PAPP2C phytochrome-associated protein phosphatase type 2C [Arabidopsis thaliana (thale cress)] - Gene

Summary

Go to the top of the page Help

Gene symbol: PAPP2C
Gene description: phytochrome-associated protein phosphatase type 2C
Primary source: Araport:AT1G22280
Locus tag: AT1G22280
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: phytochrome-associated protein phosphatase type 2C; T16E15.10; T16E15_10
Summary: Encodes a phytochrome-associated protein, PAPP2C (phytochrome-associated protein phosphatase type 2C). PAPP2C interacts in the nucleus with phyA (phytochrome A) and phyB. Functions as a regulator of phytochrome-interacting factor PIF3 by dephosphorylating phytochromes in the nucleus.
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See PAPP2C in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 6

Sequence:: Chromosome: 1; NC_003070.9 (7873867..7876018)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

PAPP2C interacts with RPW8.2 and negatively regulates salicylic acid-dependent defense responses.
Title: PAPP2C interacts with the atypical disease resistance protein RPW8.2 and negatively regulates salicylic acid-dependent defense responses in Arabidopsis.
Study show that PAPP2C interacts in the nucleus with phyA and phyB, and functions as a regulator of PIF3 by dephosphorylating phytochromes in the nucleus. [PAPP2C]
Title: A novel protein phosphatase indirectly regulates phytochrome-interacting factor 3 via phytochrome.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Homology

Orthologs from OrthoDB

NM_102079.5

Supported by ESTs:

NM_202154.2

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables myosin phosphatase activity	IEA Inferred from Electronic Annotation more info
enables phosphoprotein phosphatase activity	IDA Inferred from Direct Assay more info	PubMed
enables protein serine/threonine phosphatase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within protein dephosphorylation	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within red light signaling pathway	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in mitochondrion	ISM Inferred from Sequence Model more info
located_in nucleus	HDA more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	HDA more info	PubMed
located_in plasmodesma	HDA more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: phytochrome-associated protein phosphatase type 2C

NP_001185062.1

phytochrome-associated protein phosphatase type 2C (PAPP2C); CONTAINS InterPro DOMAIN/s: Protein phosphatase 2C-related (InterPro:IPR001932), Protein phosphatase 2C (InterPro:IPR015655), Protein phosphatase 2C, N-terminal (InterPro:IPR014045); BEST Arabidopsis thaliana protein match is: Protein phosphatase 2C family protein (TAIR:AT1G34750.1).

NP_564165.1

phytochrome-associated protein phosphatase type 2C (PAPP2C); FUNCTIONS IN: protein serine/threonine phosphatase activity, phosphoprotein phosphatase activity; INVOLVED IN: protein amino acid dephosphorylation, red light signaling pathway; LOCATED IN: nucleus, plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Protein phosphatase 2C-related (InterPro:IPR001932), Protein phosphatase 2C (InterPro:IPR015655), Protein phosphatase 2C, N-terminal (InterPro:IPR014045); BEST Arabidopsis thaliana protein match is: Protein phosphatase 2C family protein (TAIR:AT1G34750.1); Has 8206 Blast hits to 8190 proteins in 1131 species: Archae - 16; Bacteria - 1989; Metazoa - 1496; Fungi - 741; Plants - 2625; Viruses - 11; Other Eukaryotes - 1328 (source: NCBI BLink).

NP_973883.1

phytochrome-associated protein phosphatase type 2C; FUNCTIONS IN: protein serine/threonine phosphatase activity, phosphoprotein phosphatase activity; INVOLVED IN: protein amino acid dephosphorylation, red light signaling pathway; LOCATED IN: nucleus, plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Protein phosphatase 2C-related (InterPro:IPR001932), Protein phosphatase 2C (InterPro:IPR015655), Protein phosphatase 2C, N-terminal (InterPro:IPR014045); BEST Arabidopsis thaliana protein match is: Protein phosphatase 2C family protein (TAIR:AT1G34750.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

7873867..7876018

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001198133.1 → NP_001185062.1 phytochrome-associated protein phosphatase type 2C [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001185062.1

Status: REVIEWED

UniProtKB/TrEMBL

F4I1B4

Conserved Domains (1) summary

cd00143
Location:32 → 286

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
NM_102079.5 → NP_564165.1 phytochrome-associated protein phosphatase type 2C [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_564165.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q3ED74, Q8LFF8, Q9LME4

UniProtKB/TrEMBL

A0A178WBX4, A0A5S9VIA9

Conserved Domains (1) summary

cd00143
Location:32 → 280

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
NM_202154.2 → NP_973883.1 phytochrome-associated protein phosphatase type 2C [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_973883.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9LME4

Conserved Domains (1) summary

cd00143
Location:32 → 191

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...