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    TMSB4 thymosin beta 4, X-linked [ Bos taurus (cattle) ]

    Gene ID: 781334, updated on 7-Jul-2022

    Summary

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    Gene symbol
    TMSB4
    Gene description
    thymosin beta 4, X-linked
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    TMSB4X
    Annotation information
    not in current annotation release
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    Genomic context

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    Location:
    chromosome: 1

    Bibliography

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    Related articles in PubMed

    1. How a single residue in individual β-thymosin/WH2 domains controls their functions in actin assembly. Didry D, et al. EMBO J, 2012 Feb 15. PMID 22193718, Free PMC Article
    2. Coupling of folding and binding of thymosin beta4 upon interaction with monomeric actin monitored by nuclear magnetic resonance. Domanski M, et al. J Biol Chem, 2004 May 28. PMID 15039431
    3. Thymosin beta 4 sulfoxide is an anti-inflammatory agent generated by monocytes in the presence of glucocorticoids. Young JD, et al. Nat Med, 1999 Dec. PMID 10581087
    4. Conformation of thymosin beta 4 in water determined by NMR spectroscopy. Czisch M, et al. Eur J Biochem, 1993 Dec 1. PMID 8269922
    5. Complete amino acid sequence of bovine thymosin beta 4: a thymic hormone that induces terminal deoxynucleotidyl transferase activity in thymocyte populations. Low TL, et al. Proc Natl Acad Sci U S A, 1981 Feb. PMID 6940133, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. TMSB4 and/or TMSB10 ovarian expression patterns suggest that these two thymosins may be involved in cumulus modifications during maturation.
      Title: Thymosins β-4 and β-10 are expressed in bovine ovarian follicles and upregulated in cumulus cells during meiotic maturation.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    General protein information

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    Preferred Names
    thymosin beta-4
    Names
    seraspenide
    t beta-4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001113231.2 → NP_001106702.2  thymosin beta-4

      Status: PROVISIONAL

      Source sequence(s)
      DAAA02001196
      Conserved Domains (1) summary
      pfam01290
      Location:3 → 41
      Thymosin; Thymosin beta-4 family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P62326.2 GenPept UniProtKB/Swiss-Prot:P62326

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.