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    PLCD1 phospholipase C delta 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696860, updated on 5-Mar-2024

    Summary

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    Official Symbol
    PLCD1provided by VGNC
    Official Full Name
    phospholipase C delta 1provided by VGNC
    Primary source
    VGNC:VGNC:76166
    Locus tag
    EGK_11798
    See related
    Ensembl:ENSMMUG00000000985
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (93445286..93467664, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (104717226..104739568)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene CTD small phosphatase like Neighboring gene microRNA mir-26a-1 Neighboring gene villin like Neighboring gene serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform pseudogene Neighboring gene DLEC1 cilia and flagella associated protein Neighboring gene acetyl-CoA acyltransferase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol phospholipase C activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
    Names
    1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
    XP_001089399.1
    XP_014986841.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      93445286..93467664 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015131355.1 → XP_014986841.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X2

      UniProtKB/TrEMBL
      F6VRS9, I0FHZ5
      Related
      ENSMMUP00000080931.1, ENSMMUT00000085235.1
      Conserved Domains (7) summary
      cd00275
      Location:629 → 755
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08593
      Location:295 → 596
      PI-PLCc_delta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta
      PLN02228
      Location:212 → 755
      PLN02228; Phosphoinositide phospholipase C
      cd13363
      Location:22 → 139
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      pfam00169
      Location:30 → 130
      PH; PH domain
      pfam09279
      Location:213 → 295
      EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
      pfam14788
      Location:159 → 208
      EF-hand_10; EF hand

    2. XM_001089399.4 → XP_001089399.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1

      See identical proteins and their annotated locations for XP_001089399.1

      UniProtKB/TrEMBL
      A0A5F7ZCB2, A0A8J8XPQ2, F6VRS9, G7MJ18
      Related
      ENSMMUP00000063247.1, ENSMMUT00000093771.1
      Conserved Domains (7) summary
      cd00275
      Location:650 → 776
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08593
      Location:316 → 617
      PI-PLCc_delta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta
      PLN02228
      Location:233 → 776
      PLN02228; Phosphoinositide phospholipase C
      cd13363
      Location:43 → 160
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      pfam00169
      Location:51 → 151
      PH; PH domain
      pfam09279
      Location:234 → 316
      EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
      pfam14788
      Location:180 → 229
      EF-hand_10; EF hand

    RNA

    1. XR_001443060.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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