:85 → 224
    CBS_pair; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O23193.2

Gene LinkOut

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