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    AI987944 expressed sequence AI987944 [ Mus musculus (house mouse) ]

    Gene ID: 233168, updated on 8-Feb-2024

    Summary

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    Official Symbol
    AI987944provided by MGI
    Official Full Name
    expressed sequence AI987944provided by MGI
    Primary source
    MGI:MGI:2142079
    See related
    Ensembl:ENSMUSG00000056383 AllianceGenome:MGI:2142079
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Is expressed in dorsal root ganglion and trigeminal ganglion. Orthologous to human ZNF101 (zinc finger protein 101). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in testis adult (RPKM 3.3), bladder adult (RPKM 2.9) and 28 other tissues See more
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    Genomic context

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    Location:
    7 B3; 7 28.25 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (41022347..41042772, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (41372923..41393379, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene baculoviral IAP repeat-containing 4 pseudogene Neighboring gene zinc finger, MYND-type containing 8 pseudogene 2 Neighboring gene STARR-positive B cell enhancer ABC_E3715 Neighboring gene predicted gene 17102 Neighboring gene vomeronasal 2, receptor 57 Neighboring gene STARR-seq mESC enhancer starr_18727 Neighboring gene STARR-seq mESC enhancer starr_18728

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    2. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC60751, MGC117553

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC233168

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001199330.2 → NP_001186259.1  uncharacterized protein LOC233168 isoform 2

      See identical proteins and their annotated locations for NP_001186259.1

      Status: VALIDATED

      Source sequence(s)
      AC137152
      Consensus CDS
      CCDS85272.1
      UniProtKB/TrEMBL
      Q4KL68
      Related
      ENSMUSP00000145621.2, ENSMUST00000205338.2
      Conserved Domains (3) summary
      COG5048
      Location:48 → 402
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:264 → 284
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:1 → 41
      KRAB; KRAB box

    2. NM_001421750.1 → NP_001408679.1  uncharacterized protein LOC233168 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC137152
      UniProtKB/TrEMBL
      Q4KL68

    3. NM_001421752.1 → NP_001408681.1  uncharacterized protein LOC233168 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC137152
      UniProtKB/TrEMBL
      Q4KL68

    4. NM_001421753.1 → NP_001408682.1  uncharacterized protein LOC233168 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC137152

    5. NM_001421754.1 → NP_001408683.1  uncharacterized protein LOC233168 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC137152

    6. NM_001421755.1 → NP_001408684.1  uncharacterized protein LOC233168 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC137152
      UniProtKB/TrEMBL
      A0A0U1RNH4

    7. NM_001421756.1 → NP_001408685.1  uncharacterized protein LOC233168 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC137152

    8. NM_001421757.1 → NP_001408686.1  uncharacterized protein LOC233168 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC137152

    9. NM_183167.5 → NP_898990.1  uncharacterized protein LOC233168 isoform 1

      See identical proteins and their annotated locations for NP_898990.1

      Status: VALIDATED

      Source sequence(s)
      AC137152
      Consensus CDS
      CCDS39920.1
      UniProtKB/TrEMBL
      Q7TPX5
      Related
      ENSMUSP00000071708.8, ENSMUST00000071804.10
      Conserved Domains (5) summary
      smart00349
      Location:4 → 45
      KRAB; krueppel associated box
      COG5048
      Location:51 → 405
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:267 → 287
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:4 → 43
      KRAB; KRAB box
      pfam13465
      Location:307 → 332
      zf-H2C2_2; Zinc-finger double domain

    RNA

    1. NR_185325.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC137152

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      41022347..41042772 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011250853.3 → XP_011249155.1  uncharacterized protein LOC233168 isoform X1

      See identical proteins and their annotated locations for XP_011249155.1

      UniProtKB/TrEMBL
      Q4KL68
      Conserved Domains (3) summary
      COG5048
      Location:48 → 402
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:264 → 284
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:1 → 41
      KRAB; KRAB box
    Nucleotide Protein Strain
    Heading Accession and Version

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