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    lms lateral muscles scarcer [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37322, updated on 18-Sep-2024

    Summary

    Official Symbol
    lmsprovided by FlyBase
    Official Full Name
    lateral muscles scarcerprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034520
    Locus tag
    Dmel_CG13424
    See related
    AllianceGenome:FB:FBgn0034520
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13424; Dmel\CG13424; Lms
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in flight and larval somatic muscle development. Predicted to be active in nucleus. Is expressed in embryonic thoracic segment; embryonic/larval muscle system; and extended germ band embryo. Human ortholog(s) of this gene implicated in syndromic microphthalmia 11. Orthologous to human VAX1 (ventral anterior homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    NEW
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    Genomic context

    Location:
    57A5-57A5; 2-91 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20556877..20559953)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16444382..16447458)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Cuticular protein 57A Neighboring gene Odorant-binding protein 57d Neighboring gene uncharacterized protein Neighboring gene BLOC-1 related complex subunit 7 Neighboring gene antisense RNA:CR44653 Neighboring gene Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase Neighboring gene uncharacterized protein Neighboring gene quasimodo

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in central nervous system development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in flight IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in larval somatic muscle development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in neuron differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    lateral muscles scarcer
    Names
    CG13424-PB
    CG13424-PC
    lms-PB
    lms-PC

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      20556877..20559953
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137647.2NP_611491.2  lateral muscles scarcer, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611491.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBV6, Q058W3, Q8MZ02
      Conserved Domains (2) summary
      pfam00046
      Location:89142
      Homeobox; Homeobox domain
      cl19886
      Location:33106
      Cnd2; Condensin complex subunit 2
    2. NM_001299706.1NP_001286635.1  lateral muscles scarcer, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286635.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBV6, Q058W3, Q8MZ02
      Conserved Domains (2) summary
      pfam00046
      Location:89142
      Homeobox; Homeobox domain
      cl19886
      Location:33106
      Cnd2; Condensin complex subunit 2