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    LDV_gp1 polyprotein 1a;polyprotein 1ab [ Lactate dehydrogenase-elevating virus ]

    Gene ID: 4783122, updated on 18-Aug-2023

    Summary

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    Gene symbol
    LDV_gp1
    Gene description
    polyprotein 1a;polyprotein 1ab
    Locus tag
    LDV_gp1
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Lactate dehydrogenase-elevating virus (strain: Plagemann)
    Lineage
    Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Nidovirales; Arteriviridae
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    Genomic context

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    Sequence:
    NC_001639.1 (157..11006)

    NC_001639.1Genomic Context describing neighboring genes Neighboring gene 1aTF polyprotein Neighboring gene E protein Neighboring gene glycoprotein GP2 Neighboring gene glycoprotein GP3 Neighboring gene glycoprotein GP4 Neighboring gene major structural glycoprotein GP5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001639.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence of the genome of lactate dehydrogenase-elevating virus: heterogenicity between strains P and C. Palmer GA, et al. Virology, 1995 Jun 1. PMID 7778295
    2. The envelope proteins of lactate dehydrogenase-elevating virus and their membrane topography. Faaberg KS, et al. Virology, 1995 Oct 1. PMID 7571421

    GeneRIFs: Gene References Into Functions

    General gene information

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    Miscellaneous features

    • Loc: 6763-6850 pseudoknot; ribosomal frameshift region; frameshift [minus 1] at orf1a/1b junction

    General protein information

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    Preferred Names
    polyprotein 1a;polyprotein 1ab
    NP_042572.1
    • ORF 1a; includes two papain-like cysteine proteases and serine protease
    YP_001008394.2
    • -1 translational frameshift

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001639.1 Reference assembly

      Range
      157..11006
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_001008394.2 polyprotein 1ab [Lactate dehydrogenase-elevating virus]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q83017, Q83018, Q83024, Q83025, Q86716
      Conserved Domains (9) summary
      pfam05412
      Location:381 → 486
      Peptidase_C33; Equine arterivirus Nsp2-type cysteine proteinase
      pfam05410
      Location:57 → 162
      Peptidase_C31; Porcine arterivirus-type cysteine proteinase alpha
      pfam05411
      Location:257 → 380
      Peptidase_C32; Equine arteritis virus putative proteinase
      pfam05579
      Location:1420 → 1715
      Peptidase_S32; Equine arteritis virus serine endopeptidase S32
      pfam01443
      Location:2990 → 3208
      Viral_helicase1; Viral (Superfamily 1) RNA helicase
      pfam12581
      Location:3585 → 3616
      DUF3756; Protein of unknown function (DUF3756)
      pfam16749
      Location:1896 → 2025
      Arteri_nsp7a; Arterivirus nonstructural protein 7 alpha
      cl02808
      Location:2539 → 2750
      RT_like; RT_like: Reverse transcriptase (RT, RNA-dependent DNA polymerase)_like family. An RT gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. RTs occur in a variety of mobile elements, including retrotransposons, ...
      cl22977
      Location:3171 → 3214
      UvrD_C_2; UvrD-like helicase C-terminal domain

    2. NP_042572.1 polyprotein 1a [Lactate dehydrogenase-elevating virus]

      See identical proteins and their annotated locations for NP_042572.1

      Status: PROVISIONAL

      Conserved Domains (5) summary
      pfam05412
      Location:381 → 486
      Peptidase_C33; Equine arterivirus Nsp2-type cysteine proteinase
      pfam05410
      Location:57 → 162
      Peptidase_C31; Porcine arterivirus-type cysteine proteinase alpha
      pfam05411
      Location:257 → 380
      Peptidase_C32; Equine arteritis virus putative proteinase
      pfam05579
      Location:1420 → 1715
      Peptidase_S32; Equine arteritis virus serine endopeptidase S32
      pfam16749
      Location:1896 → 2025
      Arteri_nsp7a; Arterivirus nonstructural protein 7 alpha
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    2210400A.1

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