AP1G1 adaptor related protein complex 1 subunit gamma 1 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: AP1G1provided by VGNC
Official Full Name: adaptor related protein complex 1 subunit gamma 1provided by VGNC
Primary source: VGNC:VGNC:25977
See related: BGD:BT26510; Ensembl:ENSBTAG00000002769
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 26

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	18	NC_037345.1 (39248017..39350493)

Chromosome 18 - NC_037345.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Cytosolic AP-1 is recruited onto the trans- Golgi network via binding to Arf-1.GTP, cargo-sorting signals and phosphoinositides, where it orchestrates the assembly of clathrin-coated vesicular carriers that transport cargo molecules to endosomes.
Title: Cargo-sorting signals promote polymerization of adaptor protein-1 in an Arf-1.GTP-independent manner.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables clathrin adaptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in Golgi to vacuole transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in intracellular protein transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in receptor-mediated endocytosis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of AP-1 adaptor complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info	PubMed
part_of membrane coat	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: AP-1 complex subunit gamma-1

Names: adaptor related protein complex 1 gamma 1 subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001191436.1 → NP_001178365.1 AP-1 complex subunit gamma-1

See identical proteins and their annotated locations for NP_001178365.1

Status: PROVISIONAL

Source sequence(s)

NKLS02000018

UniProtKB/TrEMBL

A0A3Q1M952, F1MF68

Related

ENSBTAP00000066662.1, ENSBTAT00000073132.2

Conserved Domains (4) summary

smart00809
Location:712 → 820

Alpha_adaptinC2; Adaptin C-terminal domain

pfam05109
Location:593 → 711

Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

sd00044
Location:142 → 163

HEAT; HEAT repeat [structural motif]

pfam01602
Location:23 → 577

Adaptin_N; Adaptin N terminal region

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

Range

39248017..39350493

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_059876569.1 → XP_059732552.1 AP-1 complex subunit gamma-1 isoform X1

UniProtKB/TrEMBL

F1MF68

Related

ENSBTAP00000095741.1, ENSBTAT00000113139.1
XM_005218489.5 → XP_005218546.1 AP-1 complex subunit gamma-1 isoform X1

See identical proteins and their annotated locations for XP_005218546.1

UniProtKB/TrEMBL

F1MF68

Conserved Domains (4) summary

smart00809
Location:709 → 817

Alpha_adaptinC2; Adaptin C-terminal domain

sd00044
Location:142 → 163

HEAT; HEAT repeat [structural motif]

pfam01602
Location:23 → 574

Adaptin_N; Adaptin N terminal region

cl25496
Location:590 → 708

Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
XM_059876570.1 → XP_059732553.1 AP-1 complex subunit gamma-1 isoform X1

UniProtKB/TrEMBL

F1MF68

Related

ENSBTAP00000003599.6, ENSBTAT00000003599.7
XM_059876571.1 → XP_059732554.1 AP-1 complex subunit gamma-1 isoform X2