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    sec24 COPII cargo receptor Sec24/Sfb2 subunit [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541601, updated on 13-Mar-2024

    Summary

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    Gene symbol
    sec24
    Gene description
    COPII cargo receptor Sec24/Sfb2 subunit
    Primary source
    PomBase:SPAC22F8.08
    Locus tag
    SPAC22F8.08
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    sfb2
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    Genomic context

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    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (4799541..4802652)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene tRNA-Ala Neighboring gene replication termination factor Rtf1 Neighboring gene putative rRNA processing protein Rrp16 Neighboring gene putative U2 snRNP-associated protein Sap145 Neighboring gene miscRNA Neighboring gene phosphoinositide phospholipase C Plc1 Neighboring gene small histone ubiquitination factor Shf1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The actomyosin ring recruits early secretory compartments to the division site in fission yeast. Vjestica A, et al. Mol Biol Cell, 2008 Mar. PMID 18184749, Free PMC Article
    2. Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways. Das J, et al. Sci Signal, 2013 May 21. PMID 23695164, Free PMC Article
    3. Systematic analysis reveals the prevalence and principles of bypassable gene essentiality. Li J, et al. Nat Commun, 2019 Mar 1. PMID 30824696, Free PMC Article
    4. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables SNARE binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in COPII-coated vesicle cargo loading IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular protein transport IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of COPII vesicle coat IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cis-Golgi network IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in endoplasmic reticulum exit site IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum exit site IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in equatorial cell cortex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    COPII cargo receptor Sec24/Sfb2 subunit

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4799541..4802652
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020159.2 → NP_594731.1  COPII cargo receptor Sec24/Sfb2 subunit [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594731.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P78800, Q9UUI5
      Conserved Domains (6) summary
      COG5028
      Location:1 → 926
      COG5028; Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion]
      cd01479
      Location:327 → 570
      Sec24-like; Sec24-like: Protein and membrane traffic in eukaryotes is mediated by at least in part by the budding and fusion of intracellular transport vesicles that selectively carry cargo proteins and lipids from donor to acceptor organelles. The two main classes ...
      pfam00626
      Location:792 → 867
      Gelsolin; Gelsolin repeat
      pfam04810
      Location:253 → 290
      zf-Sec23_Sec24; Sec23/Sec24 zinc finger
      pfam04815
      Location:669 → 767
      Sec23_helical; Sec23/Sec24 helical domain
      pfam08033
      Location:572 → 654
      Sec23_BS; Sec23/Sec24 beta-sandwich domain
    Nucleotide Protein
    Heading Accession and Version

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