PSMB8 proteasome 20S subunit beta 8 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: PSMB8provided by VGNC
Official Full Name: proteasome 20S subunit beta 8provided by VGNC
Primary source: VGNC:VGNC:33452
See related: BGD:BT10247; Ensembl:ENSBTAG00000003039
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: LMP7
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 23

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	23	NC_037350.1 (7173032..7176410, complement)

Chromosome 23 - NC_037350.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:: NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

MARC_5881-5882:997299388:1 (e-PCR)
- UniSTS:269597

PSMB8 (e-PCR)
- UniSTS:278977

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables threonine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in proteolysis involved in protein catabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of proteasome core complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: proteasome subunit beta type-8

Names: large multifunctional protease 7; macropain; proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7); proteasome subunit LMP7; proteasome subunit beta 8; proteasome subunit beta-5i; proteasome subunit, beta type 8

NP_001035570.1

EC 3.4.25.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001040480.2 → NP_001035570.1 proteasome subunit beta type-8

See identical proteins and their annotated locations for NP_001035570.1

Status: PROVISIONAL

Source sequence(s)

BC102170

UniProtKB/TrEMBL

A0AAF6YKP0

Related

ENSBTAP00000003955.6, ENSBTAT00000003955.7

Conserved Domains (2) summary

PTZ00488
Location:37 → 271

PTZ00488; Proteasome subunit beta type-5; Provisional

cd03761
Location:73 → 260

proteasome_beta_type_5; proteasome beta type-5 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...