OLEO1 oleosin 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Gene symbol: OLEO1
Gene description: oleosin 1
Primary source: Araport:AT4G25140
Locus tag: AT4G25140
See related: TAIR:AT4G25140
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F24A6.9; OLE1; oleosin 1; OLEOSIN 1
Summary: Encodes oleosin1, a protein found in oil bodies, involved in seed lipid accumulation. Suppression of OLEO1 (and OLEO2) resulted in an aberrant phenotype of embryo cells that contain unusually large oilbodies that are not normally observed in seeds. Changes in the size of oilbodies caused disruption of storage organelles, altering accumulation of lipids and proteins and causing delay in germination. Functions in freezing tolerance of seeds.
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Genomic context

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See OLEO1 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 2

Sequence:: Chromosome: 4; NC_003075.7 (12900430..12901577)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

This present study identifies the distinct physiological substrates of Arabidopsis serine/threonine/tyrosine protein kinase (STYK) and its role in seed oil accumulation; the role of Arabidopsis OLE1, a major seed oil body protein has also been elucidated.
Title: Arabidopsis serine/threonine/tyrosine protein kinase phosphorylates oil body proteins that regulate oil content in the seeds.
Data show that the sequential proteolysis of the five oleosins OLE1-OLE5 begins just prior to lipid degradation.
Title: Ubiquitin-Mediated Proteasomal Degradation of Oleosins is Involved in Oil Body Mobilization During Post-Germinative Seedling Growth in Arabidopsis.
Analyses of oil bodies were carried out with different genotypes: the wild type and three mutants affected in the accumulation of various oleosins (OLE1, OLE2, and OLE4), three major OB proteins.[OLE4]
Title: Specialization of oleosins in oil body dynamics during seed development in Arabidopsis seeds.
oleosin and perilipin were expressed in yeast cells and their targeting to LDs, membrane association and function in neutral lipid homeostasis
Title: Expression of oleosin and perilipins in yeast promotes formation of lipid droplets from the endoplasmic reticulum.
The central promoter region of OLEOSIN, responsible for seed specificity and LEC2 activation, was determined by 5'-deletion analysis.
Title: Efficient LEC2 activation of OLEOSIN expression requires two neighboring RY elements on its promoter.
The accumulation of OLEO1 is instrumental in controlling oilbody structure and lipid accumulation in developing seeds.
Title: The accumulation of oleosins determines the size of seed oilbodies in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_118646.2

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within lipid storage	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to freezing	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within seed germination	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within seed oilbody biogenesis	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within seed oilbody biogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	ISM Inferred from Sequence Model more info
located_in monolayer-surrounded lipid storage body	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: oleosin 1

NP_194244.1

oleosin 1 (OLEO1); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: response to freezing, lipid storage, seed germination, seed oilbody biogenesis; LOCATED IN: monolayer-surrounded lipid storage body, integral to membrane, membrane; EXPRESSED IN: shoot apex; CONTAINS InterPro DOMAIN/s: Oleosin (InterPro:IPR000136); BEST Arabidopsis thaliana protein match is: oleosin3 (TAIR:AT5G51210.1); Has 551 Blast hits to 551 proteins in 51 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 551; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).