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    dNK P-loop containing nucleoside triphosphate hydrolases superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843535, updated on 7-Sep-2023

    Summary

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    Gene symbol
    dNK
    Gene description
    P-loop containing nucleoside triphosphate hydrolases superfamily protein
    Primary source
    Araport:AT1G72040
    Locus tag
    AT1G72040
    See related
    TAIR:AT1G72040
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtdNK; deoxyribonucleoside kinase; F28P5.7; F28P5_7
    Summary
    Encodes a multisubstrate deoxyribonucleoside kinase that salvages DNA precursors.
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    Genomic context

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    See dNK in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (27111894..27114399, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene TCP family transcription factor Neighboring gene TonB-dependent heme receptor A Neighboring gene Acyl-CoA N-acyltransferases (NAT) superfamily protein Neighboring gene transcription factor IIIA Neighboring gene serine-type endopeptidase inhibitor Neighboring gene Chaperone DnaJ-domain superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Two thymidine kinases and one multisubstrate deoxyribonucleoside kinase salvage DNA precursors in Arabidopsis thaliana. Clausen AR, et al. FEBS J, 2012 Oct. PMID 22897443
    2. Analysis of the Arabidopsis nuclear proteome and its response to cold stress. Bae MS, et al. Plant J, 2003 Dec. PMID 14617066
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_105862.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables deoxynucleoside kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within deoxyribonucleoside monophosphate biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within nucleotide biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    P-loop containing nucleoside triphosphate hydrolases superfamily protein
    NP_565032.2
    • P-loop containing nucleoside triphosphate hydrolases superfamily protein; FUNCTIONS IN: phosphotransferase activity, alcohol group as acceptor, ATP binding; INVOLVED IN: nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Deoxynucleoside kinase (InterPro:IPR002624); Has 2859 Blast hits to 2855 proteins in 704 species: Archae - 0; Bacteria - 1629; Metazoa - 493; Fungi - 0; Plants - 69; Viruses - 71; Other Eukaryotes - 597 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      27111894..27114399 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105862.5 → NP_565032.2  P-loop containing nucleoside triphosphate hydrolases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565032.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9WRL5, A0A654ENJ6, Q501D4
      Conserved Domains (2) summary
      cd01673
      Location:268 → 456
      dNK; Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1. ...
      cl11966
      Location:179 → 249
      NT_Pol-beta-like; Nucleotidyltransferase (NT) domain of DNA polymerase beta and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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