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    AT1G29630 5'-3' exonuclease family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839840, updated on 15-Feb-2024

    Summary

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    Gene symbol
    AT1G29630
    Gene description
    5'-3' exonuclease family protein
    Primary source
    Araport:AT1G29630
    Locus tag
    AT1G29630
    See related
    TAIR:AT1G29630
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F15D2.37; F15D2_37
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    Genomic context

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    See AT1G29630 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    13
    Sequence:
    Chromosome: 1; NC_003070.9 (10349427..10353833)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Zinc finger C-x8-C-x5-C-x3-H type family protein Neighboring gene Cytochrome C oxidase polypeptide VIB family protein Neighboring gene senescence regulator (Protein of unknown function, DUF584) Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of Arabidopsis SUMO-interacting proteins that regulate chromatin activity and developmental transitions. Elrouby N, et al. Proc Natl Acad Sci U S A, 2013 Dec 3. PMID 24255109, Free PMC Article
    2. Multi-omics network-based functional annotation of unknown Arabidopsis genes. Depuydt T, et al. Plant J, 2021 Nov. PMID 34562334
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001084155.2
    NM_001123909.1
    NM_102703.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 5'-3' DNA exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables SUMO binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    5'-3' exonuclease family protein
    NP_001077624.1
    • 5'-3' exonuclease family protein; FUNCTIONS IN: DNA binding, catalytic activity, nuclease activity; INVOLVED IN: DNA repair; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 4 anthesis, F mature embryo stage, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: XPG conserved site (InterPro:IPR019974), XPG N-terminal (InterPro:IPR006085), DNA repair protein (XPGC)/yeast Rad (InterPro:IPR006084), 5'-3' exonuclease, C-terminal subdomain (InterPro:IPR020045), Helix-hairpin-helix motif, class 2 (InterPro:IPR008918), XPG/RAD2 endonuclease (InterPro:IPR006086); BEST Arabidopsis thaliana protein match is: 5'-3' exonuclease family protein (TAIR:AT1G18090.2); Has 2407 Blast hits to 2171 proteins in 377 species: Archae - 277; Bacteria - 0; Metazoa - 635; Fungi - 677; Plants - 227; Viruses - 36; Other Eukaryotes - 555 (source: NCBI BLink).
    NP_001117381.1
    • 5'-3' exonuclease family protein; FUNCTIONS IN: DNA binding, catalytic activity, nuclease activity; INVOLVED IN: DNA repair; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 4 anthesis, F mature embryo stage, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: DNA repair protein (XPGC)/yeast Rad (InterPro:IPR006084), 5'-3' exonuclease, C-terminal subdomain (InterPro:IPR020045), Helix-hairpin-helix motif, class 2 (InterPro:IPR008918), XPG/RAD2 endonuclease (InterPro:IPR006086); BEST Arabidopsis thaliana protein match is: 5'-3' exonuclease family protein (TAIR:AT1G18090.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_174256.2
    • 5'-3' exonuclease family protein; FUNCTIONS IN: nuclease activity; INVOLVED IN: DNA repair; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 4 anthesis, F mature embryo stage, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: XPG conserved site (InterPro:IPR019974), XPG N-terminal (InterPro:IPR006085), DNA repair protein (XPGC)/yeast Rad (InterPro:IPR006084), XPG/RAD2 endonuclease (InterPro:IPR006086); BEST Arabidopsis thaliana protein match is: 5'-3' exonuclease family protein (TAIR:AT1G18090.2); Has 2289 Blast hits to 1947 proteins in 363 species: Archae - 277; Bacteria - 0; Metazoa - 618; Fungi - 685; Plants - 238; Viruses - 12; Other Eukaryotes - 459 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      10349427..10353833
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001123909.1 → NP_001117381.1  5'-3' exonuclease family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001117381.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W434, B3H7B3
      Conserved Domains (2) summary
      cd09908
      Location:60 → 131
      H3TH_EXO1; H3TH domain of Exonuclease-1, a structure-specific, divalent-metal-ion dependent, 5' nuclease
      cl14812
      Location:1 → 52
      PIN_SF; PIN (PilT N terminus) domain: Superfamily

    2. NM_001084155.2 → NP_001077624.1  5'-3' exonuclease family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077624.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8L6Z7, Q9C7N8
      UniProtKB/TrEMBL
      A0A654EDW4
      Conserved Domains (3) summary
      cd09908
      Location:214 → 285
      H3TH_EXO1; H3TH domain of Exonuclease-1, a structure-specific, divalent-metal-ion dependent, 5' nuclease
      cd09857
      Location:1 → 206
      PIN_EXO1; PIN domain of Exonuclease-1, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs
      TIGR03674
      Location:1 → 296
      fen_arch; flap structure-specific endonuclease

    3. NM_102703.5 → NP_174256.2  5'-3' exonuclease family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_174256.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654EDW4
      Conserved Domains (2) summary
      cd09857
      Location:1 → 183
      PIN_EXO1; PIN domain of Exonuclease-1, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs
      cl22433
      Location:181 → 215
      H3TH_StructSpec-5'-nucleases; H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8L6Z7.2

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