U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    gfra1b gdnf family receptor alpha 1b [ Danio rerio (zebrafish) ]

    Gene ID: 79377, updated on 27-Mar-2024

    Summary

    Official Symbol
    gfra1bprovided by ZNC
    Official Full Name
    gdnf family receptor alpha 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-010226-3
    See related
    Ensembl:ENSDARG00000102564 AllianceGenome:ZFIN:ZDB-GENE-010226-3
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    gfralpha1b
    Summary
    Predicted to enable signaling receptor activity. Acts upstream of or within enteric nervous system development. Predicted to be located in plasma membrane. Predicted to be anchored component of membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in nervous system; presumptive enteric nervous system; pronephric duct; and vagal neural crest. Orthologous to human GFRA1 (GDNF family receptor alpha 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See gfra1b in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (29763656..29818209)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (29648754..29703307)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene SH2 domain containing 4Bb Neighboring gene neuregulin 3b Neighboring gene uncharacterized LOC108191725 Neighboring gene attractin-like 1b Neighboring gene TruB pseudouridine (psi) synthase family member 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables signaling receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within enteric nervous system development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in nervous system development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of receptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in side of membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    GDNF family receptor alpha-1b

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131731.1NP_571806.1  GDNF family receptor alpha-1b precursor

      See identical proteins and their annotated locations for NP_571806.1

      Status: PROVISIONAL

      Source sequence(s)
      AY436321
      UniProtKB/TrEMBL
      Q98TT8
      Related
      ENSDARP00000137090.1, ENSDART00000161533.2
      Conserved Domains (2) summary
      smart00907
      Location:41123
      GDNF; GDNF/GAS1 domain
      pfam02351
      Location:255349
      GDNF; GDNF/GAS1 domain

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      29763656..29818209
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394850.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      181771..182684
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)